Now showing items 1-20 of 34004

    • A case control study of the relationship between persistent serum creatine kinase elevation and polyneuropathy 

      Bekkelund, Svein Ivar; Abeler, Karin Louise; Lilleng, Hallvard; Løseth, Sissel (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-15)
      Creatine kinase (CK) has been associated with neuropathy, but the mechanisms are uncertain. We hypothesized that peripheral nerve function is impaired in subjects with persistent CK elevation (hyperCKemia) compared to age- and sex matched controls in a general population. The participants were recruited from the population based Tromsø study in Norway. Neuropathy impairment score (NIS), nerve ...
    • Activity-based protein profiling of serine hydrolases and penicillin-binding proteins in Enterococcus faecium 

      Grunnvåg, Jeanette Slettnes; Hegstad, Kristin; Lentz, Christian Stephan (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-15)
      Enterococcus faecium is a gut commensal bacterium which is gaining increasing relevance as an opportunistic, nosocomial pathogen. Its high level of intrinsic and acquired antimicrobial resistance is causing a lack of treatment options, particularly for infections with vancomycin-resistant strains, and prioritizes the identification and functional validation of novel druggable targets. Here, we ...
    • Ice-free period too long for Southern and Western Hudson Bay polar bear populations if global warming exceeds 1.6 to 2.6 °C 

      Stroeve, Julienne; Crawford, Alex; Ferguson, Steve; Stirling, Ian; Archer, Louise; York, Geoffrey; Babb, David; Mallett, Robbie David Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-13)
      Hudson Bay has warmed over 1 °C in the last 30 years. Coincident with this warming, seasonal patterns have shifted, with the spring sea ice melting earlier and the fall freeze-up occurring later, leading to a month longer of ice-free conditions. This extended ice-free period presents a significant challenge for polar bears, as it restricts their hunting opportunities for seals and their ability ...
    • Exploring the impact of pharmacist-supported medication reviews in dementia care: experiences of general practitioners and nurses 

      Carlqvist, Catharina; Ekstedt, Mirjam; Lehnbom, Elin Christina (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-14)
      Background Dementia is a major global public health challenge, and with the growing elderly population, its prevalence is expected to increase in the coming years. In Sweden, municipalities are responsible for providing special housing for the elderly (SÄBO), which offers services and care for older individuals needing specific support. SÄBO is both the person´s home and a care environment and ...
    • The effect of sham acupuncture can differ depending on the points needled in knee osteoarthritis: A systematic review and network meta-analysis 

      Lee, Boram; Kwon, Chan-Young; Lee, Hye Won; Nielsen, Arya; Wieland, L Susan; Kim, Tae-Hun; Birch, Stephen; Alræk, Terje; Lee, Myeong Soo (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-07)
      Objective: In sham acupuncture-controlled acupuncture clinical trials, although sham acupuncture techniques are different from those of verum acupuncture, the same acupuncture points are often used for verum and sham acupuncture, raising the question of whether sham acupuncture is an appropriate placebo. We aimed to examine the effects of sham and verum acupuncture according to the points ...
    • The Eurasian Arctic Ocean along the MOSAiC drift in 2019–2020: An interdisciplinary perspective on physical properties and processes 

      Schulz, Kirstin; Koenig, Zoe Charlotte; Muilwijk, Morven; Bauch, Dorotea; Hoppe, Clara J.M.; Droste, Elise S.; Hoppmann, Mario; Chamberlain, Emelia J.; Laukert, Georgi; Stanton, Tim; Quintanilla-Zurita, Alejandra; Fer, Ilker; Heuzé, Céline; Karam, Salar; Mieruch-Schnülle, Sebastian; Baumann, Till Martin; Vredenborg, Myriel; Tippenhauer, Sandra; Granskog, Mats (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-05)
      The Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC, 2019–2020), a year-long drift with the Arctic sea ice, has provided the scientific community with an unprecedented, multidisciplinary dataset from the Eurasian Arctic Ocean, covering high atmosphere to deep ocean across all seasons. However, the heterogeneity of data and the superposition of spatial and temporal ...
    • Home-based postnatal care following early hospital discharge: a descriptive study of the Midwife Home care programme 

