Blar i forfatter "Specht, Karsten"

Viser treff 21-34 av 34

    • A multimodal study of the effects of tDCS on dorsolateral prefrontal and temporo-parietal areas during dichotic listening 

      Marquardt, Lynn Anne; Kusztrits, Isabella; Craven, Alexander R.; Hugdahl, Kenneth; Specht, Karsten; Hirnstein, Marco (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-03)
      The underlying neural mechanisms of transcranial direct current stimulation (tDCS), especially beyond the primary motor cortex, remain unclear. Several studies examined tDCS effects on either functional activity, neurotransmitters or behavior but few investigated those aspects together to reveal how the brain responds to tDCS. The objective is to elucidate the underlying mechanisms of tDCS using a ...

    • Music for autism: a protocol for an international randomized crossover trial on music therapy for children with autism 

      Loria, Marianna Ruiz; Groessing, Alexander; Guran, Alexandrina; Koçan, Asena U.; Mikus, Nace; Nater, Urs M.; Kouwer, Karlijn; Posserud, Maj-Britt Rocio; Salomon-Gimmon, Maayan; Todorova, Boryana; Wagner, Isabella C.; Gold, Christian; Silani, Giorgia; Specht, Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-02)
      The notion of a connection between autism and music is as old as the first reported cases of autism, and music has been used as a therapeutic tool for many decades. Music therapy holds promise as an intervention for individuals with autism, harnessing their strengths in music processing to enhance communication and expression. While previous randomized controlled trials have demonstrated positive ...

    • Neuroplastic effects in patients with traumatic brain injury after music-supported therapy 

      Vik, Berit; Skeie, Geir Olve; Specht, Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
      Damage to the orbitofrontal cortex (OFC) often occurs following a traumatic brain injury (TBI) and can lead to complex behavioral changes, including difficulty with attention and concentration. We investigated the effects of musical training on patients with behavioral and cognitive deficits following a mild traumatic brain injury (mTBI) and found significant functional neuro-plastic changes in the ...

    • Physical exercise augmented cognitive behaviour therapy for older adults with generalised anxiety disorder (PEXACOG): a feasibility study for a randomized controlled trial 

      Sirevåg, Kristine; Stavestrand, Silje Haukenes; Sjøbø, Trond; Endal, Trygve Bruun; Nordahl, Hans Morten; Andersson, E.; Nordhus, Inger Hilde; Rekdal, Åsa Kristine; Specht, Karsten; Hammar, Åsa Karin; Halmøy, Anne; Mohlman, J.; Hjelmervik, Helene; Thayer, Julian Francis; Hovland, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-19)
      Background Generalised anxiety disorder (GAD) is a frequent and severe disorder among older adults. For older adults with GAD the effect of the recommended treatment, cognitive behaviour therapy (CBT), is reduced. Physical exercise (PE) may enhance the effect of CBT by improving cognitive function and increasing levels of brain-derived neurotrophic factor (BDNF), a predictor of the effect of CBT ...

    • Pilot-RCT Finds No Evidence for Modulation of Neuronal Networks of Auditory Hallucinations by Transcranial Direct Current Stimulation 

      Marquardt, Lynn Anne; Craven, Alexander R.; Hugdahl, Kenneth Jan; Johnsen, Erik; Kroken, Rune Andreas; Kusztrits, Isabella; Specht, Karsten; Thomassen, Anne Synnøve; Weber, Sarah; Hirnstein, Marco (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-12)
      Background: Transcranial direct current stimulation (tDCS) is used as treatment for auditory verbal hallucinations (AVH). The theory behind the treatment is that tDCS increases activity in prefrontal cognitive control areas, which are assumed to be hypoactive, and simultaneously decreases activity in temporal speech perception areas, which are assumed to be hyperactive during AVH. We tested this ...

    • Reduced grey matter volume in frontal and temporal areas in depression: Contributions from voxel-based morphometry study 

      Kandilarova, Sevdalina; Stoyanov, Drozdstoy; Sirakov, Nickolay; Maes, Michael; Specht, Karsten (Journal article; Tidsskriftartikkel, 2019-06-25)
      <i>Objective</i>: The aim of the current study was to examine whether and to what extent mood disorders, comprising major depression and bipolar disorder, are accompanied by structural changes in the brain as measured using voxel-based morphometry (VBM).<p> <p><i>Methods</i>: We performed a VBM study using a 3Т MRI system (GE Discovery 750w) in patients with mood disorders (n=50), namely, 39 with ...

