Quantum dots (QDs) are used for imaging and transport of therapeutics. Here we demonstrate rapid absorption across the small intestine and targeted delivery of QDs with bound materials to the liver sinusoidal endothelial cells (LSECs) or hepatocytes in vitro and in vivo following oral administration. QDs were radiolabeled with ³ H-oleic acid, with a fluorescent tag or <sup>14</su ...

Free traveling Rossby wave normal modes (RNMs) are often investigated through large-scale space-time spectral analyses, which therefore is subject to observational availability, especially in the mesosphere. Ground-based mesospheric observations were broadly used to identify RNMs mostly according to the periods of RNMs without resolving their horizontal scales. The current study diagnoses zonal ...

Hjerte- og karsykdommer er en av hovedårsakene til for tidlig død. Fokus på forebyggende tiltak er derfor viktig. Fysisk aktivitet er et gunstig forebyggende tiltak, men det er mangelfull kunnskap om sammenhengen mellom fysisk aktivitet, risikofaktorer for hjerte-og karsykdom og død hos urfolk, som eksempelvis samer. Historisk har den fleretniske befolkningen i nord hatt høyere hjerte- og kardødelighet ...

Introduction: The relationship between circulating prolactin and invasive breast cancer has been investigated previously, but the association between prolactin levels and in situ breast cancer risk has received less attention.<p> <p>Methods: We analysed the relationship between pre-diagnostic prolactin levels and the risk of in situ breast cancer overall, and by menopausal status and use of ...

LTX-315 has been developed as an amphipathic cationic peptide that kills cancer cells. Here, we investigated the putative involvement of mitochondria in the cytotoxic action of LTX-315. Subcellular fractionation of LTX-315-treated cells, followed by mass spectrometric quantification, revealed that the agent was enriched in mitochondria. LTX-315 caused an immediate arrest of mitochondrial ...

Kan man ane en viss risiko idet kunstutdanningsinstitusjonene nå overtar ansvaret individuelt for det arbeidet det nasjonale og tverrkunstneriske stipendiatprogrammet for kunstnerisk utviklingsarbeid (PKU), har utført? spør Edvine Larssen og Lisa Torell.

​While the criminal law and security governance aspects of the July 22 terror attack in Norway have been extensively analyzed in the academic literature, much less attention has been given to processes involving civil law, legal mobilization and legal-bureaucratic processes. ​The slow workings of the law mean that the aftermath of July 22 is still unfolding in different legal processes. This ...

There is a high regard for peracetic acid (PAA)-based disinfectants in recirculating aquaculture systems (RAS) because of the low risk of bioaccumulation, fast degradation with neutral residuals and minimal impact on biofilter performance. However, the no-observed-effect concentration in Atlantic salmon parr is unknown. The present study evaluated the effect of an acute PAA exposure on Atlantic ...

Objective: We explored the effects of playing the piano on patients with cognitive impairment after mild traumatic brain injury (mTBI) and, addressed the question if this approach would stimulate neural networks in re-routing neural connections and link up cortical circuits that had been functional inhibited due to disruption of brain tissue. Functional neuroimaging scans (fMRI) and neuropsychological ...

The current study focuses on how different scales with varying demands can affect our subjective assessments. We carried out 2 experiments in which we asked participants to rate how happy or sad morphed images of faces looked. The two extremes were the original happy and original sad faces with 4 morphs in between. We manipulated language of the task—namely, half of the participants carried it ...