Viser treff 1-20 av 4971

    • Cortisol levels and cognitive profile in major depression: A comparison of currently and previously depressed patients 

      Høifødt, Ragnhild Sørensen; Waterloo, Knut; Wang, Catharina Elisabeth Arfwedson; Eisemann, Martin; Figenschau, Yngve Anton; Halvorsen, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-22)
      The association between depressive symptoms and elevated cortisol levels, and depression and cognitive functioning, has been less robust in outpatients with symptoms in the mild to moderate range. Furthermore, the association between elevated cortisol levels and cognitive functioning is unclear. In the present study, currently depressed (<i>n</i> = 37), previously depressed (<i>n</i> = 81) and never ...
    • Tobacco smoking and cessation and PDL1 inhibitors in non-small cell lung cancer (NSCLC): a review of the literature 

      Norum, Jan; Nieder, Carsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-02)
      <p><i>Background</i>: Programmed death ligand 1 (PD-L1) targeting immunotherapies, as pembrolizumab and nivolumab, have significantly improved outcome in patients with non-small cell lung cancer (NSCLC). Tobacco smoking is the number one risk factor for lung cancer and is linked to 80%–90% of these cancers. Smoking during cancer therapy may influence on radiotherapy and chemotherapy outcome. We aimed ...
    • Ultrasound-guided Sympathetic Block of the Radial Artery with Botulinum Toxin to Treat Vasospasm 

      Weum, Sven; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-12)
      Summary: Vasospastic disorders in the hand have been treated with surgical sympathectomy and recently with botulinum toxin A (BTX) injections in the palm. The purpose of this study was to evaluate if it is possible to obtain precise administration of BTX around the radial artery using a single ultrasound-guided injection. We present a novel technique using 1 single ultrasound-guided BTX injection ...
    • Stereotype threat-effects for Turkish-origin migrants in Germany: Taking stock of cumulative research evidence 

      Froehlich, Laura; Mok, Sog Yee; Martiny, Sarah E.; Deaux, Kay (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-24)
      Turkish-origin migrants on average show lower academic performance than Germans. This achievement gap cannot be fully explained by socio-economic differences between the groups. Negative competence stereotypes about Turkish-origin students predict the causal attributions that German preservice teachers make for migrants’ academic underperformance. Specifically, the more strongly preservice teachers ...
    • Subliminal priming og betinging av kunstige stereotyper 

      Brandt, Kai Erik (Master thesis; Mastergradsoppgave, 2018-11-09)
      En hyppig brukt metode for å studere subliminale fenomener er det maskerte primings-paradigmet. Tidligere studier med dette paradigmet har vist at subliminal priming og betinging har en effekt, men det er likevel uklarheter knyttet til ulike modererende faktorer. Slike modererende faktorer kan for eksempel være forsøksdeltakeres holdninger mot en stimulus eller det kan også være av mer teknisk art ...
    • Prevention of anxiety and depression in school children: Effectiveness of the transdiagnostic EMOTION program 

      Martinsen, Kristin Dagmar; Rasmussen, Lene-Mari Potulski; Wentzel-Larsen, Tore; Holen, Solveig; Sund, Anne Mari; Løvaas, Mona Elisabeth S; Patras, Joshua; Kendall, Philip C; Waaktaar, Trine; Neumer, Simon-Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      <i>Objective</i>: The objective of the study was to examine the effectiveness of a transdiagnostic program (EMOTION, Coping Kids Managing Anxiety and Depression) targeting symptoms of anxiety and depression in schoolchildren by comparing the intervention condition (EC) to a control condition (CC).<p> <p><i>Method</i>: A clustered randomized design was used with schools as the unit of randomization. ...
    • In search of a common currency: A comparison of seven EQ‐5D‐5L value sets 

      Olsen, Jan Abel; Lamu, Admassu Nadew; Cairns, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-24)
      The recently published EQ‐5D‐5L value sets from Canada, England, Japan, Korea, the Netherlands, Spain, and Uruguay are compared with an aim to identify any similarities in preference pattern. We identify some striking similarities for Canada, England, the Netherlands, and Spain in terms of (a) the relative importance of the 5 dimensions; (b) the relative utility decrements across the 5 levels; and ...
    • Teamwork in primary palliative care: general practitioners’ and specialised oncology nurses’ complementary competencies 

