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  • Should Clinicians Split or Lump Psychiatric Symptoms? The Structure of Psychopathology in Two Large Pediatric Clinical Samples from England and Norway 

    Fernández de la Cruz, Lorena; Vidal-Ribas, Pablo; Zahreddine, Nada; Mathiassen, Børge; Brøndbo, Per Håkan; Simonoff, Emily; Goodman, Robert; Stringaris, Argyris (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-14)
    It has been suggested that the structure of psychiatric phenomena can be reduced to a few symptom dimensions. These proposals, mainly based on epidemiological samples, may not apply to clinical populations. We tested the structure of psychiatric symptoms across two pediatric clinical samples from England (N=8434) and Norway (N=5866). Confirmatory factor analyses of the parent-reported Strengths ...
  • Discordance, Disclosure and Normative Gender Roles: Barriers to Couple Testing Within a Community-Level HIV Self-Testing Intervention in Urban Blantyre, Malawi 

    Kumwenda, Moses Kelly; Corbett, Elizabeth Lucy; Chikovore, Jeremiah; Phiri, Mackwellings; Mwale, Daniel; Choko, Augustine Talumba; Nliwasa, Marriot; Sambakunsi, Rodrick; Taegtmeyer, Miriam; Gutteberg, Tore Jarl; Munthali, Alister; Desmond, Nicola (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-06)
    A community-based HIV self-testing study in Blantyre, Malawi demonstrated that not all individuals living in couples tested with their partner. We describe factors dissuading individuals in couples from self-testing with their partner. Data were drawn from qualitative study exploring consequences of HIV self-testing within couples. In-depth interviews were conducted with 33 individuals living in ...
  • Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies 

    Wood, Angela M.; Kaptoge, Stephen; Butterworth, Adam S.; Willeit, Peter; Warnakula, Samantha; Bolton, Thomas; Paige, Ellie; Paul, Dirk S.; Sweeting, Michael; Burgess, Stephen; Bell, Steven; Astle, William; Stevens, David; Koulman, Albert; Selmer, Randi; Verschuren, W.M. Monique; Sato, Shinichi; Njølstad, Inger; Woodward, Mark; Salomaa, Veikko; Nordestgaard, Børge G.; Yeap, Bu B.; Fletcher, Astrid; Melander, Olle; Kuller, Lewis H.; Balkau, Beverley; Marmot, Michael; Koenig, Wolfgang; Casiglia, Edoardo; Cooper, Cyrus; Arndt, Volker; Franco, Oscar H.; Wennberg, Patrik; Gallacher, John; de la Cámara, Agustín Gómez; Völzke, Henry; Dahm, Christina C.; Dale, Caroline E.; Bergmann, Manuela M.; Crespo, Carlos J.; van der Schouw, Yvonne T.; Kaaks, Rudolf; Simons, Leon A.; Lagiou, Pagona; Schoufour, Josje D.; Boer, Jolanda M.A.; Key, Timothy J.; Rodriguez, Beatriz; Moreno-Iribas, Conchi; Davidson, Karina W.; Taylor, James O.; Sacerdote, Carlotta; Wallace, Robert B.; Quiros, J. Ramon; Tumino, Rosario; Blazer, Dan G.; Linneberg, Allan; Daimon, Makoto; Panico, Salvatore; Howard, Barbara; Skeie, Guri; Strandberg, Timo; Weiderpass, Elisabete; Nietert, Paul J.; Psaty, Bruce M.; Kromhout, Daan; Salamanca-Fernández, Elena; Kiechl, Stefan; Krumholz, Harlan M.; Grioni, Sara; Palli, Domenico; Huerta, Jose M.; Price, Jackie; Sundström, Johan; Arriola, Larraitz; Arima, Hisatomi; Travis, Ruth C.; Panagiotakos, Demosthenes B.; Karakatsani, Anna; Trichopoulou, Antonia; Kühn, Tilman; Grobbee, Diederick E.; Barrett-Connor, Elizabeth; van Schoor, Natasja; Boeing, Heiner; Overvad, Kim; Kauhanen, Jussi; Wareham, Nick; Langenberg, Claudia; Forouhi, Nita; Wennberg, Maria; Despres, Jean-Pierre; Cushman, Mary; Cooper, Jackie A.; Rodriguez, Carlos J.; Sakurai, Masaru; Shaw, Jonathan E.; Knuiman, Matthew; Voortman, Trudy; Meisinger, Christa; Tjønneland, Anne; Brenner, Hermann; Palmieri, Luigi; Dallongeville, Jean; Brunner, Eric J.; Assmann, Gerd; Trevisan, Maurizio; Gillum, Richard F.; Ford, Ian; Sattar, Naveed; Lazo, Mariana; Thompson, Simon G.; Ferrari, Pietro; Leon, David A.; Smith, George Davey; Peto, Richard; Jackson, Rod; Banks, Emily; Di Angelantonio, Emanuele; Danesh, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-12)
    <p><i>Background - </i>Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. <p><i>Methods - </i>We did a combined analysis of ...
  • Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK 

