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    • GABAA subunit single nucleotide polymorphisms show sex-specific association to alcohol consumption and mental distress in a Norwegian population-based sample 

      Moe, Jenny Skumsnes; Bolstad, Ingeborg; Mørland, Jørg Gustav; Bramness, Jørgen Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-14)
      Little is known about genetic influences on the relationship between alcohol consumption and mental distress in the general population, where the majority report consumption and distress far below diagnostic thresholds. This study investigated single nucleotide polymorphisms (SNPs) from candidate gene studies on alcohol use disorder and depressive disorders, for association with alcohol consumption ...

    • The GABAB Receptor - Structure, Ligand Binding and Drug Development 

      Evenseth, Linn Samira Mari; Gabrielsen, Mari; Sylte, Ingebrigt (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-07)
      The γ-aminobutyric acid (GABA) type B receptor (GABA<sub>B</sub-R) belongs to class C of the G-protein coupled receptors (GPCRs). Together with the GABA<sub>A</sub> receptor, the receptor mediates the neurotransmission of GABA, the main inhibitory neurotransmitter in the central nervous system (CNS). In recent decades, the receptor has been extensively studied with the intention being to understand ...

    • Gammel, sier du? Hurra! 

      Gorecka, Marta Maria (Chronicle; Kronikk, 2015)

    • Gangvansker hos barn med cerebral parese og fysioterapi : samhandling og mulighet for endring i bevegelseskvalitet : en kvalitativ observasjonsstudie 

      Thon, Tonje (Master thesis; Mastergradsoppgave, 2012-05-15)
      Bakgrunn for studien er et ønske om å forstå mer av hva som skjer i klinisk praksis basert på egne praksiserfaringer, forekomst av cerebral parese og eksisterende forskning på området. Hensikten er å analysere og dokumentere hva som skjer i fysioterapibehandling av barn med cerebral parese som har gangvansker. I tillegg er hensikten å se om det skjer endringer i bevegelseskvalitet i behandlingene, ...

    • Gaps in risk perceptions are barriers to doctor-patient communication about CAM 

      Salamonsen, Anita; Wiesener, Solveig (Conference object; Konferansebidrag, 2017)
      Studies have revealed differing perceptions of risk associated with use of conventional and alternative treatments among medical doctors and CAM users. This pilot study explored such differing risk perceptions and their possible influence on doctor CAM user communication.

    • Garbage codes in the Norwegian Cause of Death Registry 1996-2019 

      Ellingsen, Christian Lycke; Alfsen, Glenny Cecilie; Ebbing, Marta; Pedersen, Anne Gro; Sulo, Gerhard; Vollset, Stein Emil; Braut, Geir Sverre (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-07)
      Background: Reliable statistics on the underlying cause of death are essential for monitoring the health in a population. When there is insufcient information to identify the true underlying cause of death, the death will be classifed using less informative codes, garbage codes. If many deaths are assigned a garbage code, the information value of the cause-of-death statistics is reduced. The aim ...

    • GARP promotes the proliferation and therapeutic resistance of bone sarcoma cancer cells through the activation of TGF-beta 

      Carrillo-Gálvez, Ana Belén; Quintero, Juan Esteban; Rodríguez, René; Menéndez, Sofía T.; González, M. Victoria; Blanco-Lorenzo, Verónica; Allonca, Eva; Farias, Virgínea de Araújo; González-Correa, Juan Elías; Erill-Sagalés, Nadina; Martínez-Zubiaurre, Iñigo; Hellevik, Turid; Sánchez-Hernández, Sabina; Muñoz, Pilar; Zurita, Federico; Martín, Francisco; Rodríguez-Manzaneque, Juan Carlos; Anderson, Per (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-17)
      Sarcomas are mesenchymal cancers with poor prognosis, representing about 20% of all solid malignancies in children, adolescents, and young adults. Radio- and chemoresistance are common features of sarcomas warranting the search for novel prognostic and predictive markers. GARP/LRRC32 is a TGF-β-activating protein that promotes immune escape and dissemination in various cancers. However, if GARP ...

