Recent additions

  • Amnioexchange for gastroschisis does not help, and may even harm 

    Bhide, Amarnath (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-24)
    This is a mini commentary on D Luton et al., pp. 1233–1241 in this issue. To view this article visit https://doi.org/10.1111/1471-0528.15804.
  • Initiation of systemic therapy during the last 30 days of life in patients with metastatic castration-resistant prostate cancer 

    Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård; Pawinski, Adam; Yobuta, Rosalba; Norum, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
    <b>Background/Aim</b>: Compared to intravenous taxane chemotherapy, newer orally-available and/or less toxic agents for metastatic castration-resistant prostate cancer (MCRPC) may be associated with higher likelihood of starting treatment in patients with adverse prognostic features and limited life expectancy. To test this hypothesis, we analyzed the rates of treatment initiation during the last ...
  • Fetal and neonatal alloimmune thrombocytopenia - The Norwegian management model 

    Tiller, Heidi; Ahlen, Maria Therese; Akkøk, Cigdem Ahaein; Husebekk, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-31)
    In Norway, the management strategy for fetal and neonatal alloimmune thrombocytopenia (FNAIT) has for more than two decades differed from most other countries. The focus of this paper is to describe and discuss the Norwegian FNAIT management program. We recommend antenatal IVIg to women who previously have had a child with FNAIT-induced ICH, and usually not to HPA-1a alloimmunized pregnant women ...
  • Measuring the effects of sharing mHealth data during diabetes consultations: a mixed-method study protocol 

    Bradway, Meghan; Giordanengo, Alain; Joakimsen, Ragnar Martin; Hansen, Anne Helen; Grøttland, Astrid; Hartvigsen, Gunnar; Randine, Pietro; Årsand, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-10)
    <i>Background</i>: There is rising demand for health care’s limited resources. Mobile health (mHealth) could be a solution, especially for those with chronic illnesses such as diabetes. mHealth can increases patients’ options to self-manage their health, improving their health knowledge, engagement, and capacity to contribute to their own care decisions. However, there are few solutions for sharing ...
  • Psychiatric Risk Assessment from the Clinician´s Perspective: Lessons for the Future 

    Cohen, Alex S.; Fedechko, Taylor L.; Schwartz, Elana K.; Le, Thanh P.; Foltz, Peter W.; Bernstein, Jared; Cheng, Jian; Rosenfeld, Elizabeth; Elvevåg, Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-01)
    Accurate prediction of risk-states in Serious Mental Illnesses (SMIs) is critical for reducing their massive societal burden. Risk-state assessments are notably inaccurate. Recent innovations, including widely available and inexpensive mobile technologies for ambulatory “biobehavioral” data, can reshape risk assessment. To help understand and accelerate clinician involvement, we surveyed 90 ...
  • Murine models for studying treatment, prevention and pathogenesis of FNAIT 

    Rasmussen, Trude Victoria; Ahlen, Maria Therese (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-31)
    Maternal alloimmunization to paternally inherited antigens on fetal/neonatal platelets can cause fetal/neonatal alloimmune thrombocytopenia (FNAIT) after antibody-mediated removal of platelets from the fetal circulation. The complications vary from mild bleeding symptoms to severe intracranial hemorrhage and subsequent neurological impairment or death. Studies on <i>in vivo</i> mechanisms are ...
  • Second re-irradiation: A delicate balance between safety and efficacy 

    Nieder, Carsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-08)
    Except for straightforward palliative indications such as painful bone metastases, re-irradiation is often characterized by a narrow therapeutic window and the potential for decreased efficacy and increased toxicity, especially if the cumulative total dose from both courses is high. Second re-irradiations tend to pose even bigger challenges and are thus offered in a restrictive manner to highly ...
  • C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations 

