• Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis 

      Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten Wang; Storheim, Kjersti; Brox, Jens Ivar; Solberg, Tore; Rekeland, Frode; Franssen, Eric; Weber, Clemens; Brisby, Helena; Grundnes, Oliver; Algaard, Knut; Bøker, Tordis; Banitalebi, Hasan; Indrekvam, Kari; Hellum, Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-05)
      BACKGROUND In patients with lumbar spinal stenosis and degenerative spondylolisthesis, it is uncertain whether decompression surgery alone is noninferior to decompression with instrumented fusion. METHODS We conducted an open-label, multicenter, noninferiority trial involving patients with symptomatic lumbar stenosis that had not responded to conservative management and who had single-level ...
    • Effect of caudal epidural steroid or saline injection in chronic lumbar radiculopathy: multicentre, blinded, randomised controlled trial 

      Iversen, Trond; Solberg, Tore; Romner, Bertil; Wilsgaard, Tom; Twisk, Jos WR; Anke, Audny; Nygaard, Øystein Petter; Hasvold, Toralf; Ingebrigtsen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Objective To assess the efficacy of caudal epidural steroid or saline injection in chronic lumbar radiculopathy in the short (6 weeks), intermediate (12 weeks), and long term (52 weeks).<p> <p>Design Multicentre, blinded, randomised controlled trial. <p>Setting Outpatient multidisciplinary back clinics of five Norwegian hospitals. <p>Participants Between October 2005 and February 2009, 461 ...
    • Effectiveness of surgery for sciatica with disc herniation is not substantially affected by differences in surgical incidences among three countries: results from the Danish, Swedish and Norwegian spine registries 

      Lagerbäck, Tobias; Fritzell, Peter; Hägg, Olle; Nordvall, Dennis; Lønne, Greger; Solberg, Tore; Andersen, Mikkel Ø.; Eiskjær, Søren; Gehrchen, Martin; Jacobs, Wilco C.; van Hooff, Miranda L.; Gerdhem, Paul (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-29)
      Purpose Yearly incidence of surgery for symptomatic lumbar disc herniation varies and is 29/100,000 in Sweden, 46/100,000 in Denmark and 58/100,000 in Norway. This variation was used to study whether diferences in surgical incidence were associated with diferences in preoperative patient characteristics as well as patient-reported outcomes.<p> Methods Data from the national spine registers in ...
    • Evaluation of the EQ-5D-3L and 5L versions in low back pain patients 

      Garratt, Andrew; Furunes, Håvard; Hellum, Christian; Solberg, Tore; Brox, Jens Ivar; Storheim, Kjersti; Johnsen, Lars Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-28)
      <p>Background: The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respectively. Evidence from healthy and sick populations shows that the additional two response categories improve measurement properties but there has not been a concurrent comparison ...
    • Impact of the number of previous lumbar operations on patient-reported outcomes after surgery for lumbar spinal stenosis or lumbar disc herniation 

      Riksaasen, Anniken S.; Kaur, Simran; Solberg, Tore; Austevoll, Ivar Magne; Brox, Jens Ivar; Dolatowski, Filip Celestyn; Hellum, Christian; Kolstad, Frode; Lønne, Greger; Nygaard, Øystein Petter; Ingebrigtsen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-15)
      Aims - Repeated lumbar spine surgery has been associated with inferior clinical outcomes. This study aimed to examine and quantify the impact of this association in a national clinical register cohort.<p> <p>Methods - This is a population-based study from the Norwegian Registry for Spine surgery (NORspine). We included 26,723 consecutive cases operated for lumbar spinal stenosis or lumbar disc ...
    • Is the presence of foraminal stenosis associated with outcome in lumbar spinal stenosis patients treated with posterior microsurgical decompression 

      Aaen, Jørn Ståle; BANITALEBI, HASAN; Austevoll, Ivar Magne; Hellum, Christian; Storheim, Kjersti; Myklebust, Tor Åge; Anvar, Masoud D; Weber, Clemens; Solberg, Tore; Grundnes, Oliver; Brisby, Helena; Indrekvam, Kari; Hermansen, Erland (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-05)
      Background We aim to investigate associations between preoperative radiological findings of lumbar foraminal stenosis with clinical outcomes after posterior microsurgical decompression in patients with predominantly central lumbar spinal stenosis (LSS).<p> <p>Methods The study was an additional analysis in the NORDSTEN Spinal Stenosis Trial. In total, 230 men and 207 women (mean age 66.8 (SD ...
    • Living with dead spaces: Closing complex posterior midline defects with midline-based perforator flaps 

      de Weerd, Louis; Solberg, Tore; Falch, Birgit Margrethe; Weum, Sven (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-01)
    • Long-Term Results After Surgery for Degenerative Cervical Myelopathy 