      Johansen, May-Lill; Ervik, Bente (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-21)
      <p><i>Background</i>: Generalists such as general practitioners and district nurses have been the main actors in community palliative care in Norway. Specialised oncology nurses with postgraduate palliative training are increasingly becoming involved. There is little research on their contribution. This study explores how general practitioners (GPs) and oncology nurses (ONs) experience their ...
    • Patterns of detectable viraemia among children and adults with HIV infection taking antiretroviral therapy in Zimbabwe 

      Sovershaeva, Evgeniya; Shamu, Tinei; Wilsgaard, Tom; Bandason, Tsitsi; Flægstad, Trond; Katzenstein, David; Ferrand, Rashida A.; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-31)
      <i>Objective</i>: To investigate the incidence and predictors of viraemia among individuals on antiretroviral therapy (ART) in Harare, Zimbabwe.<p> <p><i>Methods</i>: Children (0–19 years) and adults (>19 years) starting ART between 2013 and 2015 were followed for a median of 2.8 and 2.7 years, respectively. The incidence rates of virological failure (VF), low-level viraemia (LLV), and viral ...
    • Progesterone receptors in prostate cancer: Progesterone receptor B is the isoform associated with disease progression 

      Grindstad, Thea K.W.; Richardsen, Elin; Andersen, Sigve; Skjefstad, Kaja Konstanse; Rakaee, Mehrdad; Dønnem, Tom; Ness, Nora; Nordby, Yngve; Bremnes, Roy M.; Al-Saad, Samer; Busund, Lill-Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-27)
      The role of steroid hormones in carcinogenesis of the prostate is to some extent unraveled thorough the effect of androgen deprivation therapy on prostate cancer (PCa) progression. Other members of the steroid hormone family, such as progesterone, are also implicated in PCa, but progesterone’s role remains undefined. This study aimed to examine the distribution of progesterone receptor isoforms ...
    • The Role of Estrogen Receptor β (ERβ) in the Establishment of Hierarchical Social Relationships in Male Mice 

      Nakata, Mariko; Ågmo, Anders j; Satoshi, Shoko; Ogawa, Sonoko (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-22)
      Acquisition of social dominance is important for social species including mice, for preferential access to foods and mates. Male mice establish social rank through agonistic behaviors, which are regulated by gonadal steroid hormone, testosterone, as its original form and aromatized form. It is well known that estrogen receptors (ERs), particularly ER α (ERα), mediate effects of aromatized testosterone, ...
    • Making New Health Services Work: Nurse Leaders as Facilitators of Service Development in Rural Emergency Services 

      Hjertstrøm, Helle Kise; Obstfelder, Aud; Norbye, Bente (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-27)
      Nurse leaders in middle management positions in Norway and other Western countries perform additional new tasks due to high demands for quality and efficacy in healthcare services. These nurses are increasingly becoming responsible for service development and innovation in addition to their traditional leadership and management roles. This article analyses two Norwegian nurse leaders efforts in ...
    • Applying GRADE-CERQual to qualitative evidence synthesis findings–paper 7: understanding the potential impacts of dissemination bias 

      Booth, Andrew; Lewin, Simon Arnold; Glenton, Claire; Munthe-Kaas, Heather Menzies; Toews, Ingrid; Noyes, Jane; Rashidian, Arash; Berg, Rigmor; Nyakang’o, Brenda; Meerpohl, Jörg J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-25)
      <p><i>Background</i>: The GRADE-CERQual (Confidence in Evidence from Reviews of Qualitative research) approach has been developed by the GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group. The approach has been developed to support the use of findings from qualitative evidence syntheses in decision-making, including guideline development and policy formulation. ...
    • SYK Inhibition Potentiates the Effect of Chemotherapeutic Drugs on Neuroblastoma Cells in Vitro 

