Recent additions

  • A Probabilistic Bag-to-Class Approach to Multiple-Instance Learning 

    Møllersen, Kajsa; Hardeberg, Jon Yngve; Godtliebsen, Fred (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)
    Multi-instance (MI) learning is a branch of machine learning, where each object (bag) consists of multiple feature vectors (instances)—for example, an image consisting of multiple patches and their corresponding feature vectors. In MI classification, each bag in the training set has a class label, but the instances are unlabeled. The instances are most commonly regarded as a set of points in a ...
  • The Northern Norway mother-and-child contaminant cohort study: implementation, population characteristics and summary of dietary findings 

    Veyhe, Anna Sofia; Hansen, Solrunn; Sandanger, Torkjel Manning; Nieboer, Evert; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-28)
    <p><i>Objectives.</i> To describe the essential features of a new Northern Norway mother-and-child contaminant cohort study called MISA, including its rationale, content, implementation and selected findings (mostly dietary). <p><i>Study design. </i>Cross-sectional with longitudinal aspects. <p><i>Methods.</i> Five hundred and fifteen eligible women were enrolled in early pregnancy, with 391 ...
  • Endothelial function after pancreas transplantation - A single-center observational study 

    Nordheim, Espen; Dahle, Dag Olav; Strøm Halden, Thea Anine; Birkeland, Kåre I.; Åsberg, Anders; Hartmann, Anders; Horneland, Rune; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)
    <i>Background</i> - Patients with diabetes mellitus treated with successful pancreas transplantation (PTX) normalize hyperglycemia, but are exposed to immunosuppressive drugs that may impair endothelial function. This study aimed to evaluate endothelial function in single PTX recipients.<p><p> <i>Methods</i> - Flow‐mediated dilatation (FMD) in the brachial artery was measured by ultrasound 8 weeks ...
  • Intestinal fungi are causally implicated in microbiome assembly and immune development in mice 

    van Tilburg Bernardes, Erik; Pettersen, Veronika Kucharova; W. Gutierrez, Mackenzie; Isabelle, Laforest-Lapointe; Marie-Claire, Arrieta (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-22)
    The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fungi, or both to differentiate the causal role of fungi on microbiome assembly, immune development, ...
  • The art of yoik in care: Sami caregivers' experiences in dementia in Northern Norway 

    Hämäläinen, Soile; Musial, Frauke; Graff, Ola; Schirmer, Henrik; Salamonsen, Anita; Mehus, Grete (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)
    <i>Purpose</i>: Yoik is the traditional vocal art of the Sami, the indigenous people of Fennoscandia. The Sami people, their land and their culture have been subject to colonisation and assimilation for centuries, hence the practice of yoik was lost in many regions. Despite an increasing awareness of the benefits of health musicking, yoik is only sporadically included in musicking practices in ...
  • The Vaginal-PVPA: A Vaginal Mucosa-Mimicking In Vitro Permeation Tool for Evaluation of Mucoadhesive Formulations 

    Falavigna, Margherita; Pattacini, Martina; Wibel, Richard; Sonvico, Fabio; Skalko-Basnet, Natasa; Flaten, Gøril Eide (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-19)
    Drug administration to the vaginal site has gained increasing attention in past decades, highlighting the need for reliable in vitro methods to assess the performance of novel formulations. To optimize formulations destined for the vaginal site, it is important to evaluate the drug retention within the vagina as well as its permeation across the mucosa, particularly in the presence of vaginal fluids. ...
  • The record-warm Barents Sea and 0-group fish response to abnormal conditions 

    Eriksen, Elena; Bagøien, Espen; Strand, Espen; Primicerio, Raul; Prokhorova, Tatiana; Trofimov, Alexander; Prokopchuk, Irina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-25)
    The Barents Sea is a nursery area for many commercially and ecologically important fish stocks, and this whole region is presently subject to rapid climatic change from a cold period in the 1980s to a record warm period in the latest decade, with a peak in 2016. The present study focuses exclusively on year 2016, which was characterized by record warm air and seawater and an exceptionally large ...
  • Host dependent maintenance of a blaNDM-1-encoding plasmid in clinical Escherichia coli isolates 