      Johansen, Tonje Okkenhaug; Holmberg, Siril Therese; Danielsen, Elisabet; Rao, Vidar; Salvesen, Øyvind Olav; Andresen, Hege; Carmen, Vleggeert-Lankamp; Solberg, Tore; Gulati, Sasha; Nygaard, Øystein Petter (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-20)
      BACKGROUND AND OBJECTIVES: Degenerative cervical myelopathy (DCM) is a frequent cause of spinal cord dysfunction, and surgical treatment is considered safe and effective. Long-term results after surgery are limited. This study investigated long-term clinical outcomes through data from the Norwegian registry for spine surgery.<p> <p>METHODS: Patients operated at the university hospitals serving ...
    • A nationwide study of patients operated for cervical degenerative disorders in public and private hospitals 

      Danielsen, elisabeth; Mjåset, Christer; Ingebrigtsen, Tor; Gulati, Sasha; Grotle, Margreth; Rudolfsen, Jan Håkon; Nygaard, Øystein Petter; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-27)
      During the last decades, there has been an increase in the rate of surgery for degenerative disorders of the cervical spine and in the use of supplementary private health insurance. Still, there is limited knowledge about the diferences in characteristics of patients operated in public and private hospitals. Therefore, we aimed at comparing sociodemographic-, clinical- and patient management data ...
    • Non-respondents do not bias outcome assessment after cervical spine surgery: a multicenter observational study from the Norwegian registry for spine surgery (NORspine) 

      Ingebrigtsen, Tor; Aune, Grethe; Karlsen, Martine Eriksen; Gulati, Sasha; Kolstad, Frode; Nygaard, Øystein Petter; Thyrhaug, Anette Moltu; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-21)
      Background - The Norwegian registry for spine surgery (NORspine) is a national clinical quality registry which has recorded more than 10,000 operations for degenerative conditions of the cervical spine since 2012. Registries are large observational cohorts, at risk for attrition bias. We therefore aimed to examine whether clinical outcomes differed between respondents and non-respondents to standardized ...
    • The Norwegian degenerative spondylolisthesis and spinal stenosis (NORDSTEN) study: study overview, organization structure and study population 

      Indrekvam, Kari; Bånerud, Ingrid Fjeldheim; Hermansen, Erland; Austevoll, Ivar Magne; Rekeland, Frode Gurvin; Guddal, Maren Hjelle; Solberg, Tore; Brox, Jens Ivar; Hellum, Christian; Storheim, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-03)
      Purpose To provide an overview of the The Norwegian Degenerative spondylolisthesis and spinal stenosis (NORDSTEN)- study and the organizational structure, and to evaluate the study population.<p> <p>Methods The NORDSTEN is a multicentre study with 10 year follow-up, conducted at 18 public hospitals. NORDSTEN includes three studies: (1) The randomized spinal stenosis trial comparing the impact of ...
    • The Norwegian registry for spine surgery (NORspine): cohort profile 

      Mikkelsen, Eirik; Ingebrigtsen, Tor; Thyrhaug, Anette Moltu; Olsen, Lena Ringstad; Nygaard, Øystein Petter; Austevoll, Ivar Magne; Brox, Jens Ivar; Hellum, Christian; Kolstad, Frode; Lønne, Greger; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-17)
      Purpose - To review and describe the development, methods and cohort of the lumbosacral part of the Norwegian registry for spine surgery (NORspine).<p> <p>Methods - NORspine was established in 2007. It is government funded, covers all providers and captures consecutive cases undergoing operations for degenerative disorders. Patients’ participation is voluntary and requires informed consent. A set ...
    • Open discectomy vs microdiscectomy for lumbar disc herniation - a protocol for a pragmatic comparative effectiveness study 

      Sørlie, Andreas; Gulati, Sasha; Giannadakis, Charalampis; Carlsen, Sven Magnus; Salvesen, Øyvind; Nygaard, Øystein Petter; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-02)
      Introduction:<br>Since the introduction of lumbar microdiscectomy in the 1970’s, many studies have attempted to compare the effectiveness of this method with that of standard open discectomy with conflicting results. This observational study is designed to compare the relative effectiveness of microdiscectomy (MD) with open discectomy (OD) for treating lumbar disc herniation, -within a large cohort, ...
    • Outcome prediction in chronic unilateral lumbar radiculopathy: Prospective cohort study 

