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Nye registreringer

  • Creatine kinase is associated with reduced inflammation in a general population: The Tromsø study 

    Bekkelund, Svein Ivar; Johnsen, Stein Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-29)
    <p><i>Background</i>: Creatine kinase (CK) has been associated with reduced inflammation in obesity while inflammation is associated with obesity-related cardiovascular diseases. We investigated the relationship between CK and high sensitive C-reactive protein (hs-CRP) in a general population.</p> <p><i>Methods</i>: CK and hs-CRP were measured in the population-based Tromsø study that included ...
  • Knowledge, attitude and practice on diet and physical activity among mothers with young children in the Jhaukhel-Duwakot Health Demographic Surveillance Site, Nepal 

    Oli, Natalia; Vaidya, Abhinav; Pahkala, Katja; Eiben, Gabriele; Krettek, Alexandra (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-09)
    The prevalence of cardiovascular diseases is increasing in low and middle-income countries; Nepal’s population shows a high prevalence of behavioral risk factors. Our cross-sectional study in the Jhaukhel-Duwakot Health Demographic Surveillance Site (JD-HDSS), located near the capital Kathmandu, explored knowledge, attitude, and practice (KAP) of mothers with young children regarding diet and physical ...
  • From wholes to fragments to wholes—what gets lost in translation? 

    Kirkengen, Anna Luise (Journal article; Tidsskriftartikkel; Preprint; Manuskript, 2018-05-31)
    The highly demanding and, in a certain sense, unique, working conditions of general practitioners (GPs) are characterized by two phenomena: First, they involve an increasing familiarity with individual patients over time, which promotes a deepening of insight. Second, they enable the GP to encounter all kinds of health problems, which in turn facilitates pattern recognition, at both individual and ...
  • Early self-reported pain in juvenile idiopathic arthritis (JIA) is related to long-term outcomes. Results from the Nordic JIA cohort study. 

    Arnstad, Ellen Dalen; Rypdal, Veronika Gjertsen; Peltoniemi, Suvi; Herlin, T; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan; Glerup, Mia; Ekelund, Maria; Zak, Marek; Aalto, Kristiina; Nordal, Ellen Berit; Romundstad, Pål Richard; Rygg, Marite (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-28)
    <p><i>Objective</i>: To study self‐reported pain early in the disease course of juvenile idiopathic arthritis (JIA) as predictor of long‐term disease outcomes.</p> <p><i>Methods</i>: Consecutive cases of JIA with disease onset 1997‐2000 from defined geographical areas of Norway, Sweden, Finland and Denmark were prospectively enrolled in this population‐based cohort study. Self‐reported, disease‐related ...
  • Lower attendance rates in BreastScreen Norway among immigrants across all levels of socio-demographic factors: a population-based study 

    Le, Mary Thuy An; Hofvind, Solveig; Tsuruda, Kaitlyn; Braaten, Tonje; Bhargava, Sameer (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-03)
    <i>Background:</i> Several studies have shown that immigrants attend mammographic screening less frequently than non-immigrants. Studies have also shown that attendance is influenced by socio-demographic factors. We aimed to describe the relationship between socio-demographic factors and first attendance among immigrant and non-immigrant women invited to BreastScreen Norway.<p> <p><i>Methods:</i> ...
  • Safe Surgery Checklist, Patient Safety, teamwork, and Responsibility - Coequal Demands? A Focus Group Study 

    Willassen, Elin Thove; Smith Jacobsen, Inger Lise; Tveiten, Sidsel (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-28)
    The use of World Health Organization’s (WHO’s) Safe Surgery checklist is an established practice worldwide and contributes toward ensuring patient safety and collaborative teamwork. The aim of this study was to elucidate operating room nurses’ and operating room nursing students’ experiences and opinions about execution of and compliance with checklists. We chose a qualitative design with semistructured ...
  • Promoting Professional Development in Medical education: perspectives from the Norwegian Medical School in Tromsoe 

    Hovdenak, Sylvi Stenersen; Wiese, Eline F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-16)
    In international research on medical education the concepts of professionalism and professional development have been increasingly focused. The article problematizes and discusses these concepts in relation to the Aristotelian concepts of episteme, techne and phronesis. Phronesis as a form of knowledge is of fundamental importance regarding professionalism and professional development, and can be ...
  • Effect of a Fracture Liaison Service on the Rate of Subsequent Fracture Among Patients With a Fragility Fracture in the Norwegian Capture the Fracture Initiative (NoFRACT) 