      Skarsgaard, Benedikte Kjetland; Henriksen, Therese Harvold; Dahlberg, Unn; Løvvik, Tone Shetelig; Aune, Ingvild (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-23)
      Objective: At St. Olav’s University Hospital in Trondheim, Norway, “Midwife Home” (MH) is an integrated homebased postnatal service for mothers who want early discharge (i.e. 6–24 h) after giving birth. The purpose of our study was to evaluate MH by (1) describing the characteristics of mother–newborn pairs followed up by MH to investigate whether the service has an appropriate target group; (2) ...
    • The fatty liver index and risk of incident venous thromboembolism: the Tromsø Study 

      Scheres, Luuk J.J.; Brækkan, Sigrid Kufaas; Verlaan, Judith P.L.; Cannegieter, Suzanne C.; Hansen, John Bjarne; Morelli, Vania Maris (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-20)
      Background: For the relationship between obesity and venous thromboembolism (VTE), nonalcoholic fatty liver disease (recently termed metabolic dysfunction– associated steatotic liver disease) is of interest given the hepatic role in hemostasis.<p> <p>Objectives: We aimed to assess the association between the fatty liver index (FLI), as a proxy for nonalcoholic fatty liver disease, and VTE risk ...
    • Impact of cell lysis treatment before saliva metagenomic DNA extraction on the oral microbiome and the associated resistome 

      Tansirichaiya, Supathep; Songsomboon, Kittikun; Chaianant, Nichamon; Lertsivawinyu, Wasawat; Al-Haroni, Mohammed Hasan Hussein (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-28)
      Objectives: The human oral microbiome, a complex ecosystem linked to oral and systemic health, harbors a diverse array of microbial populations, including antimicrobial resistance genes (ARGs). As a critical component of the One Health approach to tackle antibiotic resistance, comprehending the oral resistome's composition and diversity is imperative. The objective of this study was to ...
    • A solar cycle clock for extreme space weather 

      Chapman, Sandra; Dudok de Wit, de (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-08)
      The variable solar cycle of activity is a long-standing problem in physics. It modulates the overall level of space weather activity at earth, which in turn can have significant societal impact. The Hilbert transform of the sunspot number is used to map the variable length, approximately 11 year Schwabe cycle onto a uniform clock. The clock is used to correlate extreme space weather seen in the aa ...
    • General practitioners’ experiences of providing somatic care for patients with severe mental illness: a qualitative study 

      Jønsson, Alexandra Brandt Ryborg; Brodersen, John; Reventlow, Susanne; Svanholm, Christina; Møller, Anne; Kousgaard, Marius Brostrøm (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-22)
      Background Patients dealing with severe mental illnesses (SMI) often face suboptimal clinical outcomes and higher mortality rates due to a range of factors, including undetected physical health conditions. The provision of care for individuals with SMI is frequently disjointed, as they engage with diverse healthcare providers. Despite this fragmentation, primary care, particularly general practitioners ...
    • SLE: a cognitive step forward—a synthesis of rethinking theories, causality, and ignored DNA structures 

      Rekvig, Ole Petter (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-04)
      Systemic lupus erythematosus (SLE) is classified by instinctual classification criteria. A valid proclamation is that these formally accepted SLE classification criteria legitimate the syndrome as being difficult to explain and therefore enigmatic. SLE involves scientific problems linked to etiological factors and criteria. Our insufficient understanding of the clinical condition uniformly denoted ...
    • Proportion of venous thromboembolism attributed to recognized prothrombotic genotypes in men and women 

      Arnesen, Carl-Arne; Evensen, Line Holtet; Hveem, Kristian; Gabrielsen, Maiken Elvestad; Hansen, John Bjarne; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-08)
      Background: Data on the proportion of venous thromboembolism (VTE) risk attributed to prothrombotic genotypes in men and women are limited.<p> <p>Objectives: We aimed to estimate the population attributable fraction (PAF) of VTE for recognized, common prothrombotic genotypes in men and women using a populationbased case cohort. <p>Methods: Cases with incident VTE (n = 1493) and a randomly sampled ...
    • Deepfake detection using deep feature stacking and meta-learning 