    Alves Gama, Joao Pedro; Kloos, Julia Maria; Johnsen, Pål Jarle; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-09)
    Dissemination of bacterial clones carrying plasmid-mediated resistance genes is a major factor contributing to the increasing prevalence of antibiotic resistance. Understanding the evolution of successful clones and the association to mobile resistance elements are therefore crucial. In this study, we determined the sequence of a 145 kb IncC multi-drug resistance plasmid (pK71-77-1-NDM), harbouring ...
  • Physical Activity With Tailored mHealth Support for Individuals With Intellectual Disabilities: Study Protocol for a Randomized Controlled Trial 

    Michalsen, Henriette; Wangberg, Silje C; Hartvigsen, Gunnar; Jaccheri, Maria Letizia; Muzny, Miroslav; Henriksen, André; Olsen, Monica Isabel Benedikte; Thrane, Gyrd; Jahnsen, Reidun Birgitta; Pettersen, Gunn; Arntzen, Cathrine; Anke, Audny (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-29)
    <i>Background</i>: Individuals with intellectual disabilities (IDs) have lower levels of physical activity (PA) and greater barriers for participation in fitness activities compared with members of the general population. As increased PA has positive effects on cardiovascular and psychosocial health, it is exceedingly important to identify effective interventions for use in everyday settings. Mobile ...
  • Adult attachment style and maternal-infant bonding: the indirect path of parenting stress 

    Nordahl, Dag; Rognmo, Kamilla; Bohne, Agnes; Landsem, Inger Pauline; Moe, Vibeke; Wang, Catharina Elisabeth Arfwedson; Høifødt, Ragnhild Sørensen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-08)
    <i>Background</i> - The quality of maternal-infant bonding is related to important child outcomes. The literature has assumed that the ability to form relationships is a relatively stable trait, and research studies have suggested that a mother’s attachment style in close adult relationships is related to mother-infant bonding. The transition to parenthood is also often stressful, and the adult ...
  • Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016 

    Fullman, Nancy; Barber, Ryan M.; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abdulle, Abdishakur M.; Abera, Semaw Ferede; Aboyans, Victor; Abu-Raddad, Laith J.; Abu-Rmeileh, Niveen M. E.; Aryal, Krishna Kumar; Htet, Aung Soe; Kisa, Adnan; Norheim, Ole Frithjof; Vollset, Stein Emil; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-12)
    <p><i>BACKGROUND: </i> The UN's Sustainable Development Goals (SDGs) are grounded in the global ambition of "leaving no one behind". Understanding today's gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016), we measured 37 of the 50 ...
  • Does Religion Matter? Italians' Responses towards Muslim and Christian Arab Immigrants as a function of their Acculturation Preferences 

    Matera, Camilla; Picchiarini, Anna; Olsson, Maria; Brown, Rupert (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-12)
    A 2 × 2 × 2 experiment examined the role of immigrants’ religion and perceived acculturation strategy on majority members’ attitudes. Acculturation strategies were manipulated along the two dimensions of contact and culture maintenance. Italian majority members (N = 247) read fictitious but seemingly real interviews with Arab immigrants, in which the immigrants’ religion (Muslim vs. Christian) and ...
  • Stroma-induced phenotypic plasticity offers phenotype-specific targeting to improve melanoma treatment 

    Seip, Kotryna; Jørgensen, Kjetil Nordbø; Haselager, Marco Vincent; Albrecht, Marco; Haugen, Mads Haugland; Egeland, Eivind Valen; Lucarelli, Philippe; Engebråten, Olav; Sauter, Thomas; Mælandsmo, Gunhild Mari; Prasmickaite, Lina (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-18)
    Cancer cells' phenotypic plasticity, promoted by stromal cells, contributes to intra-tumoral heterogeneity and affects response to therapy. We have disclosed an association between fibroblast-stimulated phenotype switching and resistance to the clinically used BRAF inhibitor (BRAFi) vemurafenib in malignant melanoma, revealing a challenge in targeting the fibroblast-induced phenotype. Here we compared ...
  • Role of Oestrogen α Receptors in Sociosexual Behaviour in Female Rats Housed in a Seminatural Environment 

    Snoeren, Eelke; Antonio-Cabrera, E; Spiteri, Thierry Jean P; Musatov, S; Ogawa, S; Pfaff, DW; Ågmo, Anders j (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-28)
    The present study investigated the role of oestrogen receptor (ER)α in the ventromedial nucleus of the hypothalamus (VMN), the preoptic area (POA), the medial amygdala (MePD) and the bed nucleus of stria terminalis (BNST) in sociosexual behaviour in female rats. This was conducted in two sets of experiments, with the VMN and POA investigated in the first set, and the MePD and BNST in the second set. ...
  • Physical exercise and chronic pain in university students 

