Now showing items 21-40 of 6131

    • Nucleic acids hybrids as advanced antibacterial nanocarriers 

      Obuobi, Sybil Akua Okyerewa; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-08)
      Conventional antibiotic therapy is often challenged by poor drug penetration/accumulation at infection sites and poses a significant burden to public health. Effective strategies to enhance the therapeutic efficacy of our existing arsenal include the use of nanoparticulate delivery platforms to improve drug targeting and minimize adverse effects. However, these nanocarriers are often challenged by ...
    • Silica Nanoparticles - A Versatile Tool for the Treatment of Bacterial Infections 

      Selvarajan, Vanitha; Obuobi, Sybil Akua Okyerewa; Rachel Ee, Pui Lai (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-15)
      The rapid emergence of drug resistance continues to outpace the development of new antibiotics in the treatment of infectious diseases. Conventional therapy is currently limited by drug access issues such as low intracellular drug accumulations, drug efflux by efflux pumps and/or enzymatic degradation. To improve access, targeted delivery using nanocarriers could provide the quantum leap in intracellular ...
    • Dekontaminering av pattedyrslakt ved bruk av damp eller varmt vann. Uttalelse fra Faggruppe for hygiene og smittestoffer i Vitenskapskomiteen for mattrygghet 

      Nesbakken, Truls; Christensen, Hardy; Skjerve, Eystein; Nygård, Karin Maria; Yazdankhah, Siamak Pour; Lunestad, Bjørn Tore; Kapperud, Georg; Lassen, Jørgen Fr; Robertson, Lucy; Olsvik, Ørjan; Tranulis, Michael A.; Tryland, Morten; Rimstad, Espen (Research report; Forskningsrapport, 2010-04-15)
      Mattilsynet har gitt VKM i oppgave å foreta en risikovurdering når det gjelder ”dekontaminering av pattedyrslakt ved bruk av varmt vann eller damp”. Da det er en bestemtdekontamineringsteknologi Mattilsynet ønsker utredet, velger faggruppen å bruke den mer presise betegnelsen ”overflatepasteurisering av slakt” som er i tråd med uttrykk og definisjoner som forskere innenfor dette området har benyttet ...
    • Miljørisikovurdering genmodifisert mais MON 89034 x NK603 fra Monsanto Company (EFSA/GMO/NL/2009/72). Uttalelse fra Faggruppe for genmodifiserte organismer Vitenskapskomiteen for mattrygghet 

      Sorteberg, Hilde-Gunn Opsahl; Bøhn, Thomas; Finne, Merethe Aasmo; Holck, Askild Lorentz; Klungland, Helge; Meadow, Richard; Myhr, Anne Ingeborg; Nerland, Audun Helge; Nes, Ingolf; Nielsen, Kaare Magne; Stabbetorp, Odd Egil; Vikse, Rose (Research report; Forskningsrapport, 2010-04-07)
      Helse- og miljørisikovurderingen av den insektresistente og herbicidtolerante maishybriden MON 89034 x NK603 (EFSA/GMO/NL/2009/72) fra Monsanto Company er utført av Faggruppe for genmodifiserte organismer i Vitenskapskomiteen for mattrygghet (VKM). VKM er bedt av Direktoratet for naturforvalting (DN) om å vurdere miljørisiko ved en eventuell godkjenning av maislinje MON 89034 x NK603 til dyrking og ...
    • Risk assessment of import and dissemination of intestinal pathogenic bacteria via fresh herbs and leafy vegetables from South-East Asia. Opinion of the Panel on Biological Hazards 

      Lassen, Jørgen Fredrik; Johannessen, Gro Skøien; Høiby, Ernst Arne; Kapperud, Georg; Lunestad, Bjørn Tore; Nesbakken, Truls; Nygård, Karin Maria; Olsvik, Ørjan; Robertson, Lucy Jane; Tranulis, Michael A.; Tryland, Morten; Rimstad, Espen (Research report; Forskningsrapport, 2008-06)
      Several studies have demonstrated that fresh herbs and green or leafy vegetables can be contaminated by intestinal pathogenic bacteria such as <i>Salmonella</i> spp. Although systematic surveys are probably not conducted in any countries some places, in recent years the Rapid Alert System for Food and Feed (RASFF) has received approximately 30 alerts annually on the detection of potentially pathogenic ...
    • Mestring i mottak og kommuner. Implementering og evaluering av Teaching Recovery Techniques i asylmottak, omsorgssentre og bosettingskommuner i Norge 