    Bhaskaran, Krishnan; dos-Santos-Silva, Isabel; Leon, David A.; Douglas, Ian J.; Smeeth, Liam (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-30)
    <i>Background</i>: BMI is known to be strongly associated with all-cause mortality, but few studies have been large enough to reliably examine associations between BMI and a comprehensive range of cause-specific mortality outcomes.<p> <p><i>Methods</i>: In this population-based cohort study, we used UK primary care data from the Clinical Practice Research Datalink (CPRD) linked to national ...
  • Agreement between preload reserve measured by impedance cardiography and echocardiography during pregnancy 

    Liang, Huan; Vårtun, Åse; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-05)
    <i>Purpose</i>: Accurate assessment of cardiac function is important during pregnancy. Echocardiography and impedance cardiography (ICG) are commonly used noninvasive methods to measure stroke volume (SV) and cardiac output (CO). The diference in stroke volume (ΔSV) or cardiac output (ΔCO) measured at baseline and after passive leg raising (PLR) is a measure of preload reserve that predicts volume ...
  • Soluble erythropoietin receptor levels associate with inflammatory mediators but not with disease activity or cumulative organ damage in patients with systemic lupus erythematosus 

    Jones, Heather; Raymond, Warren David; Eilertsen, Gro Østli; Nossent, Johannes (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-14)
    The erythropoietin receptor (EpoR) stimulates erythrocyte proliferation after erythropoietin binding. EpoR belongs to the cytokine receptor superfamily and can be found on macrophages and endothelial cells. As there are no data on the role of EpoR systemic autoimmune diseases, we investigated the role of soluble EpoR (sEpoR) in patients with systemic lupus erythematosus (SLE). In a cross-sectional ...
  • The treatment of PTSD in an older adult Norwegian woman using narrative exposure therapy: a case report 

    Mørkved, Nina; Thorp, Steven R. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-16)
    The bulk of the literature on effective treatments for posttraumatic stress disorder (PTSD) has focused on children, adolescents, and young adults. The evidence on treatments for older adults is sparse. This case report presents the application of narrative exposure therapy (NET) for a 70-year-old Norwegian woman suffering from PTSD as a result of multiple childhood and late life traumatic events. ...
  • The prevalence and possible risk factors of asthma in a subarctic child population. A study of asthma and allergy among schoolchildren i Nordland county 

    Hansen, Tonje Elisabeth (Doctoral thesis; Doktorgradsavhandling, 2019-05-07)
    Astmaepidemien de siste årtiene, har ført til at astma er blitt den vanligste kroniske sykdommen blant barn i den vestlige verden. Selv om studier fra ulike steder viser stor variasjon i forekomsten av astma, allergisk øye- og nesekatarr (rhinokonjunktivitt) og eksem, har man på tross av utstrakt forskning ikke funnet årsaken til sykdommene eller entydige forebyggende tiltak. Denne avhandlingen ...
  • Chinese herbal medicine Dengzhan Shengmai capsule as adjunctive treatment for ischemic stroke: A systematic review and meta-analysis of randomized clinical trials 

