Nye registreringer

  • Patient-reported symptoms before adjuvant locoregional radiotherapy for breast cancer: triple-negative histology impacts the symptom burden 

    Nieder, Carsten; Johnsen, Silje Kristine; Winther, Annette M.; Mannsåker, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-26)
    Background Multimodal breast cancer treatment may cause side effects reflected in patient-reported outcomes and/or symptom scores at the time of treatment planning for adjuvant radiotherapy. In our department, all patients have been assessed with the Edmonton Symptom Assessment System (ESAS; a questionnaire addressing 11 major symptoms and wellbeing on a numeric scale of 0–10) at the time of ...
  • Global trends of acupuncture clinical research on analgesia from 2010 to 2023: a bibliometric and visualization analysis 

    Li, Zhi-Qiang; Wang, Xue-Feng; Feng, Cao; Fei, Yu-Tong; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-11)
    Objective: Acupuncture, acknowledged as a potent non-pharmacological therapy, is frequently employed to alleviate pain. Despite its widespread use, there has been a lack of overarching bibliometric analysis of clinical research on acupuncture analgesia. We aimed to summarize current patterns, hotspots, and development trends in this field through bibliometric analysis.<p> <p>Methods: This study ...
  • Socioeconomic status and self-regard income predicts self-respect over time 

    Renger, Daniela; Lohmann, Julian F.; Renger, Sophus; Martiny, Sarah E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-14)
    Past research has shown that the socioeconomic status (e.g., income or education) is associated with people’s self-evaluation, such as global self-esteem. In the present research, we argue that socioeconomic status also affects people’s belief of possessing the same rights as others (i.e., self-respect). In a cross-sectional study (N = 298) and a longitudinal study (N = 379), we investigated the ...
  • Effect of a low-carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial 

    Lundanes, Julianne; Sandnes, Frida Huhta; Gjeilo, Kari Hanne; Salater, Sissel; Alho Letra Martins, Catia Patricia; Nymo, Siren; Hanson, Patrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-16)
    Objective: The primary objective of this study was to evaluate the effect of a low-carbohydrate diet (LCD) compared with a control diet on pain in female patients with lipedema. The secondary objectives were to compare the impact of the two diets on quality of life (QoL) and investigate potential associations of changes in pain with changes in body weight, body composition, and ketosis.<p> <p>Methods: ...
  • Legacy and alternative per- and polyfluoroalkyl substances (PFAS) alter the lipid profile of HepaRG cells 

    Kashobwe, Lackson; Sadrabadi, Faezeh; Brunken, Lars; Miranda Fernandes Coelho, Ana Carolina; Sandanger, Torkjel Manning; Braeuning, Albert; Buhrke, Thorsten; Öberg, Mattias; Hamers, Timo; Leonards, Pim.E.G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-10)
    Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals used in various industrial and consumer products. They have gained attention due to their ubiquitous occurrence in the environment and potential for adverse effects on human health, often linked to immune suppression, hepatotoxicity, and altered cholesterol metabolism. This study aimed to explore the impact of ten individual PFAS, ...
  • Reliability and validity of the Personality Disorder Severity ICD-11 (PDS-ICD-11) scale and the Revised Personality Assessment Questionnaire for ICD-11 (PAQ-11R) in a Norwegian community sample 

    Lorentzen, Hanna Sirnes; Bårdsen, Pauline Marie; Thimm, Jens (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-25)
    In the ICD-11, a new model for the diagnosis of personality disorders is included, consisting of an assessment of the severity of personality impairment as well as an optional evaluation of pathological personality traits. This study aimed to examine the reliability, structural validity, and convergent and discriminant validity of the Norwegian versions of the Personality Disorder Severity ICD-11 ...
  • Risk and prevalence of Relative Energy Deficiency in Sport (REDs) among professional female football players 

    Dasa, Marcus Småvik; Friborg, Oddgeir; Kristoffersen, Morten; Pettersen, Gunn; Sagen, Jørn Vegard; Torstveit, Monica Klungland; Sundgot-Borgen, Jorunn; Rosenvinge, Jan Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-29)
    A high prevalence of low energy availability (LEA) has been reported in female football players. This is of concern as problematic LEA may evolve into a syndromic pattern known as relative energy deficiency in sport (REDs). Given the difficulties in accurately assessing LEA, our study shifts emphasis to measurable indicators of REDs, serving as proxies for health detriments caused by LEA. The ...
  • Study approaches mediate associations between learning environment and academic performance 

