dc.contributor.author | Hegstad, Kristin | |
dc.contributor.author | Longva, Jørn-Åge | |
dc.contributor.author | Hide, Reidar | |
dc.contributor.author | Aasnæs, Bettina | |
dc.contributor.author | Lunde, Tracy Tamara Munthali | |
dc.contributor.author | Simonsen, Gunnar Skov | |
dc.date.accessioned | 2015-03-02T09:58:08Z | |
dc.date.available | 2015-10-31T06:50:05Z | |
dc.date.issued | 2014-08-19 | |
dc.description.abstract | A linezolid-resistant, vancomycin-susceptible Enterococcus faecium strain was isolated from 3 patients who had not received linezolid. The first patient was hospitalized in the same hospitals and wards as the 2 following patients. The E. faecium isolates were resistant to linezolid (minimum inhibitory concentration 8–32 mg/l), ampicillin, and high levels of gentamicin. Resistance to linezolid was associated with a G2576T mutation in 23S rDNA. The cfr linezolid resistance gene was not detected. The 3 isolates showed identical DNA fingerprints by pulsed-field gel electrophoresis, belonged to ST117, and harboured virulence genes esp, hyl, acm, efaAfm, srgA, ecbA, scm, pilA, pilB, and pstD typically associated with high-risk E. faecium genotypes. The linezolid-resistant E. faecium high-risk clone caused bacteraemia in the first 2 cancer patients and survived in the hospital environment for more than a year before appearing in the urethral catheter of the third patient. | en |
dc.identifier.citation | Scandinavian Journal of Infectious Diseases 46(2014) nr. 10 s. 712-715 | en_US |
dc.identifier.cristinID | FRIDAID 1175563 | |
dc.identifier.doi | 10.3109/00365548.2014.923107 | |
dc.identifier.issn | 0036-5548 | |
dc.identifier.uri | https://hdl.handle.net/10037/7268 | |
dc.identifier.urn | URN:NBN:no-uit_munin_6859 | |
dc.language.iso | eng | en_US |
dc.publisher | Informa Healthcare | en_US |
dc.rights.accessRights | openAccess | |
dc.subject | VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Infeksjonsmedisin: 776 | en_US |
dc.subject | VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Communicable diseases: 776 | en_US |
dc.subject | linezolid resistance | en |
dc.subject | Enterococcus faecium | en |
dc.subject | cluster | en |
dc.subject | ST117 | en |
dc.subject | Scandinavia | en |
dc.title | Cluster of linezolid-resistant Enterococcus faecium ST117 in Norwegian hospitals | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |