Det helsevitenskapelige fakultet: Recent submissions
Now showing items 1-20 of 10780
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Assessing primary information sources and knowledge of menstruration among adolescent girls in Nepal: A cross-sectional study
(Master thesis; Mastergradsoppgave, 2023-12-01)<p>Background: Adolescent girls, aged 10-19, undergo a critical physiological transition during which menarche and monthly menstrual cycles signify normal physiological functioning. In Nepal, cultural myths and taboos stigmatize menstruation, contributing to misconceptions that lead to self-isolation, social exclusion, and negative impacts on physical and mental health. The study aims to assess ... -
Impact of competition on profit and revenue of pharmacies in Norway
(Master thesis; Mastergradsoppgave, 2023-12-01)<p>Introduction: Since 2001, due to the change in the Pharmacy Act, the accessibility of pharmacies to the public has considerably increased due to the increase in the number of pharmacies owned by chain wholesalers. In terms of pharmaceutical brands, competition serves as a driving force that compels brands to make new, effective, and enhanced medicines while encouraging generic companies to provide ... -
Association Between Smoking and Cognitive Function Based on Atrial Fibrillation Status: The Tromsø Study
(Master thesis; Mastergradsoppgave, 2022-11-30)<p>Background: According to World Health Organization (WHO), the global tobacco smoking prevalence is 22.3% (36.7% for men and 7.8% for women). Cigarette smoking is a risk factor for cancer, cardiovascular diseases, and cognitive decline. The association of smoking and cognitive decline is well documented. Whitehall II Cohort study, Doetinchem Cohort study and many other studies have found that ... -
Review article: A scoping review of human factors in avalanche decision-making
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-26)The interest in understanding the human aspects of avalanche risk mitigation has steadily grown over the past few decades. Between 2001–2011, 11 research papers on decision-making in avalanche terrain were published in peer-reviewed journals. Between 2012–2022, this number rose to 55. These papers have been authored by researchers from various disciplines and publications in journals across different ... -
Prevalence of obesity and its associations with other cardiovascular risk factors in Russia. Insights from the Know Your Heart Study
(Doctoral thesis; Doktorgradsavhandling, 2024-12-16)<p><i>Background.</i> The prevalence of obesity has reached epidemic proportions worldwide. Obesity is a risk factor for the development of cardiovascular disease (CVD) and predisposes to hypertension, type 2 diabetes mellitus (T2D) and dyslipidemia. The simultaneous presence of visceral adiposity and these cardiometabolic disorders, also known as the metabolic syndrome, accelerates atherosclerotic ... -
Plasma phosphorylated-tau217 is increased in Niemann–Pick disease type C
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-25)Niemann–Pick disease type C and Alzheimer’s disease are distinct neurodegenerative disorders that share the presence of neurofibrillary tangle pathology. In this multicentre study, we measured plasma phosphorylated-tau217 in controls (n = 60), Niemann–Pick disease type C (n = 71) and Alzheimer’s disease (n = 30 positive for amyloid and negative for tau in CSF [A+ T−] and n = 30 positive for both ... -
Menopausal hormone therapy and incidence, mortality, and survival of breast cancer subtypes: a prospective cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-04)Background Menopausal hormone therapy (MHT) is associated with an increased risk of postmenopausal breast cancer, predominantly the luminal A-like subtype. The impact of MHT on deaths from breast cancer subtypes is less understood. This study aimed to explore associations between MHT use and the incidence, mortality, and survival of intrinsic-like breast cancer subtypes.<p> <p>Methods Data from ... -
Timely empirical antibiotic therapy against sepsis in a rural Norwegian ambulance service: a prospective cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-31)Background Early diagnosis and antibiotic therapy in patients with sepsis reduce morbidity and mortality, thus pre-hospital management is likely to affect patient outcomes. Pre-hospital administration may increase the risk of unnecessary use of broad-spectrum antibiotics, but identification of an infectious focus enables more targeted antibiotic therapy. The aim of this study was to investigate ... -
The patient’s voice: a cross-sectional study of physical health and disability in juvenile idiopathic arthritis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-18)Background With increasing focus on patient-reported outcome measures (PROMs) in chronic rheumatic diseases, we aimed to evaluate the self-reported physical and psychosocial health in children with juvenile idiopathic arthritis (JIA) compared to matched population-based controls. Furthermore, we aimed to study the association of patient and physician-reported outcome measures in JIA with ... -
PFAS exposure is associated with an unfavourable metabolic profile in infants six months of age
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-01)Exposure to perfluoroalkyl substances (PFAS) are reported to have numerous negative health effects and children are especially vulnerable. The aim of this study was to investigate whether maternal and infant PFAS burden have any impact on prenatal and postnatal growth, liver and lipid parameters in infants at age six months. Data on diet and growth parameters, as well as blood samples were collected ... -
Exploring the unconventional: health professionals’ experiences into medication-free treatment for patients with severe mental illness
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-14)Background In January 2017, the Norwegian government mandated the establishment of an inpatient unit for“medication-free treatment” for patients with severe mental illness at the University Hospital of North Norway in Tromsø. This study aims to explore the employees’ experiences with this unit.<p> <p>Method Focus group interviews were conducted October 2021 – February 2022. For analysis, the ... -
COVID-19 morbidity, severity, and mortality in a population-based sample of adults in Arkhangelsk, Northwest Russia
(Doctoral thesis; Doktorgradsavhandling, 2024-12-12)<p><i>Objective</i> To investigate seroprevalence, spectrum of COVID-19 cases and factors associated with COVID-19 morbidity, severity, and mortality in a population-based sample of adults in Arkhangelsk, Northwest Russia. <p><i>Methods</i> Participants in the Know Your Heart study (2015-2017) were enrolled in a COVID-19 seroprevalence study (n=1348) in 2021 and followed up for COVID-19 diagnosis, ... -
Initial interpretation scores of screening mammograms and cancer detection in BreastScreen Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-12)Purpose - To explore the association between radiologists’ interpretation scores, early performance measures and cumulative reading volume in mammographic screening.<p> <p>Method - We analyzed 1,689,731 screening examinations (3,379,462 breasts) from BreastScreen Norway 2012–2020, all breasts scored 1–5 by two independent radiologists. Score 1 was considered negative/benign and score ≥2 positive ... -
The Role of Health Informatics Research: A Case of a Large-Scale Implementation in Norway
(Chapter; Bokkapittel, 2024)Many see the role of health informatics research as informing the development and implementation of information technology in clinical practice. The aim of this study is to see if this role is realized in the ongoing implementation of a large-scale health information system in central Norway. By doing a document analysis of the planning documents for the implementation, we assess to what extend ... -
The Role of Health Informatics Research: A Case of a Large-Scale Implementation in Norway
(Chapter; Bokkapittel, 2024)Many see the role of health informatics research as informing the development and implementation of information technology in clinical practice. The aim of this study is to see if this role is realized in the ongoing implementation of a large-scale health information system in central Norway. By doing a document analysis of the planning documents for the implementation, we assess to what extend ... -
Motor dominance and movement-outcome congruency influence the electrophysiological correlates of sensory attenuation for self-induced visual stimuli
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-16)This study explores the impact of movement-outcome congruency and motor dominance on the action-associated modulations of early visual event-related potentials (ERPs). Employing the contingent paradigm, participants with varying degrees of motor dominance were exposed to stimuli depicting left or right human hands in the corresponding visual hemifields. Stimuli were either passively observed or ... -
Kultur i motvind? Kvener/norskfinner om utfordringer på veien mot en kvensk/norskfinsk identitet
(Chapter; Bokkapittel, 2024-11-04)Dette kapittelet tar for seg utfordringer på veien mot en kvensk/norskfinsk identitet, basert på kvalitative intervjuer med 25 personer med kvensk/norskfinsk bakgrunn. Vi drøfter disse personenes erfaringer og synspunkter med hovedvekt på kumulativ diskriminering som teoretisk forståelsesramme. Kumulativ diskriminering innebærer at diskrimineringserfaringer kan hope seg opp og videreføres til nye ... -
Who skis where, when?
(Doctoral thesis; Doktorgradsavhandling, 2024-12-12)<p>Backcountry skiing has emerged as a so-called adventure sport in recent decades and has had a considerable social and economic impact in Northern Norway. Tourism, Norway's fifth-largest export industry, is experiencing significant growth and is especially important for small communities. However, recreation in avalanche terrain comes at a cost due to the risk of avalanches. Consequently, any ... -
Social isolation and loneliness and their association with all-cause mortality. A population-based longitudinal study in Norway: The Tromsø Study 1994–2023
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-20)Objectives - Loneliness and social isolation are associated with increased mortality, but few studies have assessed this association over long time in young adults.<p> <p>Methods - The study sample comprised 9061 women and 8735 men aged 25 to 69 years who participated in the Tromsø4 survey (1994–95, baseline) of the Tromsø Study, Norway. A subset of the study sample also attended the Tromsø5 ... -
Dentists' Treatment Decisions Concerning Restorations in Adult Patients in North Norway: A Cross-Sectional Tromsø 7 Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-07)Introduction: The aim of this cross-sectional study was to explore the degree whereby dentists differentiate between repair versus replacement for failed restorations. A random selection of adult patients from North Norway was chosen from the larger Tromsø 7 study. <p> <p>Methods: A randomized sample of 3,653 persons (11.5% of the total number of individuals invited to the Tromsø 7 study, 51.5% ...