    Bonsaksen, Tore; Tannoubi, Amayra; Gramstad, Astrid; Stigen, Linda; Carstensen, Tove; Mørk, Gry (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-02)
    Background: While study approaches have been directly associated with students’ academic performance, learning environment factors may play a more indirect role. The aim of this study was (i) to assess learning environment factors as predictors of students’ average exam grades, and (ii) whether study approaches mediated associations between learning environment factors and exam grades.<p> <p>Methods: ...
  • Profile of per- and polyfluoroalkyl substances, source appointment, and determinants in Argentinean postpartum women 

    Hansen, Solrunn; Xu, Shanshan; Huber, Sandra; Alvarez, Marisa Viviana; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-13)
    Background: Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals with potential adverse health effects. Information concerning PFAS concentrations in relation to pregnancy is scarce in South America and non-existent in Argentina. Aim: We aimed to investigate an extended maternal PFAS profile herein serum concentrations in a regional and global view, source appointment, ...
  • Medical trainees’ speciality considerations at their transition from under- to postgraduate education: a descriptive, cross-sectional study 

    Gjessing, Sofie; Risør, Torsten; Kristensen, Jette Kolding (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-03)
    Purpose: This paper aims to provide knowledge on medical trainees’ considerations about specialisation as they move from undergraduate to postgraduate medical education; especially their interest in general practice compared to other specialities.<p> <p>Method: We developed and content-validated a questionnaire to examine medical trainees’ speciality considerations and conducted a descriptive, ...
  • Tumor versus Tumor Cell Targeting in Metal-Based Nanoparticles for Cancer Theranostics 

    Urbano-Gámez, Jesús David; Guzzi, Cinzia; Bernal, Manuel; Solivera, Juan; Martinez, Inigo Zubiavrre; Caro, Carlos; García-Martín, María Luisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-10)
    The application of metal-based nanoparticles (mNPs) in cancer therapy and diagnostics (theranostics) has been a hot research topic since the early days of nanotechnology, becoming even more relevant in recent years. However, the clinical translation of this technology has been notably poor, with one of the main reasons being a lack of understanding of the disease and conceptual errors in the design ...
  • Applicability and Psychometric Properties of General Mental Health Assessment Tools in Autistic People: A Systematic Review 

    Halvorsen, Marianne Berg; Kildahl, Arvid Nikolai; Kaiser, Sabine; Axelsdottir, Brynhildur; Aman, Michael G.; Helverschou, Aud Sissel Berge (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-13)
    In recent years, there has been a proliferation of instruments for assessing mental health (MH) among autistic people. This study aimed to review the psychometric properties of broadband instruments used to assess MH problems among autistic people. In accordance with the PRISMA guidelines (PROSPERO: CRD42022316571) we searched the APA PsycINFO via Ovid, Ovid MEDLINE, Ovid Embase and the Web of Science ...
  • Free Vascularized Fibula Graft as Primary Salvage Procedure for Acute Cervical Osteomyelitis Caused by Epidural Abscess 

    Ciosek, Timothy Allan; Sørlie, Andreas; Munch-Ellingsen, Jens; Solberg, Tore; Weum, Sven Magne; Weerd, Louis de (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-24)
    Acute cervical osteomyelitis due to an epidural abscess and pyogenic spondylodiscitis in an immunosuppressed patient with progressive myelopathy is a challenge for the reconstructive surgeon. This report presents our novel approach to treat such a condition in a 56-year-old patient in whom antibiotic treatment and decompression of the medulla by laminectomy of C4–C6 failed. Under general anesthesia, ...
  • Oral nanotherapeutic formulation of insulin with reduced episodes of hypoglycaemia 

