The dispatch schedule of the electrical power plant units is the result of the solution to the unit commitment optimisation problem, and it minimises the cost of production considering pre-defined technical limits. The security-constrained unit commitment problem has been defined as including the network constraints in the previously mentioned optimisation problem to obtain a feasible power system ...

To respond to the call for broader ways to understand academic engagement in sustainable tourism, I conceptualized a relational practice-based approach, termed cross-community enactive research. Relying on central ideas from the enactive research approach by entrepreneurship scholar Bengt Johannisson, which draws on autoethnography and action research, and the communities of practice theory by ...

The social networking site Instagram provides users with an abundance of photos and information in many domains including sports. The posts are often intended to inspire and motivate users. We argue that the display of success and failure of professional athletes may influence elite athletes’ own sports ambitions. Research has shown that exposure to positive ingroup stereotypes and exposure to ...

Extracellular signal-regulated kinase 3 (ERK3) is a poorly characterized member of the mitogen-activated protein (MAP) kinase family. Functional analysis of the ERK3 signaling pathway has been hampered by a lack of knowledge about the substrates and downstream effectors of the kinase. Here, we used large-scale quantitative phosphoproteomics and targeted gene silencing to identify direct ERK3 substrates ...

<p><i>Introduction:</i> Early markers of neurodegeneration provide an opportunity to detect, monitor, and initiate interventions in individuals who have an increased risk of developing dementia. Here, we investigated whether the Timed Up and Go (TUG) test is associated with early brain neurodegeneration and whether the TUG test could be a marker of cognitive decline in people with subjective cognitive ...

<p><i>Background:</i> Although colonoscopy is widely used as a screening test to detect colorectal cancer, its effect on the risks of colorectal cancer and related death is unclear. <p><i>Methods:</i> We performed a pragmatic, randomized trial involving presumptively healthy men and women 55 to 64 years of age drawn from population registries in Poland, Norway, Sweden, and the Netherlands between ...

Objective. To evaluate the feasibility of using a mobile app to collect health-related data and the impact of this data collection method on the results obtained, using the COVID-19 vaccination attitude assessment as an example. Material and methods. A survey was conducted on attitudes towards COVID-19 vaccination using the «Know Your Heart» mobile app. A total of 1,770 Arkhangelsk region residents ...

<p><i>Background:</i> Venous thromboembolism (VTE) is a life-threatening vascular event with environmental and genetic determinants. Recent VTE genome-wide association studies (GWAS) meta-analyses involved nearly 30 000 VTE cases and identified up to 40 genetic loci associated with VTE risk, including loci not previously suspected to play a role in hemostasis. The aim of our research was to expand ...

<p><i>Background</i> Nearly half of patients with hidradenitis suppurativa (HS) report dissatisfaction with their treatment. However, factors related to treatment satisfaction have not been explored. <p><i>Objectives</i> To measure associations between treatment satisfaction and clinical and treatment‐related characteristics among patients with HS. <p><i>Methods</i> Treatment satisfaction was ...

<p><i>Background/aims</i> To investigate the association of commonly used systemic medications with prevalent age-related macular degeneration (AMD) in the general population. <p><i>Methods</i> We included 38 694 adults from 14 population-based and hospital-based studies from the European Eye Epidemiology consortium. We examined associations between the use of systemic medications and any prevalent ...