    • Reduced grey- and white matter volumes due to unilateral hearing loss following treatment for vestibular schwannoma 

      Heggdal, Peder Olaf Laugen; Larsen, Kristina S.; Brännström, Jonas; Aarstad, Hans Jørgen; Specht, Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-03)
      <i>Objective</i> - Previous studies of the consequences of unilateral hearing loss (UHL) on the functional-structural organization of the brain has included subjects with various degrees of UHL. We suggest that the consequences of a total loss of hearing in one ear might differ from those seen in subjects with residual hearing in the affected ear. Thus, the main aim of the present study was to compare ...

    • The Role of Depth Perception in XR from a Neuroscience Perspective: A Primer and Survey 

      Hushagen, Vetle; Tresselt, Gustav; Smit, Noeska Natasja; Specht, Karsten (Journal article; Tidsskriftartikkel, 2021-09-21)
      Augmented and virtual reality (XR) are potentially powerful tools for enhancing the efficiency of interactive visualization of complex data in biology and medicine. The benefits of visualization of digital objects in XR mainly arise from enhanced depth perception due to the stereoscopic nature of XR head mounted devices. With the added depth dimension, XR is in a prime position to convey complex ...

    • Sex- and sex hormone-related variations in energy-metabolic frontal brain asymmetries: A magnetic resonance spectroscopy study 

      Hjelmervik, Helene; Hausmann, Markus; Craven, Alexander R.; Hirnstein, Marco; Hugdahl, Kenneth; Specht, Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-31)
      Creatine is a key regulator of brain energy homeostasis, and well-balanced creatine metabolism is central in healthy brain functioning. Still, the variability of brain creatine metabolism is largely unattended in magnetic resonance spectroscopy (MRS) research. In the human brain, marginal sex differences in creatine levels have been found in the prefrontal cortex. It is however not known to ...

    • Subjective judgments of rhythmic complexity in Parkinson's disease: Higher baseline, preserved relative ability, and modulated by tempo 

      Vikene, Kjetil; Skeie, Geir Olve; Specht, Karsten (Journal article; Peer reviewed, 2019-09-03)
      Previous research has demonstrated that people with Parkinson’s disease (PD) have difficulties with the perceptual discrimination of rhythms, relative to healthy controls. It is not however clear if this applies only to simpler rhythms (a so called “beat-based” deficit), or if it is a more generalized deficit that also applies to more complex rhythms. Further insight into how people with PD process ...

    • Suppression, Maintenance, and Surprise: Neuronal Correlates of Predictive Processing Specialization for Musical Rhythm 

      Færøvik, Ulvhild; Specht, Karsten; Vikene, Kjetil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-27)
      Auditory repetition suppression and omission activation are opposite neural phenomena and manifestations of principles of predictive processing. Repetition suppression describes the temporal decrease in neural activity when a stimulus is constant or repeated in an expected temporal fashion; omission activity is the transient increase in neural activity when a stimulus is temporarily and unexpectedly ...

    • Time of day dependent longitudinal changes in resting-state fMRI 

      Vaisvilaite, Liucija; Andersson, Micael; Salami, Alireza; Specht, Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-05)
      Longitudinal studies have become more common in the past years due to their superiority over cross-sectional samples. In light of the ongoing replication crisis, the factors that may introduce variability in resting-state networks have been widely debated. This publication aimed to address the potential sources of variability, namely, time of day, sex, and age, in longitudinal studies within ...

    • Time-of-Day Effects in Resting-State Functional Magnetic Resonance Imaging: Changes in Effective Connectivity and Blood Oxygenation Level Dependent Signal 

      Vaisvilaite, Liucija; Hushagen, Vetle; Grønli, Janne; Specht, Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-29)
      Introduction: In the light of the ongoing replication crisis in the field of neuroimaging, it is necessary to assess the possible exogenous and endogenous factors that may affect functional magnetic resonance imaging (fMRI). The current project investigated time-of-day effects in the spontaneous fluctuations (<0.1 Hz) of the blood oxygenation level dependent (BOLD) signal.<p> <p>Method: Using ...

    • Variability in Resting-State Functional Magnetic Resonance Imaging: The Effect of Body Mass, Blood Pressure, Hematocrit, and Glycated Hemoglobin on Hemodynamic and Neuronal Parameters 

      Sjuls, Guro Stensby; Specht, Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-13)
      Introduction: Replicability has become an increasing focus within the scientific communities with the ongoing ‘‘replication crisis.’’ One area that appears to struggle with unreliable results is resting-state functional magnetic resonance imaging (rs-fMRI). Therefore, the current study aimed at improving the knowledge of endogenous factors that contribute to inter-individual variability. Methods: ...