    Andreasen, Camilla; Solberg, Lene Bergendal; Basso, Trude; Borgen, Tove Tveitan; Dahl, Cecilie; Wisløff, Torbjørn; Hagen, Gunhild; Apalset, Ellen M; Gjertsen, Jan-Erik; Figved, Wender; Hübschle, Lars Michael; Stutzer, Jens-Meinhard; Elvenes, Jan; Joakimsen, Ragnar Martin; Syversen, Unni; Eriksen, Erik Fink; Nordsletten, Lars; Frihagen, Frede Jon; Omsland, Tone Kristin; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-07)
    <p><i>Importance</i>: Fragility fracture is a major health issue because of the accompanying morbidity, mortality, and financial cost. Despite the high cost to society and personal cost to affected individuals, secondary fracture prevention is suboptimal in Norway, mainly because most patients with osteoporotic fractures do not receive treatment with antiosteoporotic drugs after fracture ...
  • “What matters to you?” A longitudinal qualitative study of Norwegian patients’ perspectives on their pathways with colorectal cancer 

    Hansen, Frank; Berntsen, Gro Karine Rosvold; Salamonsen, Anita (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-12)
    <p><i>Purpose</i>: Person-centred care (PCC) is a well-acknowledged goal throughout the western world both within the health care services sector and for the patients themselves. To be able to create a future health care system that includes improved PCC, we need more in-depth knowledge of what matters to patients, how “what matters” might change over time, and tentative descriptions of commonalities ...
  • Omsorg for den samfunnsnyttige kroppen 

    Boge, Jeanne; Kristoffersen, Kjell; Martinsen, Kari (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
    Den franske filosofen Michel Foucault argumenterte for at ein har styrt moderne samfunn ved hjelp av samankoplingar mellom kroppslege praksisar og vitskap. Denne styringsforma kalla han disiplinering. I denne artikkelen argumenterer me for at den politiske argumentasjonen i siste halvdel av 1800-talet og starten av 1900-talet, om å legge om frå folkeleg til borgarleg reinsemd, kan ha vore ein lekk ...
  • Pasientrapportert tilfredshet og livskvalitet etter ulike kirurgiske inngrep ved brystkreft 

    Sjåvik, Anniken (Preprint; Manuskript, 2018-09-20)
    Bakgrunn: Primær behandling ved brystkreft er kirurgi. Kirurgiske alternativer ved brystkreft er mastektomi, lumpektomi, mastektomi med primær brystrekonstruksjon (MPR) eller mastektomi med sekundær rekonstruksjon (MSR). For de fleste brystkreftpasienter vil det være flere aktuelle kirurgiske metoder. Kunnskap om postoperativ livskvalitet, tilfredshet og komplikasjoner vil da kunne være veiledende ...
  • Total and cause-specific standardized mortality ratios in patients with schizophrenia and/or substance use disorder 

    Heiberg, Ina Heidi; Jacobsen, Bjarne K.; Nesvåg, Ragnar; Bramness, Jørgen Gustav; Reichborn-Kjennerud, Ted; Næss, Øyvind; Ystrøm, Eivind; Hultman, Christina M; Høye, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-23)
    Individuals with schizophrenia or substance use disorder have a substantially increased mortality compared to the general population. Despite a high and probably increasing prevalence of comorbid substance use disorder in people with schizophrenia, the mortality in the comorbid group has been less studied and with contrasting results. We performed a nationwide open cohort study from 2009 to 2015, ...
  • Springboard to an academic career—A national medical student research program 

    Jacobsen, Geir Wenberg; Ræder, Helge; Stien, Marianne Heldal; Munthe, Ludvig Andre; Skogen, Vegard (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-30)
    Over the last decades there has been a decline in the recruitment of medical students into academia in all medical fields. Concurrently, medical research has increasingly included other disciplines in multidisciplinary convergence, introducing an unmet recruitment gap and requirement for medical researchers. To counteract the trend and recruit students to academic medicine, a national intercalated ...
  • Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy 