      Naskar, Gourab; Mohiuddin, Sk; Malakar, Samir; Cuevas, Erik; Sarkar, Ram (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-15)
      Deepfake is a type of face manipulation technique using deep learning that allows for the replacement of faces in videos in a very realistic way. While this technology has many practical uses, if used maliciously, it can have a significant number of bad impacts on society, such as spreading fake news or cyberbullying. Therefore, the ability to detect deepfake has become a pressing need. This ...
    • The Impact of Climate Change on Construction Activity Performance 

      Oruc, Sertac; Dikbas, Huseyin Attila; Gumus, Berkin; Yucel, Ismail (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-31)
      There are specific construction operations that require weather forecast data to make short-term decisions regarding construction; however, most resource-related decision making and all project management plans must be carried out to anticipate weather conditions beyond the capabilities of the currently available forecasting technologies. In this study, a series of single- and multi-risk analyses ...
    • Digital Psychosocial Follow-up for Childhood Critical Illness Survivors: A Qualitative Interview Study on Health Professionals' Perspectives 

      Hagen, Marte Hoff; Hartvigsen, Gunnar; Jaccheri, Maria Letizia; Papavlasopoulou, Sofia (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-18)
      Background: Digital solutions have been reported to provide positive psychological and social outcomes to childhood critical illness survivors, a group with an increased risk for long-term adverse psychosocial effects. Objective: To explore health professionals’ perspectives on the potential of digital psychosocial follow-up for childhood critical illness survivors.<p> <p>Methods: Using a ...
    • Marine-Derived Peptides with Anti-Hypertensive Properties: Prospects for Pharmaceuticals, Supplements, and Functional Food 

      Walquist, Mari Johannessen; Eilertsen, Karl-Erik; Elvevoll, Edel Oddny; Jensen, Ida-Johanne (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-22)
      Hypertension, a major health concern linked to heart disease and premature mortality, has prompted a search for alternative treatments due to side effects of existing medications. Sustainable harvesting of low-trophic marine organisms not only enhances food security but also provides a variety of bioactive molecules, including peptides. Despite comprising only a fraction of active natural compounds, ...
    • Deep sequencing of Escherichia coli exposes colonisation diversity and impact of antibiotics in Punjab, Pakistan 

      Khawaja, Tamim; Mäklin, Tommi; Kallonen, Teemu; Gladstone, Rebecca Ashley; Pöntinen, Anna Kaarina; Mero, Sointu; Thorpe, Harry A.; Samuelsen, Ørjan; Parkhill, Julian; Izhar, Mateen; Akhtar, M. Waheed; Corander, Jukka; Kantele, Anu (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-18)
      Multi-drug resistant (MDR) E. coli constitute a major public health burden globally, reaching the highest prevalence in the global south yet frequently flowing with travellers to other regions. However, our comprehension of the entire genetic diversity of E. coli colonising local populations remains limited. We quantified this diversity, its associated antimicrobial resistance (AMR), and assessed ...
    • An Acupuncture Protocol for the Treatment of Erectile Dysfunction: A Delphi Process 

      Dahle, Merete Lindén; Alræk, Terje; Musial, Frauke (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-17)
      Introduction: Erectile dysfunction (ED) is a widespread disorder, and the worldwide incidence is rapidly increasing. Acupuncture, an intervention out of the spectrum of traditional Chinese medicine (TCM), has a long tradition as treatment for ED. Nonetheless, a best-practice treatment protocol is currently missing. A recent systematic review and meta-analysis confirmed a huge diversity of ...
    • Exploring the Potential of Atlantic Mesopelagic Species Processed on Board Commercial Fishing Vessels as a Source of Dietary Lipids 

      Alquiza Madina, Maria; Grimaldo Vela, Eduardo Enrique; Grimsmo, Leif; Toldnes, Bendik; Slizyte, Rasa; Carvajal, Ana Karina; Selnes, Merethe; Schei, Marte; Falch, Eva (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-02)
      This study investigates the use of untapped mesopelagic species as a source of long-chain polyunsaturated omega-3 fatty acids (LC n-3 PUFAs) to meet the growing demand. The challenges faced by commercial fishing vessels, such as varying catch rates and species distribution affecting lipid levels, are addressed. Marine oils were produced post-catch using thermal separation and enzymatic hydrolysis ...