      Tümmler, Conny; Dumitriu, Gianina; Wickström, Malin; Coopman, Peter; Valkov, Andrey Yurjevich; Kogner, Per; Johnsen, John Inge; Moens, Ugo; Sveinbjørnsson, Baldur (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-10)
      Neuroblastoma is a malignancy arising from the developing sympathetic nervous system and the most common and deadly cancer of infancy. New therapies are needed to improve the prognosis for high-risk patients and to reduce toxicity and late effects. Spleen tyrosine kinase (SYK) has previously been identified as a promising drug target in various inflammatory diseases and cancers but has so far not ...
    • Isolated perfused working hearts provide valuable additional information during phenotypic assessment of the diabetic mouse heart 

      Pedersen, Tina Myhre; Boardman, Neoma; Hafstad, Anne Dragøy; Aasum, Ellen (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-01)
      Although murine models for studying the development of cardiac dysfunction in diabetes mellitus are well established, their reported cardiac phenotypes vary. These reported divergences may, in addition to the severity of different models, also be linked to the methods used for cardiac functional assessment. In the present study, we examined the functional changes using conventional transthoracic ...
    • Mesothelioma in Sweden: Dose–Response Analysis for Exposure to 29 Potential Occupational Carcinogenic Agents 

      Plato, Nils; Martinsen, Jan Ivar; Kjærheim, Kristina; Kyyrönen, Pentti; Sparen, Pär; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-21)
      <i>Background</i>: There is little information on the doseeresponse relationship between exposure to occupational carcinogenic agents and mesothelioma. This study aimed to investigate this association as well as the existence of agents other than asbestos that might cause mesothelioma.<p> <p><i>Methods</i>: The Swedish component of the Nordic Occupational Cancer (NOCCA) study consists of 6.78 ...
    • “Oh oobe doo, I wanna be like you” associations between physical activity of preschool staff and preschool children 

      Fossdal, Tom Stian; Kippe, Karin Oddbjørg; Handegård, Bjørn Helge; Lagestad, Pål Arild (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-29)
      <i>Objective</i>: Physical activity contributes to prevent serious diseases and ailments, and previous research indicates that lifestyle habits are likely to track from early childhood to adulthood. 90% of Norwegian children aged 1–5 are enrolled in preschools, and preschool staff can play an important role in children’s activity levels. This study’s aim was to identify whether any associations ...
    • Integrated framework of load monitoring by a combination of smartphone applications, wearables and point-of-care testing provides feedback that allows individual responsive adjustments to activities of daily living 

      Düking, Peter; Achtzehn, Silvia; Holmberg, Hans-Christer; Sperlich, Billy (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-19)
      Athletes schedule their training and recovery in periods, often utilizing a pre-defined strategy. To avoid underperformance and/or compromised health, the external load during training should take into account the individual’s physiological and perceptual responses. No single variable provides an adequate basis for planning, but continuous monitoring of a combination of several indicators of ...
    • Caring for the suicidal person: A Delphi study of what characterizes a recovery-oriented caring approach 

      Sellin, Linda; Kumlin, Tomas; Wallsten, Tuula; Wiklund Gustin, Lena (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-30)
      More research is needed for supporting mental health nurses in their caring for suicidal individuals. This study aimed to describe what characterizes a recovery‐oriented caring approach, and how this can be expressed through caring acts involving suicidal patients and their relatives. Delphi methodology was used, and research participants were recruited as experts by experience to explore a ...
    • High HIV and active tuberculosis prevalence and increased mortality risk in adults with symptoms of TB: a systematic review and meta-analyses 

      Nliwasa, Marriot; MacPherson, Peter; Gupta-Wright, Ankur; Mwapasa, Mphatso; Horton, Katherine; Odland, Jon Øyvind; Flach, Clare; Corbett, Elizabeth L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-31)
      <i>Introduction</i>: HIV and tuberculosis (TB) remain leading causes of preventable death in low- and middle-income countries(LMICs). The World Health Organization (WHO) recommends HIV testing for all individuals with TB symptoms, but implementation has been suboptimal. We conducted a systematic literature review and meta-analyses to estimate HIV and TB prevalence, and short-term (two to six months) ...