Recent additions

  • Biological stain collection – Absorbing paper is superior to cotton swabs 

    Janssen, Kirstin; Aune, Marthe; Olsen, Marita; Olsen, Gunn-Hege; Berg, Thomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-14)
    Biological evidence at crime scenes often contains very small amounts of DNA. Therefore, it is important to use the most effective sampling devices and procedures for stain collection. Currently, cotton swabs moistened with water are widely used, also in our laboratory. However, several studies have shown that other methods may be more efficient.<p> <p>In this study, we compared the DNA sampling ...
  • The retropubic tension-free vaginal tape procedure—Efficacy, risk factors for recurrence and long-term safety 

    Holdø, Bjørn; Verelst, Margareta; Svenningsen, Rune; Milsom, Ian; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-14)
    <i>Introduction</i> - The retropubic tension‐free vaginal tape has been the preferred method for primary surgical treatment of stress urinary incontinence and stress‐dominated mixed urinary incontinence in women for more than 20 years. This study presents long‐term safety and efficacy data and assesses risk factors for long‐term recurrence.<p> <p><i>Material and methods</i> - In a case‐series ...
  • Filtered beauty in Oslo and Tokyo: A spatial frequency analysis of facial attractiveness 

    Øvervoll, Morten; Schettino, Ilaria; Suzuki, Hikaru; Okubo, Matia; Laeng, Bruno (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-14)
    Images of European female and male faces were digitally processed to generate spatial frequency (SF) filtered images containing only a narrow band of visual information within the Fourier spectrum. The original unfiltered images and four SF filtered images (low, medium-low, medium-high and high) were then paired in trials that kept constant SF band and face gender and participants made a forced-choice ...
  • Responses to positive and aversive stimuli in estrous female rats housed in a seminatural environment: Effects of yohimbine and chlordiazepoxide 

    Le Moëne, Olivia; Ågmo, Anders j (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-05)
    The behavioral effects of putative anxiolytic and anxiogenic drugs are usually evaluated in highly standardized tests. Here, we determined the effects of such drugs in rats housed in mixed sex groups in a seminatural environment. Sexually receptive female Wistar rats were treated with either the anxiolytic drug chlordiazepoxide (2 mg/kg), the anxiogenic drug yohimbine (1 mg/kg), or saline (1 ml/kg). ...
  • Matrix metalloproteinase-9 mediated shedding of syndecan-4 in glomerular endothelial cells 

    Reine, Trine M.; Lanzalaco, Francesca; Kristiansen, Oddrun; Enget, Anne Randi; Satchell, Simon; Jenssen, Trond Geir; Kolset, Svein Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-31)
    <p><i>Background - </i>Diabetic nephropathy is the most common cause of end‐stage renal failure in the western world and Asia. The mechanisms are not fully elucidated, but disruption of glomerular endothelial glycocalyx and shedding of its components including syndecans has been implicated. <p><i>Aims - </i>We hypothesize that reduced glomerular filtration in diabetes is caused by disruption of ...
  • Dietary patterns of adults and their associations with Sami ethnicity, sociodemographic factors, and lifestyle factors in a rural multiethnic population of northern Norway - the SAMINOR 2 clinical survey 

    Petrenya, Natalia; Rylander, Charlotta; Brustad, Magritt (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-04)
    <i>Background</i> - Few population-based studies have assessed dietary behaviors in the rural multiethnic population of Northern Norway. The present study determined dietary patterns and investigated their association with Sami ethnicity, sociodemographic factors, and lifestyle factors in a multiethnic population in rural Northern Norway.<p> <p><i>Methods</i> - This cross-sectional study ...
  • Mucosal Metabolomic Profiling and Pathway Analysis Reveal the Metabolic Signature of Ulcerative Colitis 

    Diab, Joseph; Hansen, Terkel; Goll, Rasmus; Stenlund, Hans; Jensen, Einar; Moritz, Thomas; Florholmen, Jon; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-27)
    The onset of ulcerative colitis (UC) is characterized by a dysregulated mucosal immune response triggered by several genetic and environmental factors in the context of host–microbe interaction. This complexity makes UC ideal for metabolomic studies to unravel the disease pathobiology and to improve the patient stratification strategies. This study aims to explore the mucosal metabolomic profile in ...
  • MiRNAs‐181a/b therapy in lung cancer: reality or myth? 

