Now showing items 1-20 of 6094

    • A 12-month follow-up of a transdiagnostic indicated prevention of internalizing symptoms in school-aged children: The results from the EMOTION study. 

      Løvaas, Mona Elisabeth S; Lydersen, Stian; Sund, Anne Mari; Neumer, Simon-Peter; Martinsen, Kristin Dagmar; Holen, Solveig; Patras, Joshua; Rasmussen, Lene-Mari Potulski; Adolfsen, Frode; Reinfjell, Trude (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-22)
      <i>Background</i> - Anxious and depressive symptoms in youth are highly prevalent, are often comorbid and have a high rate of relapse. Preventive interventions are promising, but follow-up results are lacking. The transdiagnostic EMOTION program is an indicated preventive cognitive behavioral therapy (CBT) intervention targeting children aged 8–12 years.<p> <p><i>Methods</i> - The present study ...
    • 14th International Symposium on Cells of the Hepatic Sinusoid 

      Smedsrød, Bård (Book; Bok, 2008-08-31)
      Abstract book of the symposium
    • The 2014-2016 Ebola Epidemic in West Africa. How did cultural factors contribute to an escalation of the outbreak? 

      Granerud, Hannah Skjellet (Master thesis; Mastergradsoppgave, 2018-06-04)
      Background The 2014-2016 Ebola epidemic is the biggest known outbreak since 1976. The transmission from a bush animal to one human eventually caused 28 652 cases and 11 325 deaths. It is necessary to investigate how one case could cause that many infected people and deaths, and this study aims to identify the most important cultural factors that contributed to these high numbers. Method This ...
    • 24 timers posisjonering for barn med spastisk quadriplegi. Et foreldreperspektiv 

      Henninen, Anita Pettersen (Master thesis; Mastergradsoppgave, 2010-05-12)
      Studien er en kvalitativ undersøkelse og et kvalitativt forskningsintervju er benyttet som metode i tilvirkningen av data. Undersøkelsen har fokus mot foreldres erfaringer ved å skulle gjennomføre 24 timers posisjonering, inkludert tilpasset sovesystem på natten, for eget barn. Det er relativt lite erfaring her i Norge med å tenke posisjonering hele døgnet for barn med store bevegelsesvansker, og ...
    • 3-Weeks of Exercise Training Increases Ischemic-Tolerance in Hearts From High-Fat Diet Fed Mice 

      Boardman, Neoma Tove; Rossvoll, Line; Lund, Jim; Hafstad, Anne Dragøy; Aasum, Ellen (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-02)
      Physical activity is an efficient strategy to delay development of obesity and insulin resistance, and thus the progression of obesity/diabetes-related cardiomyopathy. In support of this, experimental studies using animal models of obesity show that chronic exercise prevents the development of obesity-induced cardiac dysfunction (cardiomyopathy). Whether exercise also improves the tolerance to ...
    • 3T3 cell lines stably expressing Pax6 or Pax6(5a): a new tool used for identification of common and isoform specific target genes. 

      Kiselev, Yury; Eriksen, Tonje Engevik; Forsdahl, Siri; Nguyen, Lan Huong Thi; Mikkola, Ingvild (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Pax6 and Pax6(5a) are two isoforms of the evolutionary conserved Pax6 gene often co-expressed in specific stochiometric relationship in the brain and the eye during development. The Pax6(5a) protein differs from Pax6 by having a 14 amino acid insert in the paired domain, causing the two proteins to have different DNA binding specificities. Difference in functions during development is proven by the ...
    • A 4-Week Intervention Involving Mobile-Based Daily 6-Minute Micro-Sessions of Functional High-Intensity Circuit Training Improves Strength and Quality of Life, but Not Cardio-Respiratory Fitness of Young Untrained Adults 

      Sperlich, Billy; Hahn, Lea-Sofie; Edel, Antonia; Behr, Tino; Helmprobst, Julian; Leppich, Robert; Wallmann-Sperlich, Birgit; Holmberg, Hans-Christer (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-09)
      The present study was designed to assess the psycho-physiological responses of physically untrained individuals to mobile-based multi-stimulating, circuit-like, multiplejoint conditioning (Circuit<sub>HIIT</sub>) performed either once (1xCircuit<sub>HIIT</sub>) or twice (2xCircuit<sub>HIIT</sub>) daily for 4 weeks. In this single-center, two-arm randomized, controlled study, 24 men and women (age: ...
    • A 4-year follow-up of patients with medication-overuse headache previously included in a randomized multicentre study. 

      Salvesen, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The aim of this study was to evaluate the longterm outcome in 61 patients with medication-overuse headache (MOH) who 4 years previously had been included in a randomized open-label prospective multicentre study. Sixty patients still alive after 4 years were invited to a follow-up investigation. Fifty patients (83%) participated. Sixteen visited a neurologist, 22 were interviewed through telephone, ...
    • The 5-HT1E receptor. Receptor structure and ligand interactions. 

      Gabrielsen, Mari (Master thesis; Mastergradsoppgave, 2006-12-08)
      5-HT (5-Hydroxytryptamine; Serotonin) is the neurotransmitter with the highest number of known receptors in humans, and the importance of 5-HT is also reflected in the number of species using 5-HT as a signalling molecule and the number of 5-HT receptors found within each species. 15 human 5-HT receptors have at this date been characterised and classified into seven 5-HT receptor families. Six of ...
    • 5-type HPV mRNA versus 14-type HPV DNA test: test performance, over-diagnosis and overtreatment in triage of women with minor cervical lesions 

      Westre, Bjørn; Giske, Anita; Guttormsen, Hilde; Sørbye, Sveinung Wergeland; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-07)
    • 50 siste reinnleggelser. Analyse av 50 siste reinnleggelser ved Hjertemedisinsk avdeling, UNN Tromsø. 

      Lorentzen, Ida Christine (Master thesis; Mastergradsoppgave, 2018-06-03)
      Bakgrunn: Reinnleggelse av pasienter er en hyppig brukt kvalitetsindikator i helsevesenet. Reinnleggelser kan være uttrykk for god behandling; for eksempel tett oppfølging av pasienter med kronisk sykdom, såkalt «åpen retur», men kan også være uttrykk for uhensiktsmessige pasientforløp eller kvalitetssvikt. Formålet med studien var å se om man kan identifisere områder for forbedring ved å gjennomgå ...
    • 6-thioguanin som monoterapautisk behandling av akutt leukemi hos voksne 

      Fjellhøy, Åse-Gunn; Steene, Hege Liljedahl (Master thesis; Mastergradsoppgave, 2004)
    • ABC-transportørenes kliniske betydning 

      Bremnes, Thomas (Master thesis; Mastergradsoppgave, 2013-06-02)
      Multi-legemiddelresistens (multidrug resistance, MDR) er resistens mot flere strukturelt uavhengige kjemoterapimidler. Dette er spesielt ett problem for behandling av kreft fordi kreftceller kan danne resistens mot flere midler samtidig. Slik resistens utvikles ved hjelp av flere cellulære mekanismer. Den mest undersøkte og oftest assosierte metoden er via økt uttrykk av ATP-bindende kassett ...
    • ABC-transportører 

      Slåtsve, Arne Martin (Mastergradsoppgave; Master thesis, 2009-09-15)
      ABC (ATP-binding cassette)-transportører er store, evolusjonsmessig høykonserverte membranproteiner som er påvist i alle arter fra prokaryoter til komplekse organismer. ABC-transportørene muliggjør energiavhengig transport av spesifikke substrater gjennom cellemembraner. Blant substratene vi kjenner er lipider, karbohydrater, peptider, vitaminer, steroidhormoner, xenobiotika og medikamenter. ...
    • ABCC9-related intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9 

      Smeland, Marie Falkenberg; McClenaghan, Conor; Roessler, Helen I.; Savelberg, Sanne; Hansen, Geir Åsmund Myge; Hjellnes, Helene; Arntzen, Kjell Arne; Müller, Kai Ivar; Dybesland, Andreas R.; Harter, Theresa; Sala-Rabanal, Monica; Emfinger, Chris H.; Huang, Yan; Singareddy, Soma S.; Gunn, Jamie; Wozniak, David F.; Kovacs, Attila; Massink, Maarten; Tessadori, Federico; Kamel, Sarah M.; Bakkers, Jeroen; Remedi, Maria S.; Van Ghelue, Marijke; Nichols, Colin G.; van Haaften, Gijs (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-01)
      Mutations in genes encoding K<sub>ATP</sub> channel subunits have been reported for pancreatic disorders and Cantú syndrome. Here, we report a syndrome in six patients from two families with a consistent phenotype of mild intellectual disability, similar facies, myopathy, and cerebral white matter hyperintensities, with cardiac systolic dysfunction present in the two oldest patients. Patients are ...
    • Abdominal aortic aneurysms, or a relatively large diameter of non-aneurysmal aortas, increase total and cardiovascular mortality: the Tromsø study. 

      Forsdahl, Signe Helene; Solberg, Steinar; Singh, Kulbir; Jacobsen, Bjarne Koster (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      Background: In a population-based study in Tromsø, Norway, the authors assessed whether an abdominal aortic aneurysm (AAA) or the maximal infrarenal aortic diameter in a non-aneurismal aorta influence total and cardiovascular disease (CVD) mortality. Methods: A total of 6640 men and women, aged 25–84 years, were included in a 10-year mortality follow-up: 345 subjects with a diagnosed AAA and ...
    • Abdominal symptoms in general practice: Frequency, cancer suspicions raised, and actions taken by GPs in six European countries. Cohort study with prospective registration of cancer 

      Holtedahl, Knut A.; Borgquist, Lars; Donker, Gé A.; Buntinx, Frank; Weller, David; Braaten, Tonje; Hjertholm, Peter; Månsson, Jörgen; Strandberg, Eva Lena; Campbell, Christine; Ellegaard, Lisbeth; Parajuli, Ranjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06)
      Background<br> Abdominal symptoms are diagnostically challenging to general practitioners (GPs): although common, they may indicate cancer. In a prospective cohort of patients, we examined abdominal symptom frequency, initial diagnostic suspicion, and actions of GPs in response to abdominal symptoms.<p> Methods<br> Over a 10-day period, 493 GPs in Norway, Denmark, Sweden, Belgium, the Netherlands, ...
    • The ability of the strengths and difficulties questionnaire to detect mental health disorders in a child and adolescent outpatient clinic in Northern-Norway 

      Sæther, Guri; Moe, Therese Fjeldmo (Master thesis; Mastergradsoppgave, 2010-05-03)
      The aim of the study was to examine the ability of the Strength and Difficulties Questionnaire (SDQ) to detect mental health disorders among patients referred to a child and adolescent outpatient clinic. The sample consisted of 100 participants between 5 and 17 years referred to an outpatient clinic in Northern-Norway. The SDQ-generated diagnostic predictions were compared to a gold standard to ...
    • Abort i andre trimester. Ei femårig retrospektiv studie 

      Skjeldal, Hege (Master thesis; Mastergradsoppgave, 2006)
    • Abridged risk information: Effects of warning labels on snus packages 

      Nilsen, Connie Villemo (Doctoral thesis; Doktorgradsavhandling, 2020-02-28)
      <i>Background</i> - We screened the sparse literature on how health warnings on snus products affect risk perception and use intentions, and contributed with two experimental studies on the topic.<p> <p><i> Methods</i> - First, we examined previous studies on health warnings on smokeless tobacco in a systematic review, studied the manipulations in exposure studies, and systematized the outcome ...