Recent additions

  • Impact of Osteoporotic Fracture Type and Subsequent Fracture on Mortality: The Tromsø Study 

    Alarkawi, Dunia; Bluic, Dana; Tran, T; Ahmed, Luai A; Emaus, Nina; Bjørnerem, Åshild; Jørgensen, Lone; Cristoffersen, T.; Eisman, JA; Center, JR (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-26)
    <i>Summary</i> - Less is known about the impact of non-hip non-vertebral fractures (NHNV) on early death. This study demonstrated increased risk of dying following hip and NHNV fractures which was further increased by a subsequent fracture. This highlights the importance of early intervention to prevent both initial and subsequent fractures and improve survival.<p> <p><i>Introduction</i> - ...
  • Microbial risk factors for treatment failure of pivmecillinam in community‐acquired urinary tract infections caused by ESBL‐producing Escherichia coli 

    Syre, Heidi; Hetland, Marit; Bernhoff, Eva; Bollestad, Marianne; Grude, Nils; Simonsen, Gunnar Skov; Löhr, Iren Høyland (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-22)
    The aim of this study was to identify microbial risk factors for treatment failure of pivmecillinam in community‐acquired urinary tract infections (ca‐UTIs) caused by ESBL‐producing Escherichia coli. Eighty‐nine ESBL‐producing E. coli isolated from women suffering from ca‐UTIs were included. The susceptibilities to mecillinam were determined using MIC gradient strip. Whole genome sequencing was ...
  • Exploring the pangenome of Staphylococcus haemolyticus. Colonisation, hospital adaption, pathogenicity and novel species identification 

    Pain, Maria Charlene Ronessen (Doctoral thesis; Doktorgradsavhandling, 2020-04-03)
    Staphylococcus haemolyticus is a ubiquitous bacterium recognised as a significant cause of nosocomial infections. Today it represents one of the most clinically relevant staphylococcal species, hallmarked by its extreme genome plasticity and multiresistant phenotype. Despite its relevance, little is known about its virulence repertoire or how it causes disease. The main objective of this PhD thesis ...
  • Inflammatory serum markers and risk and severity of prostate cancer: The PROCA‐life study 

    Stikbakke, Einar; Richardsen, Elin; Knutsen, Tore; Wilsgaard, Tom; Giovannucci, Edward L; McTiernan, Anne; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-03)
    Whether chronic inflammation mirrored by high levels of systemic inflammatory markers such as high sensitive‐CRP (hs‐CRP) and white blood cell count (WBC) are associated with prostate cancer development remains unclear. In the Prostate Cancer Study throughout Life (PROCA‐<i>life</i>), a prospective population‐based cohort study, 7,356 men were included. Prediagnostic WBC and hs‐CRP were assessed ...
  • Altered mitochondrial metabolism in the insulin-resistant heart 

    Makrecka-Kuka, Marina; Liepinsh, Edgars; Murray, Andrew J.; Lemieux, Hélène; Dambrova, Maija; Tepp, Kersti; Puurand, Marju; Käämbre, Tuuli; Han, Woo H.; de Goede, Paul; O'Brien, Katie A.; Turan, Belma; Tuncay, Erkan; Olgar, Yusuf; Rolo, Anabela P.; Palmeira, Carlos M.; Boardman, Neoma Tove; Wüst, Rob C.I.; Larsen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-16)
    Obesity‐induced insulin resistance and type 2 diabetes mellitus can ultimately result in various complications, including diabetic cardiomyopathy. In this case, cardiac dysfunction is characterized by metabolic disturbances such as impaired glucose oxidation and an increased reliance on fatty acid (FA) oxidation. Mitochondrial dysfunction has often been associated with the altered metabolic function ...
  • An integrative review on the information and communication needs of parents of children with cancer regarding the use of complementary and alternative medicine 

    Stub, Trine; Kristoffersen, Agnete Egilsdatter; Overvåg, Grete; Jong, Miek C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-17)
    <i>Background</i> - Parents often choose Complementary and Alternative Medicine (CAM) as a supportive agent with the aim to reduce cancer treatment-related symptoms in their children. Therefore, it is necessary to understand parents´ information and communication needs regarding CAM. The aim of the present study was to review the research literature as to identify the information and communication ...
  • Sex differences in placental circulation 

