Browsing by Author "Dalhaug, Astrid"
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Palliative radiotherapy with or without additional care by a multidisciplinary palliative care team in patients with newly diagnosed cancer: A retrospective matched pairs comparison
Nieder, Carsten; Dalhaug, Astrid; Pawinski, Adam; Haukland, Ellinor; Mannsåker, Bård; Engljähringer, Kirsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-07)Purpose: To analyze survival after early palliative radiotherapy (RT) in patients managed exclusively by regular oncology staff or a multidisciplinary palliative care team (MPCT) in addition. <p>Methods: Retrospective matched pairs analysis. Comparison of two groups of 29 patients each: MPCT versus none. Early RT started within three months after cancer diagnosis. <p>Results: Bone and brain ... -
Palliative Radiotherapy with or without Additional Care by a Multidisciplinary Palliative Care Team: A Retrospective Comparison
Nieder, Carsten; Angelo, Kent; Dalhaug, Astrid; Pawinski, Adam; Aandahl, Gro; Haukland, Ellinor; Engljähringer, Kirsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Percent of remaining life on palliative radiation treatment: solely a function of fractionation?
Nieder, Carsten; Mannsåker, Bård; Dalhaug, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-14)Background: This study analyzed the percent of remaining life (PRL) on treatment in patients irradiated for bone metastases. Bone metastases were treated together with other target volumes, if indicated, e.g. a 10-fraction treatment course that included brain and bone metastases. PRL was determined by calculating the time between start and finish of palliative radiotherapy (minimum 1 day in case of ... -
Prognostic factors and independent validation of a risk stratification model in octogenarian patients irradiated for brain metastases
Nieder, Carsten; Dalhaug, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-25)Background/Aim: This study aimed at validation of a prognostic model, originally developed by Rades et al., in an age-restricted, particularly vulnerable subgroup of patients with brain metastases, because international variations in clinical practice and survival outcomes may impact on the performance of survival prediction tools. Patients and Methods: Retrospectively, data from a single institution ... -
Prognostic Impact of the Tumor Marker CA 15-3 in Patients With Breast Cancer and Bone Metastases Treated With Palliative Radiotherapy
Nieder, Carsten; Dalhaug, Astrid; Haukland, Ellinor; Mannsåker, Bård; Pawinski, Adam (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-25)<p><i>Background</i>: The aim of the study was to explore the prognostic impact of different abnormal blood tests and the tumor marker CA 15-3 as well as established parameters such as disease extent and receptor status in patients with bone metastases from breast cancer who received palliative radiotherapy in addition to contemporary systemic treatment.</p> <p><i>Methods</i>: This was a ... -
Recursive partitioning analysis of systemic therapy after radiotherapy in patients with brain metastases
Nieder, Carsten; Dalhaug, Astrid; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03)Purpose: The purpose of this study was to identify factors associated with the initiation or continuation of systemic treatment after brain irradiation. The outcome of interest was a utilization rate of at least 75%, given that active extracranial disease is common in patients with brain metastases. If left untreated, extracranial disease limits survival, regardless of successful local treatment of ... -
A review of clinical trials of cetuximab combined with radiotherapy for non-small cell lung cancer
Nieder, Carsten; Pawinski, Adam; Dalhaug, Astrid; Andratschke, Nicolaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)Treatment of non-small cell lung cancer (NSCLC) is challenging in many ways. One of the problems is disappointing local control rates in larger volume disease. Moreover, the likelihood of both nodal and distant spread increases with primary tumour (T-) stage. Many patients are elderly and have considerable comorbidity. Therefore, aggressive combined modality treatment might be contraindicated or ... -
Serum lactate dehydrogenase contributes to prognostic assessment in patients with oligometastatic cancer and brain involvement
Nieder, Carsten; Dalhaug, Astrid; Pawinski, Adam (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01)<p><i>Background/Aim - </i>The aim of this study was to analyze the prognostic impact of serum lactate dehydrogenase (LDH) in patients with oligometastatic brain metastases, arbitrarily defined as max. Four brain lesions and 5 metastatic lesions overall. <p><i>Patients and Methods - </i>This was a retrospective single institution analysis. Overall, 42 patients were identified from a prospectively ... -
Survival Prediction Score: A Simple but Age-Dependent Method Predicting Prognosis in Patients Undergoing Palliative Radiotherapy
Angelo, Kent; Dalhaug, Astrid; Pawinski, Adam; Haukland, Ellinor; Nieder, Carsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Towards Improved Prognostic Scores Predicting Survival in Patients with Brain Metastases: A Pilot Study of Serum Lactate Dehydrogenase Levels
Nieder, Carsten; Marienhagen, Kirsten; Dalhaug, Astrid; Norum, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)Accurate prognostic information is desirable when counselling patients with brain metastases regarding their therapeutic options and life expectancy. Based on previous studies, we selected serum lactate dehydrogenase (LDH) as a promising factor on which we perform a pilot study investigating methodological aspects of biomarker studies in patients with brain metastases, before embarking on large-scale ... -
An uncommon presentation and course of metastatic malignant melanoma : case report
Dalhaug, Astrid; Norum, Jan; Pawinski, Adam; Nieder, Carsten (Journal article; Tidsskriftartikkel, 2007)