    Grasdalsmoen, Michael; Engdahl, Bo Lars; Fjeld, Mats Kirkeby; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Eriksen, Hege Randi; Lønning, Kari Jussie; Sivertsen, Børge (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)
    <i>Background</i> - Physical inactivity and chronic pain are both major public health concerns worldwide. Although the health benefits of regular physical exercise are well-documented, few large epidemiological studies have investigated the association between specific domains of physical exercise and chronic pain in young adults. We sought to investigate the association between frequency, intensity ...
  • Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study 

    Ree, Anne Hansen; Nygaard, Vigdis; Pedersen, Kjetil Boye; Heinrich, Daniel; Dueland, Svein; Bergheim, Inger Riise; Johansen, Christin; Beiske, Klaus; Negård, Anne; Lund-Iversen, Marius; Nygaard, Vegard; Hovig, Eivind; Nakken, Sigve; Nasser, Salah; Julsrud, Lars; Reisse, Claudius; Ruud, Espen Asak; Kristensen, Vessela N.; Flørenes, Vivi Ann; Geitvik, Gry; Lingjærde, Ole Christian; Børresen-Dale, Anne-Lise; Russnes, Hege Elisabeth Giercksky; Mælandsmo, Gunhild Mari; Flatmark, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-25)
    <i>Background</i>: In precision cancer medicine, the challenge is to prioritize DNA driver events, account for resistance markers, and procure sufficient information for treatment that maintains patient safety. The MetAction project, exploring how tumor molecular vulnerabilities predict therapy response, first established the required workflow for DNA sequencing and data interpretation (2014–2015). ...
  • Har jordmødre og helsesøstre i Nord-Norge nødvendig kunnskap om det essensielle sporstoffet jod og om jodstatus blant gravide og ammende kvinner? MISA 2-undersøkelsen 2017–2018 

    Nygård, Marie Engdal (Master thesis; Mastergradsoppgave, 2018-06-27)
    Sammendrag Bakgrunn: Mild til moderat jodmangel er påvist hos gravide og ammende kvinner i Norge, noe som kan påvirke hjerneutviklingen til fosteret og redusere barnets IQ. Jordmødre og helsesøstre har en sentral rolle i veiledning av utsatte grupper knyttet til svangerskap og ammeperiode. Denne studien evaluerer i hvilken grad jordmødre og helsesøstre i Nord-Norge har nødvendig kunnskap om jod ...
  • Serum lactate dehydrogenase contributes to prognostic assessment in patients with oligometastatic cancer and brain involvement 

    Nieder, Carsten; Dalhaug, Astrid; Pawinski, Adam (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01)
    <p><i>Background/Aim - </i>The aim of this study was to analyze the prognostic impact of serum lactate dehydrogenase (LDH) in patients with oligometastatic brain metastases, arbitrarily defined as max. Four brain lesions and 5 metastatic lesions overall. <p><i>Patients and Methods - </i>This was a retrospective single institution analysis. Overall, 42 patients were identified from a prospectively ...
  • Norwegian constraint-induced therapy multisite trial: Adherence to treatment protocol applied early after stroke 

    Stock, Roland; Thrane, Gyrd; Askim, Torunn; Karlsen, Gunn Marte; Langørgen, Eli; Erichsen, Anne Spendrup; Gjone, Ragna Ingeborg; Anke, Audny (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-24)
    <p><i>OBJECTIVE: </i>To investigate to what degree patients adhered to a modified constraint-induced movement therapy protocol, and to explore factors associated with the results. <p><i>DESIGN: </i>Prospective follow-up of the intervention arm in a randomized controlled trial. <p><i>SUBJECTS: </i>Twenty-four patients within 28 days after stroke. <p><i>METHODS: </i>The protocol specified 180 min ...
  • Adverse events as a measure of patient safety in cancer care 

    Haukland, Ellinor Christin (Doctoral thesis; Doktorgradsavhandling, 2020-09-11)
    “First, do no harm” is a fundamental element of health care and considered indistinguishable from the delivery of quality in health care. While cancer care has become more effective, it has also become more complex consequently increasing the risk for harm. We have assessed the extent and severity of treatment related adverse events in hospitalised cancer patients and elucidated how adverse events ...

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