      Oppedal, Brit; Solhaug, Anne Kristine Nilsen; Friborg, Oddgeir; Biele, Guido (Research report; Forskningsrapport, 2019-03)
      Det er mangel på forskningsbaserte lavterskeltiltak som kan tilbys mange unge asylsøkere og flyktninger og avhjelpe traumerelaterte psykiske plager på relativt kort tid. Hensikten med denne rapporten er å informere om resultatene fra prosjektet Mestring i Mottak og Kommuner (MiMK), som evaluerte effekten av en lavterskelintervensjon for å redusere traumerelaterte psykiske plager blant asylsøkende ...
    • E-health in Norway Before and During the Initial Phase of the Covid-19 Pandemic 

      Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      The use of e-health services has for many years gradually increased in Norway as in most European countries. Searching for information about health and illness has previously by far been the most popular service. In this study, we review the literature with the aim of examining any changes in e-health use during the Covid-19 pandemic. We find that there has been a marked change in Norway, with an ...
    • Heat Development in the Pulp Chamber During Curing Process of Resin-Based Composite Using Multi-Wave LED Light Curing Unit 

      Nilsen, Bo Wold; Mouhat, Mathieu; Haukland, Torbjørn; Örtengren, Ulf Tore; Mercer, James B (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-08)
      <i>Objective</i>: The study aimed to investigate factors contributing to heat development during light curing of a flowable bulk-fill resin-based composite (SDR<sup>TM</sup>, Lot # 602000876, Dentsply Sirona, Konstanz, Germany) (RBC).<p><p> <i>Materials and Methods</i>: Temperatures were measured with calibrated thermocouples. A multi-wave light-emitting diode (LED) light curing unit (LCU) was ...
    • Following the fate of dye-containing liposomes in vitro 

      Cauzzo, Jennifer; Nystad, Mona; Holsæter, Ann Mari; Basnet, Purusotam; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-09)
      The rather limited success of translation from basic research to clinical application has been highlighted as a major issue in the nanomedicine field. To identify the factors influencing the applicability of nanosystems as drug carriers and potential nanomedicine, we focused on following their fate through fluorescence-based assays, namely flow cytometry and imaging. These methods are often used to ...
    • Current situation of paediatric chronic pain in Switzerland: prevalence and paediatricians’ experiences 

      Carlander, Maria (Master thesis; Mastergradsoppgave, 2019-07-10)
      Background: Chronic pain (CP) prevalence in children and adolescents has been increasing over the past decades. The patient-reported prevalence is around 25% depending on the methodology and location of pain. Chronic pain is defined in this study as persisting or recurrent pain that has lasted longer than three months. Objectives: To estimate the prevalence of chronic pain in children and adolescents ...
    • Managing chronic illnesses with remote patient monitoring in primary health care 

      Muller, Ashley Elizabeth; Ormstad, Sari Susanna; Jardim, Patricia; Johansen, Trine Bjerke; Berg, Rigmor (Research report; Forskningsrapport, 2020-03)
      Remote patient monitoring (RPM) allows for the real-time transmission of health data, evaluation of this data, and appropriate follow-up. This allows providers to monitor the health status of chronically ill patients and quickly adjust treatment regimes, without requiring that patients continually visit providers’ offices.<p><p> We summarized systematic reviews of a specific type of RPM that the ...
    • Teen mothers and the use of antenatal care services in Georgia 2017 – 2019: A cross-sectional study 

      Carter, Reed Andrew (Master thesis; Mastergradsoppgave, 2020-05-30)
      Teenage mothers are a particularly vulnerable population with a high risk of adverse health outcomes such as premature births and asphyxia compared to non-teen mothers. The Caucasus region historically has high rates of teenage pregnancies. The republic of Georgia is no exception therefore, this study aims to determine the utilization of ANC services of teens in order to ensure they are receiving ...
    • Hepatitis C virus screening attendance and its relation to age, education, geographic region and perinatal mortality - Georgian Birth Registry 2017/2018 

      Pajovic, Aleksandra (Master thesis; Mastergradsoppgave, 2020-05-28)
      Introduction: Hepatitis C virus (HCV) causes a liver disease hepatitis C, which can manifest in acute and chronic form, with potentially life-threatening complications. Globally, in 2017, there were approximately 115 million HCV infected people. Currently, screening for HCV during pregnancy is offered to all pregnant women in a very few countries in the world. Importance of screening every pregnant ...
    • Empirical prescribing of penicillin G/V reduces risk of readmission of hospitalized patients with community-acquired pneumonia in Norway: a retrospective observational study 