      Iversen, Trond; Solberg, Tore; Wilsgaard, Tom; Waterloo, Knut; Brox, Jens Ivar; Ingebrigtsen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-07)
      Background: Identification of prognostic factors for persistent pain and disability are important for better understanding of the clinical course of chronic unilateral lumbar radiculopathy and to assist clinical decision-making. There is a lack of scientific evidence concerning prognostic factors. The aim of this study was to identify clinically relevant predictors for outcome at 52 weeks. <p>Methods: ...
    • Pain During Sex Before and After Surgery for Lumbar Disc Herniation - A Multicenter Observational Study 

      Holmberg, Siril Therese; Salvesen, Øyvind; Vangen-Lønne, Vetle; Hara, Sozaburo; Fredheim, Olav Magnus; Solberg, Tore; Jakola, Asgeir S; Solheim, Ole; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-15)
      <p>Study Design. Observational multicenter study. <p>Objective. The aim of this study was to evaluate changes in pain during sexual activity after surgery for lumbar disc herniation (LDH). <p>Summary of Background Data. There are limited data available on sexual function in patients undergoing surgery for LDH. <p>Methods. Data were retrieved from the Norwegian Registry for Spine Surgery. The ...
    • Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial 

      Hermansen, Erland; Myklebust, Tor Åge; Weber, Clemens; Brisby, Helena; Austevoll, Ivar Magne; Hellum, Christian; Storheim, Kjersti; Aaen, Jørn Ståle; BANITALEBI, HASAN; Brox, Jens Ivar; Grundnes, Oliver; Rekeland, Frode Gurvin; Solberg, Tore; Franssen, Eric; Indrekvam, Kari (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-15)
      Objective - The aim was to investigate the association between postoperative dural sac cross-sectional area (DSCA) after decompressive surgery for lumbar spinal stenosis and clinical outcome. Furthermore, to investigate if there is a minimum threshold for how extensive a posterior decompression needs to be to achieve a satisfactory clinical result.<p> <p>Summary of Background Data - There is ...
    • A prognostic model for failure and worsening after lumbar microdiscectomy: a multicenter study from the Norwegian Registry for Spine Surgery 

      Werner, David Andreas Thomas; Grotle, Margreth; Småstuen, Milada Cvancarova; Gulati, Sasha; Nygaard, Øystein Petter; Salvesen, Øyvind; Ingebrigtsen, Tor; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-10)
      <i>Objective</i> - To develop a prognostic model for failure and worsening 1 year after surgery for lumbar disc herniation.<br><br> <i>Methods</i> - This multicenter cohort study included 11,081 patients operated with lumbar microdiscectomy, registered at the Norwegian Registry for Spine Surgery. Follow-up was 1 year. Uni- and multivariate logistic regression analyses were used to assess potential ...
    • Prospects of returning to work after lumbar spine surgery for patients considering disability pension: A nationwide study based on data from the Norwegian Registry for Spine Surgery 

      Hammer, Lovise; Ingebrigtsen, Tor; Gulati, Sasha; Hara, Sozaburo; Nygaard, Øystein Petter; Hara, Karen Walseth; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-09)
      Objectives To assess the odds for not returning to work (non-RTW) 1 year after treatment among patients who had applied for or were planning to apply for disability pension (DP-applicant) prior to an operation for degenerative disorders of the lumbar spine.<p> <p>Methods This population-based cohort study from the Norwegian Registry for Spine surgery included 26 688 cases operated for ...
    • The rates of lumbar spinal stenosis surgery in Norwegian public hospitals: a threefold increase from 1999 to 2013 

      Grøvle, Lars; Fjeld, Olaf Randall; Haugen, Anne Julsrud; Helgeland, Jon; Småstuen, Milada Cvancarova; Solberg, Tore; Zwart, John-Anker; Grotle, Margreth (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-17)
      <p><i>Study Design</i>: Retrospective administrative database study.</p> <p><i>Objective</i>: To assess temporal and regional trends, and length of hospital stay, in lumbar spinal stenosis (LSS) surgery in Norwegian public hospitals from 1999 to 2013.</p> <p><i>Summary of Background Data</i>: Studies from several countries have reported increasing rates of LSS surgery over the last decades. ...
    • Return to Work after Surgery for Cervical Radiculopathy: A Nationwide Registry-based Observational Study 

      Hara, Sozaburo; Lønne, Vetle Vangen; Aasdahl, Lene; Salvesen, Øyvind Olav; Solberg, Tore; Gulati, Sasha; Hara, Karen Walseth (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-15)
      Study Design - An observational multicenter study.<p> <p>Summary of Background Data - Return to work (RTW) is increasingly used to assess the standard, benefit, and quality of health care.<p> <p>Objective - The aim of this study was to evaluate sick leave patterns among patients undergoing surgery for cervical radiculopathy and identify predictors of successful RTW using two nationwide ...