    • Gas embolism during surgery. A complement mediated condition? 

      Storm, Benjamin Stage; Christiansen, Dorte; Dybwik, Knut; Mollnes, Tom Eirik; Nielsen, Erik Waage (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-01)
      <p><i>Introduction</i>: Venous air embolism (VAE) may arise during surgical procedures. VAE might be complicated with a systemic inflammatory response, disseminated intervascular coagulation, multi-organ failure and cardiovascular collapse. During a short time-span, three patients at our institution developed signs of VAE in conjunction with gynecological surgery. One died, one developed severe ...

    • Gastric Cancer surgery at the University Hospital of Northern Norway from 2007 to 2017, from open to minimal invasive surgery 

      Rosvold, Sondre (Master thesis; Mastergradsoppgave, 2020-11-12)
      Background: Gastric cancer is one of the leading causes of cancer related death, world-wide. The most common type is adenocarcinoma, which account for 95% of all gastric tube cancers. Curative treatment always includes surgery and, with few exceptions, neoadjuvant and adjuvant chemotherapy. The surgical treatment of gastric cancer has changed from open to minimally invasive surgery in many centers ...

    • Gastrointestinal carriage of Klebsiella pneumoniae in a general adult population: a cross-sectional study of risk factors and bacterial genomic diversity 

      Raffelsberger, Niclas Peter; Hetland, Marit Andrea Klokkhammer; Svendsen, Kristian; Småbrekke, Lars; Löhr, Iren Høyland; Andreassen, Lotte; Brisse, Sylvain; Holt, Kathryn E.; Sundsfjord, Arnfinn; Samuelsen, Ørjan; Gravningen, Kirsten Midttun (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-28)
      Antibiotic resistant <i>Klebsiella pneumoniae</i> is a leading public health threat and gastrointestinal carriage is an established risk factor for subsequent infections during hospitalization. Our study contributes new knowledge of risk factors for gastrointestinal carriage and the genomic population structure of <i>K. pneumoniae</i> colonizing humans in a representative sample of a general population ...

    • Gastrointestinal Quality of Life in Gastroesophageal Reflux Disease: A Systematic Review 

      Fuchs, Karl-Hermann; Musial, Frauke; Eypasch, Ernst; Meining, Alexander (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07)
      Background: The Gastrointestinal Quality of Life Index (GIQLI) is a well-established instrument for the assessment of quality of life (QOL) in gastrointestinal (GI) diseases. The purpose of this literature review was to investigate QOL by means of GIQLI in patients with gastroesophageal reflux disease (GERD) prior to any interventional therapy. There are several reports on GIQLI data; however, ...

    • Gastrointestinal stromal tumor (GIST) operert ved UNN Tromsø 1999-2019: forekomst, karakteristika og overlevelse 

      Olsen, Ida Zhang (Master thesis; Mastergradsoppgave, 2020-08-28)
      Bakgrunn: Gastrointestinal stromal tumor (GIST) er den vanligste mesenkymale svulsten i fordøyekseskanalen, og ble definert som en egen svulsttype rundt 1999. Tidligere trodde man at denne svulsttypen utgikk fra muskulatur eller nervevev, men man vet nå at de utgår fra såkalte pacemakerceller kalt Interstitiale Cajalske Celler (ICC). De forekommer oftest i ventrikkel og tynntarm, men svulster kan ...

    • Gateway to Recovery: A Comparative Analysis of Stroke Patients’ Experiences of Change and Learning in Norway and Denmark 

      Pallesen, Hanne; Aadal, Lene; Moe, Siri; Arntzen, Cathrine (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-17)
      <i>Objectives</i>: The recovery process is reported by stroke survivors to be a change process fraught with crises and hazard. Interaction with health professionals and others may play a central role in establishing renewed control over life.<p> <p><i>Research Questions</i>: (1) How do patients handle and overcome experienced changes after stroke? (2) How do they experience the support to ...

