Vis enkel innførsel

The Spot 42 RNA: A regulatory small RNA with roles in the central metabolism

dc.contributor.authorHaugen, Peik
dc.contributor.authorBækkedal, Cecilie
dc.date.accessioned2016-03-15T09:41:43Z
dc.date.available2016-03-15T09:41:43Z
dc.date.issued2015-09-01
dc.description.abstractThe Spot 42 RNA is a 109 nucleotide long (in Escherichia coli) noncoding small regulatory RNA (sRNA) encoded by the spf (spot fourty-two) gene. spf is found in gamma-proteobacteria and the majority of experimental work on Spot 42 RNA has been performed using E. coli, and recently Aliivibrio salmonicida. In the cell Spot 42 RNA plays essential roles as a regulator in carbohydrate metabolism and uptake, and its expression is activated by glucose, and inhibited by the cAMP-CRP complex. Here we summarize the current knowledge on Spot 42, and present the natural distribution of spf, show family-specific secondary structural features of Spot 42, and link highly conserved structural regions to mRNA target binding.en_US
dc.descriptionAccepted manuscript version. Published version at <a href=http://doi.org/10.1080/15476286.2015.1086867>http://doi.org/10.1080/15476286.2015.1086867</a>.en_US
dc.identifier.citationRNA Biology 2015, 12(10):1071-1077en_US
dc.identifier.cristinIDFRIDAID 1318911
dc.identifier.doi10.1080/15476286.2015.1086867
dc.identifier.issn1555-8584
dc.identifier.urihttps://hdl.handle.net/10037/8949
dc.identifier.urnURN:NBN:no-uit_munin_8525
dc.language.isoengen_US
dc.publisherTaylor & Francisen_US
dc.rights.accessRightsopenAccess
dc.subjectgamma proteobacteriaen_US
dc.subjectnon-coding RNAen_US
dc.subjectpirinen_US
dc.subjectsRNAen_US
dc.subjectsmall RNAen_US
dc.subjectSpot 42en_US
dc.subjectspfen_US
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470en_US
dc.titleThe Spot 42 RNA: A regulatory small RNA with roles in the central metabolismen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


Tilhørende fil(er)

Thumbnail
Navn:
article.pdf
Størrelse:
604.0Kb
Format:
PDF
Beskrivelse:
accepted manuscript version
Åpne

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel