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norskBlar i forfatter "Braaten, Tonje"
Viser treff 21-40 av 72
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Differential expression of the miR-17-92 cluster and miR-17 family in breast cancer according to tumor type; results from the Norwegian Women and Cancer (NOWAC) study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-03)<i>Background</i> - MicroRNAs (miRNAs) are promising biomarkers due to their structural stability and distinct expression profile in various cancers. We wanted to explore the miRNA expression in benign breast tissue and breast cancer subgroups in the Norwegian Women and Cancer study.<p> <p><i>Methods</i> - Specimens and histopathological data from study participants in Northern Norway diagnosed ... -
Distribution of risk factors for cardiovascular disease and the estimated 10-year risk of acute myocardial infarction or cerebral stroke in Sami and non-Sami populations: The SAMINOR 2 Clinical Survey.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-27)<p><i>Objective</i>: This study aimed to assess and compare the distribution of cardiovascular risk factors and the estimated 10-year risk of fatal or non-fatal acute myocardial infarction (AMI) or cerebral stroke (CS) among the Sami and non-Sami populations of Northern Norway.</p> <p><i>Methods</i>: The SAMINOR 2 Clinical Survey is a cross-sectional survey conducted in 10 municipalities in the ... -
Epithelial ovarian cancer subtypes attributable to smoking in the Norwegian Women and Cancer Study, 2012
(Journal article; Peer reviewed; Tidsskriftartikkel, 2016-01-14)Among European women, ovarian cancer is the fifth most common cancer. Smoking is an established risk factor for mucinous tumors. We estimated the impact of smoking in Norwegian women using population attributable fractions (PAFs) of epithelial ovarian cancer (EOC), by invasiveness and by histological subtypes in the Norwegian Women and Cancer Study with an average of 13.2 years of follow-up. ... -
Exploring geographical differences in the incidence of colorectal cancer in the Norwegian women and cancer study: A population-based prospective study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-08)<i>Purpose</i>: Norway has experienced an unexplained, steep increase in colorectal cancer (CRC) incidence in the last half-century, with large differences across its counties. We aimed to determine whether geographical distribution of lifestyle-related CRC risk factors can explain these geographical differences in CRC incidence in Norwegian women.<p><p> <i>Methods</i>: We followed a nationally ... -
Expression and function of the miR-143/145 cluster in vitro and in vivo in human breast cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-26)MicroRNAs (miRNAs) are small non-coding RNAs that function as post-transcriptional regulators of gene expression and are dysregulated in cancer. Studies of miRNAs to explore their potential as diagnostic and prognostic markers are of great scientific interest. Here, we investigate the functional properties and expression of the miR-143/145 cluster in breast cancer (BC) in vitro and in vivo. The ER ... -
Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
The fraction of breast cancer attributable to smoking: The Norwegian women and cancer study 1991–2012
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-09)Background: Results from several recent cohort studies on smoking and breast cancer incidence and mortality suggest that the burden of smoking on society is underestimated. We estimated the fraction of breast cancer attributable to smoking in the Norwegian Women and Cancer Study, a nationally representative prospective cohort study. <br> Methods: We followed 130 053 women, aged 34–70 years, who ... -
The fraction of lung cancer attributable to smoking in the Norwegian Women and Cancer (NOWAC) Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-27)<i>Background</i> - We examined the association between active and passive smoking and lung cancer risk and the population attributable fraction (PAF) of lung cancer due to active smoking, in the Norwegian Women and Cancer Study, a nationally representative prospective cohort study.<br><br> <i>Methods</i> - We followed 142,508 women, aged 31–70 years, who completed a baseline questionnaire between ... -
The hazards of death by smoking in middle-aged women
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Recent studies have found that the risk of death continues to increase among female smokers, as compared with women who have never smoked. We wanted to examine the effect of smoking on all-cause and causespecific mortality and calculate the corresponding population attributable fraction (PAF) of mortality in the Norwegian women and cancer study; a nationally representative prospective cohort ... -
High coffee consumption and different brewing methods in relation to postmenopausal endometrial cancer risk in the Norwegian women and cancer study: A population-based prospective study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)<i>Background</i>: Coffee and its compounds have been proposed to inhibit endometrial carcinogenesis. Studies in the Norwegian population can be especially interesting due to the high coffee consumption and increasing incidence of endometrial cancer in the country.<p> <p><i>Methods</i>: A total of 97 926 postmenopausal Norwegian women from the population-based prospective Norwegian Women and ... -
Impact of referral templates on patient experience of the referral and care process: A cluster randomised trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-24)Objectives: To evaluate if a referral intervention improves the patient experience of the referral and treatment process. <p>Setting: Interface between 14 primary care surgeries and a district general hospital. <p>Participants: The 14 general practitioner (GP) surgeries (7 intervention, 7 control) in the area around the University Hospital of North Norway Harstad were randomised and all completed ... -
Levonorgestrel-releasing intrauterine system use is associated with a decreased risk of ovarian and endometrial cancer, without increased risk of breast cancer. Results from the NOWAC Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-02)<p><i>Objective</i>: Women with ovarian cancer have poor survival rates, which have proven difficult to improve; therefore primary prevention is important. The levonorgestrel-releasing intrauterine system (LNG-IUS) prevents endometrial cancer, and recent studies suggested that it may also prevent ovarian cancer, but with a concurrent increased risk of breast cancer. We compared adjusted risks of ... -
Lifetime number of years of menstruation as a risk index for postmenopausal endometrial cancer in the Norwegian Women and Cancer Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-21)<p><i>Introduction</i>: Lifetime number of years of menstruation (LNYM) reflects a woman's cumulative exposure to endogenous estrogen and can be used as a measure of the combined effect of reproductive factors related to endometrial cancer (EC) risk.</p> <p><i>Material and methods</i>: We aimed to study the association between LNYM and EC risk among postmenopausal women and calculate the population ... -
Lower attendance rates in BreastScreen Norway among immigrants across all levels of socio-demographic factors: a population-based study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-03)<i>Background:</i> Several studies have shown that immigrants attend mammographic screening less frequently than non-immigrants. Studies have also shown that attendance is influenced by socio-demographic factors. We aimed to describe the relationship between socio-demographic factors and first attendance among immigrant and non-immigrant women invited to BreastScreen Norway.<p> <p><i>Methods:</i> ... -
Lung function and prevalence of respiratory symptoms in Norwegian crab processing workers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-20)Background: Seafood processing workers have an increased risk of developing occupational asthma. This has not been studied among Norwegian crab processing workers, nor has the respiratory health of exposed workers been compared to a control group. <br>Objectives: Assessing the impact of working in the crab processing industry on workers ’ respiratory health. <br>Design: A cross-sectional study ... -
Macronutrient composition of the diet and prospective weight change in participants of the EPIC-PANACEA study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Background: The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. Methods: 373,803 subjects aged 25–70 years were recruited in 10 European countries (1992–2000) in the PANACEA project of the EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and weight and height were measured at baseline and ... -
Mediating Role of Lifestyle Behaviors in the Association between Education and Cancer: Results from the European Prospective Investigation into Cancer and Nutrition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-09)Background: Many studies have shown that socioeconomic position (SEP) is associated with the incidence of malignant tumors at different sites. This study aims to estimate the association between educational level (as proxy for SEP) and cancer incidence and to understand whether the observed associations might be partially explained by lifestyle behaviors.<p> <p>Methods: The analyses were performed ... -
A method for sensitivity analysis to assess the effects of measurement error in multiple exposure variables using external validation data
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-13)Background:<br>Measurement error in self-reported dietary intakes is known to bias the association between dietary intake and a health outcome of interest such as risk of a disease. The association can be distorted further by mismeasured confounders, leading to invalid results and conclusions. It is, however, difficult to adjust for the bias in the association when there is no internal validation ... -
Milk and risk of colorectal, colon and rectal cancer in the Norwegian Women and Cancer (NOWAC) Cohort Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-17)According to World Cancer Research Fund International/American Institute for Cancer Research, it is ‘probable’ that dairy products decrease the risk of colorectal cancer (CRC). However, meta-analyses restricted to women have not shown associations between milk intake and risk of CRC. The aim of this study was to examine the association between milk intake and risk of CRC, colon cancer and rectal ...