      Høgli, June Utnes; Garcia, Beate Hennie; Svendsen, Kristian; Skogen, Vegard; Småbrekke, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-15)
      <i>Background</i> - Norwegian guideline recommendations on first-line empirical antibiotic prescribing in hospitalised patients with community-acquired pneumonia (CAP) are penicillin G/V in monotherapy, or penicillin G in combination with gentamicin (or cefotaxime) in severely ill patients. The aim of this study was to explore how different empirical antibiotic treatments impact on length of hospital ...
    • Privacy-preserving architecture for providing feedback to clinicians on their clinical performance 

      Yigzaw, Kassaye Yitbarek; Budrionis, Andrius; Ruiz, Luis Marco; Henriksen, Torje Dahle; Halvorsen, Peder Andreas; Bellika, Johan Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-22)
      <i>Background</i> - Learning from routine healthcare data is important for the improvement of the quality of care. Providing feedback on clinicians’ performance in comparison to their peers has been shown to be more efficient for quality improvements. However, the current methods for providing feedback do not fully address the privacy concerns of stakeholders.<p><p> <i>Methods</i> - The paper ...
    • Shoulder and neck pain in female office employees in Tromsø 

      Shrestha, Rejina (Master thesis; Mastergradsoppgave, 2018-07-04)
      Objective- To determine the prevalence and predictors of neck and shoulder pain in female office workers in Tromsø. Methods- A cross-sectional study was performed using population- based data from the Tromsø 6 study which was carried out between 2007 and 2008. The population under study were 619 female office workers. Information regarding individual factors, lifestyle factors and work factors ...
    • Efficacy of Intravenous, Endotracheal, or Nasal Adrenaline Administration During Resuscitation of Near-Term Asphyxiated Lambs 

      Songstad, Nils Thomas; Klingenberg, Claus; McGillick, Erin V.; Polglase, Graeme R.; Zahra, Valerie; Schmölzer, Georg M.; Davis, Peter G.; Hooper, Stuart B.; Crossley, Kelly J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-02)
      <i>Objectives</i>: Neonatal resuscitation guidelines recommend administering intravenous (IV) adrenaline if bradycardia persists despite adequate ventilation and chest compressions (CC). Rapid IV access is challenging, but little evidence exists for other routes of administration. We compared IV, endotracheal (ET), and intranasal routes for adrenaline administration during resuscitation of asphyxiated ...
    • A Probabilistic Bag-to-Class Approach to Multiple-Instance Learning 

      Møllersen, Kajsa; Hardeberg, Jon Yngve; Godtliebsen, Fred (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)
      Multi-instance (MI) learning is a branch of machine learning, where each object (bag) consists of multiple feature vectors (instances)—for example, an image consisting of multiple patches and their corresponding feature vectors. In MI classification, each bag in the training set has a class label, but the instances are unlabeled. The instances are most commonly regarded as a set of points in a ...
    • The Northern Norway mother-and-child contaminant cohort study: implementation, population characteristics and summary of dietary findings 

      Veyhe, Anna Sofia; Hansen, Solrunn; Sandanger, Torkjel Manning; Nieboer, Evert; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-28)
      <p><i>Objectives.</i> To describe the essential features of a new Northern Norway mother-and-child contaminant cohort study called MISA, including its rationale, content, implementation and selected findings (mostly dietary). <p><i>Study design. </i>Cross-sectional with longitudinal aspects. <p><i>Methods.</i> Five hundred and fifteen eligible women were enrolled in early pregnancy, with 391 ...
    • Endothelial function after pancreas transplantation - A single-center observational study 

      Nordheim, Espen; Dahle, Dag Olav; Strøm Halden, Thea Anine; Birkeland, Kåre I.; Åsberg, Anders; Hartmann, Anders; Horneland, Rune; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)
      <i>Background</i> - Patients with diabetes mellitus treated with successful pancreas transplantation (PTX) normalize hyperglycemia, but are exposed to immunosuppressive drugs that may impair endothelial function. This study aimed to evaluate endothelial function in single PTX recipients.<p><p> <i>Methods</i> - Flow‐mediated dilatation (FMD) in the brachial artery was measured by ultrasound 8 weeks ...