    • Gemcitabine-containing liposomes 

      Gravem, Hilde (Master thesis; Mastergradsoppgave, 2006-06-16)
      Gemcitabine, an anticancer agent, is currently in clinical use for the treatment of several types of cancer. Unfortunately, gemcitabine is rapidly metabolised with a short plasma half-life and its cytostatic action is strongly exposure-time dependent. In order to achieve the required concentration over sufficient periods of time, repeated application of relatively high doses is required. This, in ...

    • Gender at Work Across Nations: Men and Women Working in Male-Dominated and Female-Dominated Occupations are Differentially Associated with Agency and Communion 

      Froehlich, Laura; Olsson, Maria; Dorrough, Angela R.; Martiny, Sarah (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-24)
      Occupational gender segregation is a worldwide phenomenon. Research from Western regions such as the United States and Europe shows that the observation of occupational gender segregation can perpetuate gender stereotypes (social role theory; men are ascribed agentic traits, whereas women are ascribed communal traits). However, predictions from social role theory have not been well‐tested in non‐Western ...

    • Gender differences in alcohol onset and drinking frequency in adolescents: an application of the theory of planned behavior 

      Kyrrestad, Henriette; Mabille, Geraldine; Adolfsen, Frode; Koposov, Roman A; Martinussen, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-28)
      The Theory of Planned Behavior (TPB) is a model utilized to predict human behavior that was used to examine adolescents’ alcohol drinking behavior (onset and frequency of drinking). Longitudinal data collected over a 2 year period from Norwegian junior high school students (N ¼ 1,563) was used. Multilevel structural equation models was used to examine the utility of the TPB to explain variance ...

    • Gender differences in association between uric acid and all-cause mortality in patients with chronic heart failure 

      Stubnova, Viera; Os, Ingrid; Høieggen, Aud; Solbu, Marit Dahl; Grundtvig, Morten; Westheim, Arne; Atar, Dan; Waldum-Grevbo, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-05)
      <p><i>Background - </i>Elevated serum uric acid (SUA) is associated with poor prognosis in patients with cardiovascular disease, yet it is still not decided whether the role of SUA is causal or only reflects an underlying disease. The purpose of the study was to investigate if SUA was an independent predictor of 5-year all-cause mortality in a propensity score matched cohort of chronic heart failure ...

    • Gender differences in hearts subjected to decreased NO-production and elevated blood pressure 

      Kildal, Simon; Ludvigsen, Stian; Norvik, Jon Viljar; Johansen, David; Ytrehus, Kirsti (Master thesis; Mastergradsoppgave, 2016-10-31)
      Hypertension is one of the most important risk factors for heart failure in the general population. Hypertensive heart failure is associated with heart failure with preserved ejection fraction (HFpEF). Women have an increase proportion of HFpEF compared to men. Endothelial dysfunction thereby reduced NO production is proposed to play an important role in the pathophysiology of HFpEF. A suggested ...

    • Gender differences in prevalence and associations for use of CAM in a large population study. 

      Kristoffersen, Agnete Egilsdatter; Stub, Trine; Salamonsen, Anita; Musial, Frauke; Hamberg, Katarina (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-12-03)

    • Gender differences in the bidirectional relationship between alcohol consumption and sleeplessness: the Tromsø study 

      Rognmo, Kamilla; Bergvik, Svein; Rosenvinge, Jan H; Bratlid, Katja Lovise; Friborg, Oddgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-29)
      <i>Background</i> - The degree to which the relationship between alcohol use and sleeplessness is unidirectional or reciprocal is unclear due to great variation among the results of previous studies. The aim of the present study was to investigate if the relationship between alcohol use and sleeplessness is bidirectional by exploring how the change in and stability of alcohol use were related to ...