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  Ocean acidification at a coastal CO2 vent induces expression of stress-related transcripts and transposable elements in the sea anemone Anemonia viridis 

  Urbarova, Ilona; Forêt, Sylvain; Dahl, Mikael Per; Emblem, Åse E.; Milazzo, Marco; Hall-Spencer, Jason M.; Johansen, Steinar Daae (Journal article; Peer reviewed, 2019-05-08)

  Ocean acidification threatens to disrupt interactions between organisms throughout marine ecosystems. The diversity of reef-building organisms decreases as seawater CO2 increases along natural gradients, yet soft-bodied animals, such as sea anemones, are often resilient. We sequenced the polyA-enriched transcriptome of adult sea anemone Anemonia viridis and its dinoflagellate symbiont sampled along ...
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  The effect of trauma and alcohol on the relationship between level of cytokines and depression among patients entering psychiatric treatment 

  Toft, Helge Prytz; Neupane, Sudan Prasad; Bramness, Jørgen Gustav; Tilden, Terje; Wampold, Bruce E.; Lien, Lars (Journal article; Peer reviewed, 2018-04-10)

  <b>Background</b><br> Depression is associated with immunological responses as reflected by altered levels of circulating cytokines. Alcohol use and trauma may modulate immune activity, and few studies have investigated these factors in depressed patients. We aimed to explore the association between circulating peripheral cytokine levels and degree of depressive symptoms, taking trauma and alcohol ...
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  Receptor activator of nuclear factor kB ligand, osteoprotegerin, and risk of death following a breast cancer diagnosis: results from the EPIC cohort 

  Sarink, Danja; Schock, Helena; Johnson, Theron; Chang-Claude, Jenny; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Fournier, Agnès; Kvaskoff, Marina; Boeing, Heiner; Karakatsani, Anna; Trichopoulou, Antonia; La Vecchia, Carlo; Masala, Giovanna; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; van Gils, Carla H.; Peeters, Petra H.M.; Weiderpass, Elisabete; Agudo, Antonio; Rodríguez-Barranco, Miguel; Huerta, José María; Ardanaz, Eva; Gil, Leire; Kaw, Kay Tee; Schmidt, Julie A.; Dossus, Laure; His, Mathilde; Aune, Dagfinn; Riboli, Elio; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Peer reviewed, 2018-10-22)

  <b>Background</b><br> Receptor activator of nuclear factor kappa-B (RANK)-signaling is involved in tumor growth and spread in experimental models. Binding of RANK ligand (RANKL) to RANK activates signaling, which is inhibited by osteoprotegerin (OPG). We have previously shown that circulating soluble RANKL (sRANKL) and OPG are associated with breast cancer risk. Here we extend these findings to ...
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  Scalable exploration of population-scale drug consumption data 

  Skar, Tengel Ekrem (Master thesis; Mastergradsoppgave, 2019-06-01)

  The potential for knowledge discovery is currently underutilized on pharmacoepidemiologic data sets. A big dataset enables finding and assessing rare drug consumption patterns that are associated with adverse drug reactions causing hospitalization, or death. To enable such exploration of big pharmacoepidemiology data, four key issues need so be addressed. First, to ingest, transform, preprocess ...
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  Latency Optimized Microservice Architecture for Privacy Preserving Computing 

  Magnussen, Nikolai Åsen (Master thesis; Mastergradsoppgave, 2019-06-01)

  Recent developments in microservices architecture and building have lead to the advent of unikernels, a specialized operating system kernel coupled with, and executing only, a single application. This thesis presents PPCE a distributed system utilising a microservices architecture based on unikernels, created to enable privacy-preserving computing for users, classes of users, and more importantly; ...

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