    Paunas, Theodora Ioana Flavia; Finne, Kenneth; Leh, Sabine; Marti, Hans-Peter; Mollnes, Tom Eirik; Berven, Frode; Vikse, Bjørn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-14)
    Background: The clinical course of IgA nephropathy (IgAN) is variable and complement activation may predict prognosis. The present study investigated whether glomerular abundance of complement proteins associates with progression to end-stage renal disease (ESRD) in patients for whom prognosis could not be predicted based on clinical variables. <br> <br> Methods: Based on data from the Norwegian ...
  • Dental caries and preterm birth: a systematic review and meta-analysis 

    Wagle, Madhu; D'Antonio, Francesco; Reierth, Eirik; Basnet, Purusotam; Trovik, Tordis A; Orsini, Giovanna; Manzoli, Lamberto; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-02)
    Objectives:<br> The primary objective of this systematic review was to evaluate the association between dental caries and preterm birth (PTB). The secondary objective was ascertaining the difference between women with dental caries who experienced PTB and those who did not with regard to decayed, missing and filled teeth (DMFT), and decayed, missing and filled surfaces (DMFS) indices. <br>M ...
  • Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis 

    Hellerud, Bernt C; Orrem, Hilde L.; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert; Fure, Hilde; Bergseth, Grete; Christiansen, Dorte; Nunn, Miles A.; Espevik, Terje; Lau, Corinna; Brandtzæg, Petter; Nielsen, Erik Waage; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-27)
    Background<br> Fulminant meningococcal sepsis, characterized by overwhelming innate immune activation, mostly affects young people and causes high mortality. This study aimed to investigate the effect of targeting two key molecules of innate immunity, complement component C5, and co-receptor CD14 in the Toll-like receptor system, on the inflammatory response in meningococcal sepsis.<p> Methods ...
  • Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy 

    Abraityte, Aurelija; Lunde, Ida Gjervold; Askevold, Erik Tandberg; Michelsen, Annika E.; Christensen, Geir Arve; Aukrust, Pål; Yndestad, Arne; Fiane, Arnt; Andreassen, Arne; Aakhus, Svend; Dahl, Christen Peder; Gullestad, Lars; Broch, Kaspar; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-14)
    The Wingless (Wnt) pathway has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). To explore the role of Wnt modulators Wnt5a and sFRP3 in DCM patients we analyzed the expression of Wnt5a and sFRP3 in plasma and myocardium of DCM patients and evaluated their effects on NFAT luciferase activity in neonatal mouse cardiomyocytes. Elevated circulating Wnt5a (n = 102) was associated ...
  • Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo 

    Genster, Ninette; Østrup, Olga; Schjalm, Camilla; Mollnes, Tom Eirik; Cowland, Jack B.; Garred, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-20)
    Ficolins are a family of pattern recognition molecules that are capable of activating the lectin pathway of complement. A limited number of reports have demonstrated a protective role of ficolins in animal models of infection. In addition, an immune modulatory role of ficolins has been suggested. Yet, the contribution of ficolins to inflammatory disease processes remains elusive. To address this, ...
  • The alternative complement pathway is dysregulated in patients with chronic heart failure 

    Shahini, Negar; Michelsen, Annika E.; Nilsson, Per H.; Ekholt, Karin; Gullestad, Lars; Broch, Kaspar; Dahl, Christen P.; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Yndestad, Arne; Louwe, Mieke C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-14)
    The complement system, an important arm of the innate immune system, is activated in heart failure (HF). We hypothesized that HF patients are characterized by an imbalance of alternative amplification loop components; including properdin and complement factor D and the alternative pathway inhibitor factor H. These components and the activation product, terminal complement complex (TCC), were measured ...
  • Fatal poisonings in Northern Finland: causes, incidence, and rural-urban differences 

    Koskela, Lauri; Raatiniemi, Lasse; Bakke, Håkon Kvåle; Ala-Kokko, Tero; Liisanantti, Janne (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-08)
    Background: In this study we evaluate differences between rural and urban areas in the causes and incidence of fatal poisonings. <p> Methods: Data from all fatal poisonings that occurred in Northern Finland from 2007 to 2011 were retrieved from Cause of Death Registry death certificates provided by Statistics Finland. The demographics and causes of fatalities were compared between rural and urban ...

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