    Widnes, Christian (Doctoral thesis; Doktorgradsavhandling, 2020-04-03)
    Sexual dimorphism in placental morphology and function has increasingly been acknowledged. The differences in adaptation to the intrauterine environment and in perinatal/neonatal outcomes between the sexes has been well described. Doppler-derived hemodynamic parameters of the feto-placental and utero-placental circulations are commonly used to monitor fetal wellbeing in clinical practice, but whether ...
  • Qualitative analysis of European and Middle East intensive care unit nursing death rituals 

    Benbenishty, Julie; Bennun, Maureen; Lind, Ranveig (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-22)
    <b>Background:</b><br> Grieving and death rituals vary widely across cultures and are often influenced by geographical regions, religions, and local norms. Nursing rituals reflect the forms of cultural behaviour that assist in communicating traditional knowledge and practices. They help nurses maintain social order through cohesion and interaction. <br><b>Aim and objectives:</b> Exploration of ...
  • Agreement between anatomical M-mode and tissue Doppler imaging in the assessment of fetal atrioventricular annular plane displacement in uncomplicated pregnancies: A prospective longitudinal study 

    Zanardini, Cristina; D'Antonio, Francesco; Hvingel, Bodil; Vårtun, Åse; Prefumo, Federico; Flacco, Maria E.; Manzoli, Lamberto; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-23)
    Aim To evaluate the level of agreement between M‐mode and pulsed‐wave tissue Doppler imaging (PW‐TDI) techniques in assessing fetal mitral annular plane systolic excursion (MAPSE), tricuspid annular plane systolic excursion (TAPSE) and septal annular plane systolic excursion (SAPSE) in a low‐risk population. Methods This prospective longitudinal study included healthy fetuses assessed from 18 to ...
  • Quantifying the impact of treatment history on plasmid-mediated resistance evolution in human gut microbiota 

    Tepekule, Burcu; Abel zur Wiesch, Pia; Kouyos, Roger D.; Bonhoeffer, Sebastian (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-30)
    To understand how antibiotic use affects the risk of a resistant infection, we present a computational model of the population dynamics of gut microbiota including antibiotic resistance-conferring plasmids. We then describe how this model is parameterized based on published microbiota data. Finally, we investigate how treatment history affects the prevalence of resistance among opportunistic ...
  • Antibiotic prescribing for acute Respiratory tract infections 12 months after communication and CRP training: a randomized trial 

    Little, Paul; Stuart, Beth; Francis, Nick A; Douglas, Elaine; Tonkin-Crine, Sarah; Anthierens, Sibyl; Cals, Jochen W L; Melbye, Hasse; Santer, Miriam; Moore, Michael; Coenen, Samuel; Butler, Christoffer C; Hood, Kerenza; Kelson, Mark; Godycki-Cwirko, Maciek; Mierzecki, Artur; Torres, Antoni; Llor, Carl; Davies, Melanie; Mullee, Mark; O'Reilly, Gilly; van der Velden, Alike; Geraghty, Adam; Goossens, Herman; Verheij, Theo; Yardley, Lucy (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03)
    <i>PURPOSE</i> - C-reactive-protein (CRP) is useful for diagnosis of lower respiratory tract infections (RTIs). A large international trial documented that Internet-based training in CRP point-of-care testing, in enhanced communication skills, or both reduced antibiotic prescribing at 3 months, with risk ratios (RRs) of 0.68, 0.53, 0.38, respectively. We report the longer-term impact in this ...
  • MCPyV Large T antigen induced atonal homolog 1 (ATOH1) is a lineage-dependency oncogene in Merkel cell carcinoma. 

    Fan, Kaiji; Gravemeyer, Jan; Ritter, Cathrin; Rasheed, Kashif; Gambichler, Thilo; Moens, Ugo Lionel; Shuda, Masahiro; Schrama, David; Becker, Jürgen C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-07)
    Despite the fact that the transcription factor ATOH1 is a master regulator of Merkel cell development, its role in Merkel cell carcinoma (MCC) carcinogenesis remains controversial. Here, we provide several lines of evidence that ATOH1 is a lineage-dependent oncogene in MCC. Luciferase assays revealed binding of ATOH1 and subsequent activation to the promoter of miR-375, which is one of the most ...
  • Nære relationers indvirkning på livsmodet 