    Butler, Christopher C; Gillespie, David; White, Patrick; Bates, Janine; lowe, rachel; Thomas-Jones, Emma; Wootton, Mandy; Hood, Kerenza; Phillips, Rhiannon; Melbye, Hasse; Llor, Carl; Cals, Jochen W L; Naik, Gurudutt; Kirby, Nigel; Gal, Micaela; Riga, Evgenia; Francis, Nick A (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-11)
    <i>BACKGROUND</i> - Point-of-care testing of C-reactive protein (CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD).<p><p> <i>METHODS</i> - We performed a multicenter, open-label, randomized, controlled trial involving patients with a diagnosis of COPD in their primary care clinical ...
  • Simuleringsbasert teamtrening virker 

    Brattebø, Guttorm; Ersdal, Hege Langli; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-09)
    Trening av tverrprofesjonelle team med bruk av simulering brukes særlig ved forberedelse til akuttmedisinske situasjoner. Det foreligger nå god dokumentasjon for at slik trening har betydning for pasientene. 27. mars 1977 skjedde verdens hittil verste flykatastrofe, der 583 personer omkom på Tenerife etter at to jumbojeter kolliderte på flyplassen i tett tåke. Granskningen etter katastrofen ...
  • Hospitalization as a trigger for venous thromboembolism – Results from a population-based case-crossover study 

    Bjøri, Esben; Johnsen, Håkon Sandbukt; Hansen, John-Bjarne; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-21)
    <i>Background</i> - Previous studies have reported that around 50% of patients with venous thromboembolism (VTE) has undergone recent hospitalization. However, studies on the impact of hospitalization as a trigger factor for VTE are limited.<p><p> <i>Objectives</i> - To investigate the impact of hospitalization with and without concurrent immobilization as a trigger factor for VTE.<p><p> ...
  • Efficacy of mecillinam against clinical multidrug-resistant Escherichia coli in a murine urinary tract infection model 

    Zykov, Ilya Nikolaevich; Frimodt-Møller, Niels; Småbrekke, Lars; Sundsfjord, Arnfinn; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-23)
    Pivmecillinam, a pro-drug of mecillinam, has been used extensively in Scandinavia for the treatment of acute lower urinary tract infections (UTIs) caused by Enterobacterales. It is still an attractive first-line drug for the empirical treatment of UTIs owing to the low prevalence of resistance as well as its favourable impact on the intestinal microbiota as a pro-drug and good in vitro efficacy ...
  • Impact of Osteoporotic Fracture Type and Subsequent Fracture on Mortality: The Tromsø Study 

    Alarkawi, Dunia; Bluic, Dana; Tran, T; Ahmed, Luai A; Emaus, Nina; Bjørnerem, Åshild; Jørgensen, Lone; Cristoffersen, T.; Eisman, JA; Center, JR (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-26)
    <i>Summary</i> - Less is known about the impact of non-hip non-vertebral fractures (NHNV) on early death. This study demonstrated increased risk of dying following hip and NHNV fractures which was further increased by a subsequent fracture. This highlights the importance of early intervention to prevent both initial and subsequent fractures and improve survival.<p> <p><i>Introduction</i> - ...
  • Microbial risk factors for treatment failure of pivmecillinam in community‐acquired urinary tract infections caused by ESBL‐producing Escherichia coli 

    Syre, Heidi; Hetland, Marit; Bernhoff, Eva; Bollestad, Marianne; Grude, Nils; Simonsen, Gunnar Skov; Löhr, Iren Høyland (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-22)
    The aim of this study was to identify microbial risk factors for treatment failure of pivmecillinam in community‐acquired urinary tract infections (ca‐UTIs) caused by ESBL‐producing Escherichia coli. Eighty‐nine ESBL‐producing E. coli isolated from women suffering from ca‐UTIs were included. The susceptibilities to mecillinam were determined using MIC gradient strip. Whole genome sequencing was ...
  • Exploring the pangenome of Staphylococcus haemolyticus. Colonisation, hospital adaption, pathogenicity and novel species identification 

    Pain, Maria Charlene Ronessen (Doctoral thesis; Doktorgradsavhandling, 2020-04-03)
    Staphylococcus haemolyticus is a ubiquitous bacterium recognised as a significant cause of nosocomial infections. Today it represents one of the most clinically relevant staphylococcal species, hallmarked by its extreme genome plasticity and multiresistant phenotype. Despite its relevance, little is known about its virulence repertoire or how it causes disease. The main objective of this PhD thesis ...
  • Inflammatory serum markers and risk and severity of prostate cancer: The PROCA‐life study 