    Yang, Xiao-Ying; Wang, Li-Qiong; Li, Jin-Gen; Liang, Ning; Wang, Ying; Liu, Jian-Ping (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-09)
    <i>Objective</i>: The existing eligible randomized controlled trials (RCTs) were critically appraised for the effectiveness and safety of Chinese herbal medicine Dengzhan Shenmai for ischemic stroke.<p> <p><i>Design</i>: Systematic review and meta-analysis (CRD42016042914, http://www.crd.york.ac.uk/PROSPERO). Methods: Six electronic databases were searched from inception to May 2016. Risk ratio ...
  • Lifestyle factors including diet and biochemical biomarkers in acute intermittent porphyria: Results from a case-control study in northern Norway 

    Storjord, Elin; Dahl, Jim André; Landsem, Anne; Ludviksen, Judith K; Karlsen, Marlene; Karlsen, Bård Ove; Brekke, Ole-Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-10)
    <i>Background</i>: Lifestyle factors, including a low intake of carbohydrates, dieting, alcohol consumption, cigarette smoking and stress are some of the possible triggers of attacks in acute intermittent porphyria (AIP). The influence of lifestyle factors, including energy intake, diet and alcohol consumption on the biochemical disease activity in AIP and biochemical nutritional markers were ...
  • No overdiagnosis in the Norwegian Breast Cancer Screening Program estimated by combining record linkage and questionnaire information in the Norwegian Women and Cancer study 

    Lund, Eiliv; Nakamura, Aurelie; Thalabard, Jean-Christophe (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-12)
    <i>Background</i>: The Norwegian Breast Cancer Screening Program (NBCSP) was implemented across the country in 2005 and has been criticised for potential ‘overdiagnosis’, i.e. a breast cancer diagnosis that otherwise would not have been detected or treated in a woman’s lifetime. We aimed to estimate overdiagnosis in the NBCSP based on the Norwegian Women and Cancer (NOWAC) study using both ...
  • Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: towards a common nomenclature 

    Bender, Jennifer; Cattoir, Vincent; Hegstad, Kristin; Sadowy, Eva; Coque, Teresa M.; Westh, Henrik; Hammerum, Anette M.; Schaffer, Kirsten; Burns, Karen; Murchan, Stephen; Novais, Carla; Freitas, Ana R.; Peixe, Luísa; Del Grosso, Maria; Pantosti, Annalisa; Werner, Guido (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-02)
    Vancomycin-resistant enterococci (VRE) are important nosocomial pathogens. Invasive VRE infections are difficult to treat since common therapeutic options including ampicillin and glycopeptides often fail. In vitro, most VRE remain susceptible to last-resort antibiotics such as linezolid, tigecycline and daptomycin. However, neither tigecycline nor linezolid act in a bactericidal manner, and ...
  • Psychological distance of climate change and mental health risks assessment of smallholder farmers in Northern Ghana: Is habituation a threat to climate change? 

    Acharibasam, Jeremiah Wezanamo; Anuga, Samuel Weniga (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-06)
    Although strong evidence shows climate change has physical impacts on human health, the mental health impacts appear unclear. The study aims to understand and explain the dynamic correlates between climate change and farmers’ emotional regulation practices, given psychological distance. Using 180 smallholder farmers in Northern Ghana, structural equation linear regression analysis showed that ...
  • Reproducibility and repeatability of six high-throughput 16S rDNA sequencing protocols for microbiota profiling 