    Delmar, Charlotte (Tidsskriftartikkel; Peer reviewed, 2019-11-08)
    The purpose of this essay is to describe how close relations have impact on sick person’s life courage. Life courage is an existential life phenomenon. The life phenomena life courage and joy of life are in this article the key phenomena to be focused on. The article describes both differences and similarities between relational-ethical and existential life phenomena, which can promote but also ...
  • Døden- en del av livet 

    Nymo, Randi Inger Johanne (Tidsskriftartikkel; Peer reviewed, 2019)
    Artikkelen handler om døden som en del av livet. Forfatteren bruker fortelling fra eget liv som same ien markebygd iNord-Norge for ågi en forståelse av hvordan pleie og omsorg ved livets slutt kan ta form. Det er familiebasert omsorg hvor hele familien deltar, også barn og unge. Slekt og naboer er med. Døden og livet blir forenet ien kulturell tradisjon. Sykepleier fra Norges ...
  • Dynamic balance and gait speed improve in persons with Parkinson's disease after Lee Silverman Voice Treatment (LSVT)-BIG training: a single subject experimental design study 

    Kleppang, Tale Tangen; Jørgensen, Lone (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-30)
    <i>Background</i>: Parkinson ́s disease (PD) is characterised by small, slow movements affecting balance and gait. Lee-Silverman-Voice-Treatment-(LSVT)-BIG is an intensive intervention aiming to restore normal amplitudes of movements. This study aimed to examine whether LSVT-BIG influences dynamic balance and gait in persons with PD.<p> <p><i>Methods</i>: We used a Single-Subject-Experimental-Design ...
  • Coronary heart disease and cardiac rehabilitation. Participation rate, predictors and effects on symptoms of anxiety and depression, and employment status of patients following percutaneous coronary intervention - A nationwide prospective cohort study 

    Olsen, Siv Jorunn Storli (Doctoral thesis; Doktorgradsavhandling, 2020-04-03)
    The aims of this thesis were to study CR participation rate, clinically relevant anxiety and depression and employment status of patients following percutaneous coronary intervention (PCI), and the long-term effect of participation in a CR programme on patients’ symptoms of anxiety and depression and their employment status. Using a prospective observational design, we included data from the Norwegian ...
  • A longitudinal investigation of immigrant children’s ethnic and national identities 

    Froehlich, Laura; Martiny, Sarah E.; Deaux, Kay (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-22)
    How immigrants define their ethnicity and nationality is relevant for integration: They can identify with their ethnic group, the receiving society, and a combination of both. A longitudinal study with elementary-school children with migration background (N = 200; age 9-10) in Germany investigated the predictors and stability of ethnic and national identity. Ethnic identity was more highly endorsed ...
  • Genetic Variation Of Platelet Glycoprotein VI And The Risk Of Venous Thromboembolism 

    Skille, Hanne; Paulsen, Benedikte; Hveem, Kristian; Gabrielsen, Maiken Elvestad; Brumpton, Ben Michael; Hindberg, Kristian; Gran, Olga Vikhammer; Rosendaal, Frits Richard; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-07)
    Family studies have indicated that heritability explains 50-60% of the venous thromboembolism (VTE) events, and in recent years, several single nucleotide polymorphisms (SNPs) have been found to influence the VTE risk. Glycoprotein 6 (GP6) rs1613662, also known as T13254C, is an A/G single nucleotide variation in amino acid 219, which results in a serine to proline substitution affecting ...
  • Palliative patients get greater relief from early screening of symptoms and implementation of measures 

    Vigstad, Sverre; Clancy, Anne; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-21)
    <i>Background</i>: Palliative cancer patients experience a complex clinical picture. Research shows little correlation between nurses’ impressions of the patient’s symptoms and the patient’s experience of their own symptoms. National guidelines recommend the use of screening tools to chart and evaluate the patient’s symptoms systematically.<p><p> <i>Objective</i>: The objective of the study is ...
  • Brukermedvirkning, likeverd og forutsigbarhet for den eldre pasienten 

    Evju, Anne Svelstad (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
    Den nylig utgitte Nasjonal helse- og sykehusplan 2020-2023 (Meld. St. 7 (2019-2020)) gir retning og rammer for utvikling av spesialisthelsetjenesten og samarbeidet med den kommunale helse- og omsorgstjenesten de neste fire årene. Brukermedvirkning, likeverdighet og forutsigbarhet er viktige prinsipper som fremheves i planen og som vi som helsepersonell skal strebe etter å innfri. Hvordan kan vi ...

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