• Effectiveness of heterologous ChAdOx1 nCoV-19 and mRNA prime-boost vaccination against symptomatic Covid-19 infection in Sweden: A nationwide cohort study 

      Nordström, Peter; Ballin, Marcel; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background - The effectiveness of heterologous prime-boost Coronavirus disease 2019 (Covid-19) vaccination is currently unknown.<p> <p>Methods - From individuals vaccinated with two doses against Covid-19 in Sweden until July 5, 2021 (N=3,445,061), we formed a study cohort including 94,569 individuals that had received heterologous ChAdOx1 nCoV-19 / BNT162b2 prime-boost vaccination, 16,402 ...
    • Effects of interval training on quality of life and cardiometabolic risk markers in older adults: a randomized controlled trial 

      Ballin, Marcel; Lundberg, Emmy; Sörlén, Niklas; Nordström, Peter; Hult, Andreas; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-04)
      <i>Purpose</i>: To explore the effects of 10 weeks of progressive vigorous interval training as a single intervention on health-related quality of life (HRQoL) and cardiometabolic risk markers in centrally obese 70-year-old individuals.<p><p> <i>Participants and methods</i>: A randomized controlled trial (ClinicalTrials.gov registration no. NCT03450655) including seventy-seven community-dwelling ...
    • Effects of Resistance Training on Functional Strength and Muscle Mass in 70-Year-Old Individuals With Pre-sarcopenia: A Randomized Controlled Trial 

      Vikberg, Sanna; Sorlen, Niklas; Branden, Lisa; Johansson, Jonas; Nordström, Anna Hava; Hult, Andreas; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-07)
      Objective: Sarcopenia has been defined as age-related loss of muscle mass and function. The aim of this randomized controlled trial was to examine the effects of a 10-week instructor-led resistance training program on functional strength and body composition in men and women aged 70 years with presarcopenia. Design, Setting, and Participants: Participants were randomized to either 10 weeks of a ...
    • Epidemiology of osteonecrosis among older adults in Sweden 

      Bergman, Jonathan; Nordström, Anna Hava; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-09)
      <p><i>Summary - </i>This study estimated the incidence of osteonecrosis in a Swedish, nationwide cohort of older adults. Osteonecrosis was approximately 10 times more common than in previous studies. The strongest risk factors were dialysis, hip fracture, osteomyelitis, and organ transplantation, but only hip fractures could have contributed substantially to the disease burden. <p><i>Introduction ...
    • Excess Mortality After COVID-19 in Swedish Long-Term Care Facilities 

      Ballin, Marcel; Bergman, J.; Kivipelto, M; Nordström, Anna Hava; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-24)
      Objective - To compare 30-day mortality in long-term care facility (LTCF) residents with and without COVID-19 and to investigate the impact of 31 potential risk factors for mortality in COVID-19 cases.<p> <p>Design - Retrospective cohort study.<p> <p>Setting and Participants - All residents of LTCFs registered in Senior Alert, a Swedish national database of health examinations in older adults, ...
    • Feasibility of an Online Delivered, Home-Based Resistance Training Program for Older Adults – A Mixed Methods Approach 

      Vikberg, Sanna; Björk, Sabine; Nordström, Anna Hava; Nordström, Peter; Hult, Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-03)
      Background: Physical inactivity and low muscle mass are risk factors for falls, fractures and overall poor health. However, physical activity is reduced with increased age and only a fraction of older adults engages in resistance training (RT). Thus, strategies that facilitate RT among older adults are needed. The aim of the present study was to evaluate the effectiveness and user experience, ...
    • Genetic and Environmental Factors and Cardiovascular Disease Risk in Adolescents 

      Ballin, Marcel; Neovius, Martin; Ortega, Francisco B.; Henriksson, Pontus; Nordström, Anna Hava; Berglind, Daniel; Nordström, Peter; Ahlqvist, Viktor H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-17)
      Importance - Cardiovascular risk factors in youth have been associated with future cardiovascular disease (CVD), but conventional observational studies are vulnerable to genetic and environmental confounding.<p> <p>Objective - To examine the role of genetic and environmental factors shared by full siblings in the association of adolescent cardiovascular risk factors with future CVD.<p> <p>Design, ...
    • Impact of exercise interventions on physical fitness in breast cancer patients and survivors: a systematic review 

      Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-12)
      Background - This systematic review aims to identify the effects of exercise interventions in patients with breast cancer (BCP) and survivors (BCS) on selected variables of physical fitness.<p> <p>Methods - A comprehensive literature search was conducted using Medline and Scopus. Randomized controlled trials with isolated exercise interventions in BCP and BCS women (< 5 years from therapy completion) ...
    • Injuries in Swedish floorball players: A nationwide matched cohort study. 

      Tervo, T.; Nyström, H; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-07)
      The aim of this study was to investigate injury incidence and patterns in female and male floorball players of different ages compared with matched controls. This study involved all floorball players in Sweden and licensed during 2010–2012, and matched controls selected from Sweden’s Total Population Register. Injury diagnoses were acquired from national health care registers. The cohort comprised ...
    • Mid-calf skeletal muscle density and its associations with physical activity, bone health and incident 12-month falls in older adults: The Healthy Ageing Initiative 

      Scott, David; Johansson, Jonas; McMillan, Lachlan; Ebeling, Peter R; Nordström, Anna Hava; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-08)
      <i>Background</i> - Lower skeletal muscle density, indicating greater infiltration of adipose tissue into muscles, is associated with higher fracture risk in older adults. We aimed to determine whether mid-calf muscle density is associated with falls risk and bone health in community-dwelling older adults.<p><p> <i>Methods</i> - 2214 community-dwelling men and women who participated in the ...
    • Older Adults’ Experiences With Using Wearable Devices: Qualitative Systematic Review and Meta-synthesis 

      Moore, Kevin; O'Shea, Emma; Kenny, Lorna; Barton, John; Tedesco, Salvatore; Sica, Marco; Crowe, Colum; Alamäki, Antti; Condell, Joan; Nordström, Anna Hava; Timmons, Suzanne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-03)
      Background: Older adults may use wearable devices for various reasons, ranging from monitoring clinically relevant health metrics or detecting falls to monitoring physical activity. Little is known about how this population engages with wearable devices, and no qualitative synthesis exists to describe their shared experiences with long-term use.<p> Objective: This study aims to synthesize qualitative ...
    • Prospective Association of Daily Steps with Cardiovascular Disease: A Harmonized Meta-Analysis 

      Paluch, Amanda E.; Bajpai, Shivangi; Ballin, Marcel; Bassett, David R.; Buford, Thomas W.; Carnethon, Mercedes R.; Chernofsky, Ariel; Dooley, Erin E.; Ekelund, Ulf; Evenson, Kelly R.; Galuska, Deborah A.; Jefferis, Barbara J.; Kong, Lingsong; Kraus, William E.; Larson, Martin G.; Lee, I-Min; Matthews, Charles E.; Newton, Robert L.; Nordström, Anna Hava; Nordström, Peter; Palta, Priya; Patel, Alpa V.; Pettee Gabriel, Kelley; Pieper, Carl F.; Pompeii, Lisa; Rees-Punia, Erika; Spartano, Nicole L.; Vasan, Ramachandran S.; Whincup, Peter H.; Yang, Shengping; Fulton, Janet E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-20)
      Background: Taking fewer than the widely promoted “10 000 steps per day” has recently been associated with lower risk of all-cause mortality. The relationship of steps and cardiovascular disease (CVD) risk remains poorly described. A meta-analysis examining the dose–response relationship between steps per day and CVD can help inform clinical and public health guidelines. Methods: Eight prospective ...
    • Recommendations for initial examination, differential diagnosis, and management of concussion and other head injuries in high-level football 