    Raju, Sajan C.; Lagström, Sonja; Ellonen, Pekka; de Vos, Willem M.; Eriksson, Johan Gunnar; Weiderpass, Elisabete; Rounge, Trine Ballestad (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-18)
    Culture-independent molecular techniques and advances in next generation sequencing (NGS) technologies make large-scale epidemiological studies on microbiota feasible. A challenge using NGS is to obtain high reproducibility and repeatability, which is mostly attained through robust amplification. We aimed to assess the reproducibility of saliva microbiota by comparing triplicate samples. The ...
  • Inhalant use in adolescents in northern Russia 

    Koposov, Roman A; Stickley, Andrew; Ruchkin, Vladislav (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-02)
    <i>Purpose</i>: To determine the prevalence of inhalant use in Russian adolescents and to investigate associated psychosocial problems from a gender perspective. <p> <p><i>Methods</i>: Data on inhalant use and comorbid psychopathology were collected by means of self-reports from 2892 (42.4% boys) sixth to tenth grade students in public schools in Arkhangelsk, Russia. Multivariate analysis of ...
  • Racial Variation in Echocardiographic Reference Ranges for Left Chamber Dimensions in Children and Adolescents: A Systematic Review 

    Majonga, Edith D.; Norrish, Gabrielle; Rehman, Andrea M.; Kranzer, Katharina; Mujuru, Hilda A.; Nathoo, Kusum; Odland, Jon Øyvind; Kaski, Juan P.; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-04)
    Abstract Echocardiography plays a critical role in the assessment of cardiac disease. Important differences in echocardiographically derived cardiac chamber dimensions have been previously highlighted in different population groups in adult studies, but this has not been systematically studied in children, whose body size changes throughout childhood. The aim of this study was to review the ...
  • Temperamental adaptability, persistence, and regularity: Parental ratings of Norwegian infants aged 6 to 12 months, with some implications for preventive practice 

    Olafsen, Kåre Sten; Ulvund, Stein Erik; Torgersen, Anne Mari; Wentzel-Larsen, Tore; Smith, Lars; Moe, Vibeke (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-24)
    There is a need for standardized measures of infant temperament to strengthen current practices in prevention and early intervention. The present study provides Norwegian data on the Cameron‐Rice Infant Temperament Questionnaire (CRITQ; J.R. Cameron & D.C. Rice, 1986a), which comprises 46 items and is used within a U.S. health maintenance organization. The CRITQ was filled out by mothers and fathers ...
  • Rethinking the carcinogenesis of breast cancer: The theory of breast cancer as a child deficiency disease or a pseudo semi-allograft 

    Lund, Eiliv; Busund, Lill-Tove Rasmussen; Thalabard, Jean-Christophe (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-23)
    The theory of breast cancer as a <i>child deficiency disease</i> is an <i>inversion of the current paradigm</i>, which considers fullterm pregnancies to be a protective factor and uses nulliparous women as the reference group. Instead, the theory of breast cancer as a child deficiency disease says that women with the highest parity (about 20, which is the limit of human fertility) are those with ...
  • Understanding Pain and Pain Management in Elderly Nursing Home Patients Applying an Interprofessional Learning Activity in Health Care Students: A Norwegian Pilot Study 

    Damsgård, Elin; Solgård, Hege; Johannessen, Karin; Wennevold, Katrine; Kvarstein, Gunnvald; Pettersen, Gunn; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-18)
    <p><i>Background - </i>Pain is common among elderly patients in nursing homes. However, pain assessment and treatment are inadequate. Interprofessional treatment is recommended, and consequently interprofessional education in pain management is necessary. <p><i>Aims - </i>This pilot project aimed to describe how two interprofessional groups of students approached pain management in two nursing ...
  • The Potential Usefulness of Virtual Reality Systems for Athletes: A Short SWOT Analysis 

    Düking, Peter; Holmberg, Hans-Christer; Sperlich, Billy (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-05)
    Virtual reality (VR) systems (Neumann et al., 2017), which are currently receiving considerable attention from athletes, create a two- or three-dimensional environment in the form of emulated pictures and/or video-recordings where in addition to being mentally present, the athlete even often feels like he/she is there physically as well. As she/he interacts with and/or reacts to this environment, ...

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