• 

  The effect of trauma and alcohol on the relationship between level of cytokines and depression among patients entering psychiatric treatment 

  Toft, Helge Prytz; Neupane, Sudan Prasad; Bramness, Jørgen Gustav; Tilden, Terje; Wampold, Bruce E.; Lien, Lars (Journal article; Peer reviewed, 2018-04-10)

  <b>Background</b><br> Depression is associated with immunological responses as reflected by altered levels of circulating cytokines. Alcohol use and trauma may modulate immune activity, and few studies have investigated these factors in depressed patients. We aimed to explore the association between circulating peripheral cytokine levels and degree of depressive symptoms, taking trauma and alcohol ...
• 

  Receptor activator of nuclear factor kB ligand, osteoprotegerin, and risk of death following a breast cancer diagnosis: results from the EPIC cohort 

  Sarink, Danja; Schock, Helena; Johnson, Theron; Chang-Claude, Jenny; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Fournier, Agnès; Kvaskoff, Marina; Boeing, Heiner; Karakatsani, Anna; Trichopoulou, Antonia; La Vecchia, Carlo; Masala, Giovanna; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; van Gils, Carla H.; Peeters, Petra H.M.; Weiderpass, Elisabete; Agudo, Antonio; Rodríguez-Barranco, Miguel; Huerta, José María; Ardanaz, Eva; Gil, Leire; Kaw, Kay Tee; Schmidt, Julie A.; Dossus, Laure; His, Mathilde; Aune, Dagfinn; Riboli, Elio; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Peer reviewed, 2018-10-22)

  <b>Background</b><br> Receptor activator of nuclear factor kappa-B (RANK)-signaling is involved in tumor growth and spread in experimental models. Binding of RANK ligand (RANKL) to RANK activates signaling, which is inhibited by osteoprotegerin (OPG). We have previously shown that circulating soluble RANKL (sRANKL) and OPG are associated with breast cancer risk. Here we extend these findings to ...
• 

  Scalable exploration of population-scale drug consumption data 

  Skar, Tengel Ekrem (Master thesis; Mastergradsoppgave, 2019-06-01)

  The potential for knowledge discovery is currently underutilized on pharmacoepidemiologic data sets. A big dataset enables finding and assessing rare drug consumption patterns that are associated with adverse drug reactions causing hospitalization, or death. To enable such exploration of big pharmacoepidemiology data, four key issues need so be addressed. First, to ingest, transform, preprocess ...
• 

  Latency Optimized Microservice Architecture for Privacy Preserving Computing 

  Magnussen, Nikolai Åsen (Master thesis; Mastergradsoppgave, 2019-06-01)

  Recent developments in microservices architecture and building have lead to the advent of unikernels, a specialized operating system kernel coupled with, and executing only, a single application. This thesis presents PPCE a distributed system utilising a microservices architecture based on unikernels, created to enable privacy-preserving computing for users, classes of users, and more importantly; ...
• 

  “Then I went to a hospital abroad”: acknowledging implications of stakeholders’ differing risk understandings related to use of complementary and alternative medicine in European health care contexts 

  Salamonsen, Anita; Wiesener, Solveig (Journal article; Peer reviewed, 2019-04-30)

  <b>Background</b><br> Complementary and alternative medicine (CAM) is a rather novel issue within public healthcare and health policy-making. CAM use in Europe is widespread, patient-initiated, and patient-evaluated, and the regulation across countries has been evaluated as disharmonized. CAM users are left in an uncertain position, and patient safety may be threatened. How “risk” is understood by ...

View more