      Feddermann-Demont, Nina; Chiampas, Georges; Cowie, Charlotte; Meyer, T.; Nordström, Anna Hava; Putukian, Margot; Straumann, Dominik; Kramer, Efraim (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-17)
      Head injuries can result in substantially different outcomes, ranging from no detectable effect to transient functional impairments to life‐threatening structural lesions. In high‐level international football (soccer) tournaments, on average, one head injury occurs in every third match. Making the diagnosis and determining the severity of a head injury immediately on‐pitch or off‐field is a major ...
    • Risk Factors for COVID-19 Diagnosis, Hospitalization, and Subsequent All-Cause Mortality in Sweden: A Nationwide Study 

      Nordström, Peter; Berggren, J.; Ballin, Marcel; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-11)
      We conducted a nationwide, registry-based study to investigate the importance of 34 potential risk factors for coronavirus disease 2019 (COVID-19) diagnosis, hospitalization (with or without intensive care unit [ICU] admission), and subsequent all-cause mortality. The study population comprised all COVID-19 cases confirmed in Sweden by mid-September 2020 (68,575 non-hospitalized, 2494 ICU hospitalized, ...
    • Risk Factors for COVID-19 Diagnosis, Hospitalization, and Subsequent All-Cause Mortality in Sweden: A Nationwide Study. 

      Bergman, Jonathan; Ballin, Marcel; Nordström, Anna Hava; Nordstrom, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-11)
      We conducted a nationwide, registry-based study to investigate the importance of 34 potential risk factors for coronavirus disease 2019 (COVID-19) diagnosis, hospitalization (with or without intensive care unit [ICU] admission), and subsequent all-cause mortality. The study population comprised all COVID-19 cases confirmed in Sweden by mid-September 2020 (68,575 non-hospitalized, 2494 ICU hospitalized, ...
    • Self-reported protein intake and properties of bone in community-dwelling older individuals 

      Johansson, Jonas; Hult, Andreas; Morseth, Bente; Nordström, Anna Hava; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-31)
      Summary This study revealed that a quick and simple estimation of protein intake was related to measures of bone density and area in 70-year-old individuals. Furthermore, these associations were mediated by muscle mass when investigating peripheral measurement sites such as arms and legs.<p> <p>Purpose Recent evidence suggests that dietary protein is beneficial for bone health in older individuals, ...
    • Time-varying risk of death after SARS-CoV-2 infection in Swedish long-term care facility residents: a matched cohort study 

      Ballin, Marcel; Ioannidis, John P.; Bergman, Jonathan; Kivipelto, M; Nordström, Anna Hava; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-24)
      Objectives - To evaluate whether SARS-CoV-2 infection in residents of long-term care (LTC) facilities is associated with higher mortality after the acute phase of infection, and to estimate survival in uninfected residents.<p> <p>Design - Extended follow-up of a previous, propensity score-matched, retrospective cohort study based on the Swedish Senior Alert register.<p> <p>Setting - LTC ...
    • Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study 

      Nordström, Anna Hava; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-30)
      Background<p> <p>Traumatic brain injury (TBI) has been associated with dementia. The questions of whether the risk of dementia decreases over time after TBI, whether it is similar for different TBI types, and whether it is influenced by familial aggregation are not well studied. <p>Methods and findings <p>The cohort considered for inclusion comprised all individuals in Sweden aged 50 years ...
    • Use of short-acting and long-acting hypnotics and the risk of fracture: a critical analysis of associations in a nationwide cohort 

      Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-30)
      <p><i>Summary - </i>Numerous observational studies suggest that hypnotics increase the risk of fractures, and long-acting hypnotics are suggested to be especially harmful. This study showed that the highest risk of fracture was found before start of treatment and remained after end of therapy, suggesting that the increased risk during treatment is influenced by other factors, such as underlying ...
    • Web-based exercise versus supervised exercise for decreasing visceral adipose tissue in older adults with central obesity: A randomized controlled trial 

      Ballin, Marcel; Hult, Andreas; Björk, Sabine; Lundberg, Emmy; Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-12)
      <i>Background</i> - Visceral adipose tissue (VAT) is a strong risk factor for cardiovascular disease and increases with age. While supervised exercise (SE) may be an effective approach, web-based exercise (WE) have other advantages such as being more readily accessible. Therefore, we evaluated the effects of WE on VAT, body composition and cardiometabolic risk markers in centrally obese older adults ...