    Braicu, Cornelia; Gulei, Diana; Cojocneanu, Roxana Maria; Raduly, Lajos; Jurj, Ancuta; Knutsen, Erik; Calin, George Adrian; Berindan-Neagoe, Ioana (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-03)
    Despite substantial progress in oncology, lung cancer remains the number one malignancy in terms of both incidence and mortality rates, and there thus remains an urgent need for new therapeutic alternatives. MicroRNA (miRNA) have an important role in cancer initiation and progression due to their capacity to interfere with transcriptional signaling and regulate key cellular processes. miR‐181a and ...
  • Use of skincare products and risk of cancer of the breast and endometrium: a prospective cohort study 

    Rylander, Charlotta; Veierød, Marit Bragelien; Weiderpass, Elisabete; Lund, Eiliv; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-03)
    <i>Background</i> - Concerns have been raised that extensive use of personal care products that contain endocrine disrupting compounds increase the risk of hormone sensitive cancers.<p> <p><i>Objective</i> - To assess the effect of skincare product use on the risk of pre- and postmenopausal breast cancer, estrogen receptor positive (ER+) and negative (ER-) breast cancer and cancer of the ...
  • Two interventions to treat pain disorders and post-traumatic symptoms among Syrian refugees: protocol for a randomized controlled trial 

    Hasha, Wegdan; Fadnes, Lars Thore; Igland, Jannicke; Vårdal, Rolf; Giusti, Line; Strømme, Elisabeth Marie; Haj Younes, Jasmin; Heltne, Unni Marie; Kumar, Bernadette Nirmal; Diaz, Esperanza (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-27)
    <i>Background</i> - There is a high prevalence of pain and post-traumatic symptoms among refugees and feasible interventions to manage these are needed. However, knowledge about the effect of physiotherapy and psychological group interventions among refugees is scarce. Our aim is to determine whether two different interventions, the Physiotherapy Activity and Awareness Intervention (PAAI) and ...
  • Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs 

    Pakstis, Andrew J.; Gurkan, Cemal; Dogan, Mustafa; Balkaya, Hasan Emin; Dogan, Serkan; Neophytou, Pavlos I.; Cherni, Lotfi; Boussetta, Sami; Khodjet-El-Khil, Houssein; ElGaaied, Amel Ben Ammar; Salvo, Nina Mjølsnes; Janssen, Kirstin; Olsen, Gunn-Hege; Hadi, Sibte; Almohammed, Eida Khalaf; Pereira, Vania; Truelsen, Ditte Mikkelsen; Bulbul, Ozlem; Soundararajan, Usha; Rajeevan, Haseena; Kidd, Judith R.; Kidd, Kenneth K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-08)
    The set of 55 ancestry informative SNPs (AISNPs) originally developed by the Kidd Lab has been studied on a large number of populations and continues to be applied to new population samples. The existing reference database of population samples allows the relationships of new population samples to be inferred on a global level. Analyses show that these autosomal markers constitute one of the better ...
  • Updating verbal fluency analysis for the 21st century: Applications for psychiatry 

    Holmlund, Terje Bektesevic; Cheng, Jian; Foltz, Peter W.; Cohen, Alex S.; Elvevåg, Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-07)
    Evaluating patients’ verbal fluency by counting the number of unique words (e.g., animals) produced in a short-period (e.g., 1–3 min) is one of the most widely employed cognitive tests in psychiatric research. We introduce new methods to analyze fluency output that leverage modern computational language technology. This enables moving beyond simple word counts to charting the temporal dynamics of ...
  • Nutrient-wide association study of 92 foods and nutrients and breast cancer risk 

    Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Papadimitriou, Nikos; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Fagherazzi, Guy; Boeing, Heiner; Ferrari, Pietro; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Kuhn, Tilman; Turzanski-Fortner, Renee; Schulze, Matthias B.; Karakatsani, Anna; Thriskos, Paschalis; Thrichopoulou, Antonia; Masala, Giovanna; Contiero, Paolo; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Bas; Bakker, Marije F.; van Gils, Carla H.; Olsen, Karina Standahl; Skeie, Guri; Lasheras, Cristina; Agudo, Antonio; Rodrigues-Barranco, Miguel; Sánchez, Maria-José; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Drake, Isabel; Ericson, Ulrika; Johansson, Ingegerd; Winkvist, Anna; Key, Tim; Freisling, Heinz; His, Mathilde; Huybrechts, Inge; Christakoudi, Sofia; Ellingjord-Dale, Merete; Riboli, Elio; Tsilidis, Konstantinos K.; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
    <i>Background</i> - Several dietary factors have been reported to be associated with risk of breast cancer, but to date, unequivocal evidence only exists for alcohol consumption. We sought to systematically assess the association between intake of 92 foods and nutrients and breast cancer risk using a nutrient-wide association study.<p> <p><i>Methods</i> - Using data from 272,098 women ...
  • A large-scale exome array analysis of venous thromboembolism 

