• Traveling ionospheric disturbances and ionospheric perturbations associated with solar flares in September 2017 

    Zhang, Shun-Rong; Coster, Anthea; Erickson, Philip j.; Goncharenko, Larisa; Rideout, William; Vierinen, Juha (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-10)
    Solar flares provide strong impulsive radiation and energy injection to the sunlit upper atmosphere. The impact on the ionosphere is immense in spatial scale, and therefore, it is not immediately evident if dramatically elevated neutral heating can lead to excitation of acoustic gravity waves. Using primary observations from Global Navigation Satellite System differential TEC (total electron ...
  • Discontinuity in the molecular neuroendocrine response to increasing daylengths in Ile-de-France ewes: Is transient Dio2 induction a key feature of circannual timing? 

    Dardente, Hugues; Lomet, Didier; Chesneau, Didier; Pellicer-Rubio, Maria-Teresa; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-24)
    In mammals, melatonin is responsible for the synchronisation of seasonal cycles to the solar year. Melatonin is secreted by the pineal gland with a profile reflecting the duration of the night and acts via the pituitary pars tuberalis (PT), which in turn modulates hypothalamic thyroid hormone status via seasonal changes in the production of locally‐acting thyrotrophin. Recently, we demonstrated that, ...
  • Radiosynthesis and biological investigation of a novel fluorine-18 labeled benzoimidazotriazine- based radioligand for the imaging of phosphodiesterase 2A with positron emission tomography 

    Ritawidya, Rien; Wenzel, Barbara; Teodoro, Rodrigo; Toussaint, Magali; Kranz, Mathias; Deuther-Conrad, Winnie; Dukić-Stefanović, Sladjana; Ludwig, Friedrich-Alexander; Scheunemann, Matthias; Brust, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-15)
    A specific radioligand for the imaging of cyclic nucleotide phosphodiesterase 2A (PDE2A) via positron emission tomography (PET) would be helpful for research on the physiology and disease-related changes in the expression of this enzyme in the brain. In this report, the radiosynthesis of a novel PDE2A radioligand and the subsequent biological evaluation were described. Our prospective compound ...
  • C-X-C ligand 16 is an independent predictor of cardiovascular death and morbidity in acute coronary syndromes 

    Andersen, Thomas; Ueland, Thor; Ghukasyan Lakic, Tatevik; Åkerblom, Axel; Bertilsson, Maria; Aukrust, Pål; Michelsen, Annika E; James, Stefan K.; Becker, Richard C.; Storey, Robert F.; Wallentin, Lars; Siegbahn, Agneta; Kontny, Frederic (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-26)
    <i>Objective:</i> - The chemokine CXCL16 (C-X-C motif ligand 16) is a scavenger receptor for OxLDL (oxidized low-density lipoproteins) and involved in inflammation at sites of atherosclerosis. This study aimed to investigate the association of CXCL16 with clinical outcome in patients with acute coronary syndrome.<p> <p><i>Approach and Results:</i> - Serial measurements of CXCL16 were performed ...
  • Geomorphology and development of a high-latitude channel system: the INBIS channel case (NW Barents Sea, Arctic) 

    Rui, L.; Rebesco, M.; Casamor, J.L.; Laberg, Jan Sverre; Rydningen, Tom Arne; Caburlotto, A.; Forwick, Matthias; Urgeles, R.; Accettella, D.; Lucchi, R. G.; Delbono, I.; Barsanti, M.; Demarte, M.; Ivaldi, R. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-25)
    The INBIS (Interfan Bear Island and Storfjorden) channel system is a rare example of a deep-sea channel on a glaciated margin. The system is located between two trough mouth fans (TMFs) on the continental slope of the NW Barents Sea: the Bear Island and the Storfjorden–Kveithola TMFs. New bathymetric data in the upper part of this channel system show a series of gullies that incise the shelf break ...

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