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dc.contributor.authorShin, Aesun
dc.contributor.authorSandin, Sven
dc.contributor.authorLöf, Marie
dc.contributor.authorMargolis, Karen L.
dc.contributor.authorKim, Kyeezu
dc.contributor.authorCouto, Elisabeth
dc.contributor.authorAdami, Hans Olov
dc.contributor.authorWeiderpass, Elisabete
dc.date.accessioned2016-03-08T12:34:07Z
dc.date.available2016-03-08T12:34:07Z
dc.date.issued2015-11-09
dc.description.abstractBackground: We aimed to estimate the effect of alcohol consumption on breast cancer risk and to test whether overweight and obesity modifies this association. <p>Methods: We included in the analysis 45,233 women enrolled in the Swedish Women’s Lifestyle and Health study between 1991 and 1992. Participants were followed for occurrence of breast cancer and death until December 2009. Poisson regression models were used, and analyses were done for overall breast cancer and for estrogen receptor positive or negative (ER+, ER-) and progesterone receptor positive and negative (PR+, PR-) tumors separately. <p>Results: A total of 1,385 breast cancer cases were ascertained during the follow-up period. Overall, we found no statistically significant association between alcohol intake and breast cancer risk after adjustment for confounding, with an estimated relative risk (RR) of 1.01 (95 % CI: 0.98–1.04) for an increment in alcohol consumption of 5 g/day. A statistically significant elevated breast cancer risk associated with higher alcohol consumption was found only among women with BMI ≤25 (RR 1.03, 95 % CI 1.0–1.05 per 5 g/day increase). <p>Conclusion: An increase in breast cancer risk with higher alcohol consumption was found for breast cancers in women with a BMI ≤25 kg/m2.en_US
dc.descriptionPublished ersion, also available at <a href=http://dx.doi.org/10.1186/s12885-015-1896-3> http://dx.doi.org/10.1186/s12885-015-1896-3 </a>en_US
dc.identifier.citationBMC Cancer (2015) 15:881en_US
dc.identifier.cristinIDFRIDAID 1317246
dc.identifier.doi10.1186/s12885-015-1896-3
dc.identifier.issn1471-2407
dc.identifier.urihttps://hdl.handle.net/10037/8756
dc.identifier.urnURN:NBN:no-uit_munin_8334
dc.language.isoengen_US
dc.publisherBioMed Centralen_US
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Forebyggende medisin: 804en_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Preventive medicine: 804en_US
dc.subjectBreast canceren_US
dc.subjectAlcoholen_US
dc.subjectBody mass indexen_US
dc.subjectHormone receptoren_US
dc.titleAlcohol consumption, body mass index and breast cancer risk by hormone receptor status: Women' Lifestyle and Health Studyen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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