    Lindström, Sara; Brody, Jennifer A.; Turman, Constance; Germain, Marine; Bartz, Traci M.; Smith, Erin N.; Chen, Ming-Huei; Puurunen, Marja; Chasman, Daniel; Hassler, Jeffrey; Pankratz, Nathan; Basu, Saonli; Guan, Weihua; György, Beata; Ibrahim, Manal; Empana, Jean-Philippe; Olaso, Robert; Jackson, Rebecca; Brækkan, Sigrid Kufaas; McKnight, Barbara; Deleuze, Jean-François; O'Donnell, Christopher J.; Jouven, Xavier; Frazer, Kelly A.; Psaty, Bruce M.; Wiggins, Kerri L.; Taylor, Kent; Reiner, Alexander P.; Heckbert, Susan R.; Kooperberg, Charles; Ridker, Paul; Hansen, John-Bjarne; Tang, Weihong; Johnson, Andrew D.; Morange, Pierre-Emmanuel; Trégouët, David A.; Kraft, Peter; Smith, Nicholas L.; Kabrhel, Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-19)
    Although recent Genome‐Wide Association Studies have identified novel associations for common variants, there has been no comprehensive exome‐wide search for low‐frequency variants that affect the risk of venous thromboembolism (VTE). We conducted a meta‐analysis of 11 studies comprising 8,332 cases and 16,087 controls of European ancestry and 382 cases and 1,476 controls of African American ancestry ...
  • Significance of progesterone receptors (PR-A and PR-B) expression as predictors for relapse after successful therapy of endometrial hyperplasia: a retrospective cohort study 

    Sletten, Elise Thoresen; Arnes, Marit; Lyså, Lena Marianne Myreng; Larsen, Marthe; Ørbo, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-25)
    <p><i>Objective - </i>After successful progestin therapy for endometrial hyperplasia (EH), the risk of relapse remains. We aimed to assess if immunohistochemical (IHC) expression of progesterone receptor isoforms, PR‐A and PR‐B, in endometrial glands and stroma in pre‐treatment endometrial biopsies was related to relapse of EH. <p><i>Design and setting - </i>Biopsy material originated from women ...
  • Nettside med virtuelt pasientrom forbereder studentene på praksis 

    Jensen, Catrine Buck; Huemer, Jeanette Elise; Furu, Rigmor; Iversen, Anita (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-17)
    Praksisportalen er en nettside som inneholder blant annet videoer, refleksjonsspørsmål og et virtuelt pasientrom. Sykepleierstudenter kan bruke Praksisportalen til å forberede seg til praksisstudiene. Nettsiden inneholder også informasjon for dem som skal veilede studentene når de er i praksis.
  • Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood 

    Brekke, Ole-Lars; Christiansen, Dorte; Kisserli, Aymric; Fure, Hilde; Dahl, Jim André; Donvito, Béatrice; Reveil, Brigitte; Ludviksen, Judith K; Tabary, Thierry; Mollnes, Tom Eirik; Cohen, Jacques H.M. (Journal article; Tidsskriftartikkel; Preprint; Manuskript, 2019-07-25)
    <i>Aim</i> - To study the role of complement receptor 1 (CR1) for binding of <i>Escherichia coli (E. coli)</i> to erythrocytes, for leukocyte phagocytosis, oxidative burst and complement activation in human whole blood from a CR1 deficient (CR1D) patient and healthy controls with low, medium and high CR1 numbers.<p> <p><i>Methods</i> - Alexa-labelled bacteria were used to quantify ...
  • Maternal cardiac function, uterine artery hemodynamics and natriuretic peptides at 22-24 weeks of gestation and subsequent development of hypertensive disorders of pregnancy 

    Liang, Huan; Vårtun, Åse; Flo, Kari; Widnes, Christian; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-26)
    <p><i>Introduction - </i>Maternal cardiac dysfunction as well as abnormal uterine artery (UtA) Doppler are associated with hypertensive disorders of pregnancy (HDP), but their relation is unclear. We investigated the correlation between maternal cardiac function, UtA hemodynamics and natriuretic peptides, and explored differences between women who subsequently developed HDP and those who did ...
  • Automated analysis of fetal cardiac function using color tissue Doppler imaging in second half of normal pregnancy 

    Herling, Lotta; Johnson, Jonas; Ferm-Widlund, Kjerstin; Bergholm, Fredrik; Elmstedt, Nina; Lindgren, Peter; Sonesson, Sven-Erik; Acharya, Ganesh; Westgren, Magnus (Journal article; Tidsskriftartikkel; Preprint; Manuskript, 2018-02-26)
    <i>Objectives</i> - Color tissue Doppler imaging (cTDI) is a promising tool for the assessment of fetal cardiac function. However, the analysis of myocardial velocity traces is cumbersome and time‐consuming, limiting its application in clinical practice. The aim of this study was to evaluate fetal cardiac function during the second half of pregnancy and to develop reference ranges using an ...
  • Design of galardine analogs as putative psudolysin inhibitors based on ab initio fragment molecular orbital calculations 

    Ezawa, Takuya; Sugiyama, Satoshi; Ara, Ayami; Sylte, Ingebrigt; Kurita, Noriyuki (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-29)
    Pseudolysin (PLN) is a metalloproteinase secreted from bacteria that degrades extracellular proteins to produce bacterial nutrition. It is thus expected that inhibitors against PLN can suppress the growth of bacteria and their pandemic spread. In addition, since these inhibitors do not attack to bacteria directly, there is a reduced risk for producing drug-resistant bacteria. On the other hand, as ...

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