    Stikbakke, Einar; Richardsen, Elin; Knutsen, Tore; Wilsgaard, Tom; Giovannucci, Edward L; McTiernan, Anne; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-03)
    Whether chronic inflammation mirrored by high levels of systemic inflammatory markers such as high sensitive‐CRP (hs‐CRP) and white blood cell count (WBC) are associated with prostate cancer development remains unclear. In the Prostate Cancer Study throughout Life (PROCA‐<i>life</i>), a prospective population‐based cohort study, 7,356 men were included. Prediagnostic WBC and hs‐CRP were assessed ...
  • Altered mitochondrial metabolism in the insulin-resistant heart 

    Makrecka-Kuka, Marina; Liepinsh, Edgars; Murray, Andrew J.; Lemieux, Hélène; Dambrova, Maija; Tepp, Kersti; Puurand, Marju; Käämbre, Tuuli; Han, Woo H.; de Goede, Paul; O'Brien, Katie A.; Turan, Belma; Tuncay, Erkan; Olgar, Yusuf; Rolo, Anabela P.; Palmeira, Carlos M.; Boardman, Neoma Tove; Wüst, Rob C.I.; Larsen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-16)
    Obesity‐induced insulin resistance and type 2 diabetes mellitus can ultimately result in various complications, including diabetic cardiomyopathy. In this case, cardiac dysfunction is characterized by metabolic disturbances such as impaired glucose oxidation and an increased reliance on fatty acid (FA) oxidation. Mitochondrial dysfunction has often been associated with the altered metabolic function ...
  • An integrative review on the information and communication needs of parents of children with cancer regarding the use of complementary and alternative medicine 

    Stub, Trine; Kristoffersen, Agnete Egilsdatter; Overvåg, Grete; Jong, Miek C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-17)
    <i>Background</i> - Parents often choose Complementary and Alternative Medicine (CAM) as a supportive agent with the aim to reduce cancer treatment-related symptoms in their children. Therefore, it is necessary to understand parents´ information and communication needs regarding CAM. The aim of the present study was to review the research literature as to identify the information and communication ...
  • Sex differences in placental circulation 

    Widnes, Christian (Doctoral thesis; Doktorgradsavhandling, 2020-04-03)
    Sexual dimorphism in placental morphology and function has increasingly been acknowledged. The differences in adaptation to the intrauterine environment and in perinatal/neonatal outcomes between the sexes has been well described. Doppler-derived hemodynamic parameters of the feto-placental and utero-placental circulations are commonly used to monitor fetal wellbeing in clinical practice, but whether ...
  • Qualitative analysis of European and Middle East intensive care unit nursing death rituals 

    Benbenishty, Julie; Bennun, Maureen; Lind, Ranveig (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-22)
    <b>Background:</b><br> Grieving and death rituals vary widely across cultures and are often influenced by geographical regions, religions, and local norms. Nursing rituals reflect the forms of cultural behaviour that assist in communicating traditional knowledge and practices. They help nurses maintain social order through cohesion and interaction. <br><b>Aim and objectives:</b> Exploration of ...
  • Agreement between anatomical M-mode and tissue Doppler imaging in the assessment of fetal atrioventricular annular plane displacement in uncomplicated pregnancies: A prospective longitudinal study 

    Zanardini, Cristina; D'Antonio, Francesco; Hvingel, Bodil; Vårtun, Åse; Prefumo, Federico; Flacco, Maria E.; Manzoli, Lamberto; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-23)
    Aim To evaluate the level of agreement between M‐mode and pulsed‐wave tissue Doppler imaging (PW‐TDI) techniques in assessing fetal mitral annular plane systolic excursion (MAPSE), tricuspid annular plane systolic excursion (TAPSE) and septal annular plane systolic excursion (SAPSE) in a low‐risk population. Methods This prospective longitudinal study included healthy fetuses assessed from 18 to ...

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