    Hunt, Nicholas J; Lockwood, Glen P; Heffernan, Scott; Daymond, Jarryd; Ngu, Meng; Narayanan, Ramesh; Westwood, Lara; Mohanty, Biswaranjan; Esser, Lars; Williams, Charlotte; Kuncic, Zdenka; Mccourt, Peter Anthony Gerard; Le Couteur, David; Cogger, Victoria Carroll (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-02)
    Injectable insulin is an extensively used medication with potential life-threatening hypoglycaemic events. Here we report on insulin-conjugated silver sulfide quantum dots coated with a chitosan/glucose polymer to produce a responsive oral insulin nanoformulation. This formulation is pH responsive, is insoluble in acidic environments and shows increased absorption in human duodenum explants and ...
  • Post-Conization HPV Vaccination and Its Impact on Viral Status: A Retrospective Cohort Study in Troms and Finnmark, 2022 

    Rykkelid, Marie; Wennberg, Helga Marie; Richardsen, Elin Helmine; Sørbye, Sveinung (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-02)
    Human papillomavirus (HPV) is associated with cellular changes in the cervix leading to cancer, which highlights the importance of vaccination in preventing HPV infections and subsequent cellular changes. Women undergoing the loop electrosurgical excision procedure (LEEP), a treatment for high-grade cervical intraepithelial neoplasia (CIN2+), remain at risk of recurrence. This study assessed the ...
  • The prognostic importance of traumatic axonal injury on early MRI: the Trondheim TAI-MRI grading and quantitative models 

    Moen, Kent Gøran; Flusund, Anne-Mari Holte; Moe, Hans Kristian; Andelic, Nada; Skandsen, Toril; Håberg, Asta; Kvistad, Kjell Arne; Olsen, Øystein E.; Saksvoll, Elin Hildrum; Abel-Grüner, Sebastian; Anke, Audny Gabriele Wagner; Follestad, Turid; Vik, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-19)
    Objectives We analysed magnetic resonance imaging (MRI) findings after traumatic brain injury (TBI) aiming to improve the grading of traumatic axonal injury (TAI) to better reflect the outcome.<p> <p>Methods Four-hundred sixty-three patients (8–70 years) with mild (n = 158), moderate (n = 129), or severe (n = 176) TBI and early MRI were prospectively included. TAI presence, numbers, and volumes ...
  • Critical care nurses' competence in mentoring students in intensive care units—A cross-sectional study 

    Rasi, Matias; Hanssen, Tove Aminda; Norbye, Bente; Mikkonen, Kristina; Kvande, Monica Evelyn (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-26)
    Background: Mentors play an important role in the practical education of critical care nursing students in intensive care units, yet little is known about the mentoring competencies of critical care nurses. Aim: The aim of this study was to assess Norwegian critical care nurses’ competence in mentoring students in intensive care units.<p> <p>Design: This study has a descriptive, cross-sectional ...
  • Dose-Response Effects of MittEcho, a Measurement Feedback System, in an Indicated Mental Health Intervention for Children in Municipal and School Services in Norway 

    Haug, Ida Mari; Neumer, Simon-Peter; Handegård, Bjørn Helge; Lisøy, Carina; Rasmussen, Lene-Mari Potulski; Bania, Elisabeth Valmyr; Adolfsen, Frode; Patras, Joshua Steven (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-29)
    Including routine client feedback can increase the effectiveness of mental health interventions for children, especially when implemented as intended. Rate of implementation, or dose, of such feedback interventions has been shown to moderate results in some studies. Variation in implementation and use of client feedback may also contribute to the mixed results observed within the feedback ...
  • Status epilepticus in POLG disease: a large multinational study 

    Hikmat, Omar; Naess, Karin; Engvall, Martin; Klingenberg, Claus Andreas; Rasmussen, Magnhild; Brodtkorb, Eylert; Ostergaard, Elsebet; de Coo, Irenaeus; Pias-Peleteiro, Leticia; Isohanni, Pirjo; Uusimaa, Johanna; Majamaa, Kari; Kärppä, Mikko; Ortigoza-Escobar, Juan Dario; Tangeraas, Trine; Berland, Siren; Harrison, Emma; Biggs, Heather; Horvath, Rita; Darin, Niklas; Rahman, Shamima; Bindoff, Laurence Albert (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-01)
    We aimed to provide a detailed phenotypic description of status epilepticus (SE) in a large cohort of patients with POLG disease and identify prognostic biomarkers to improve the management of this life-threatening condition. In a multinational, retrospective study with data on patients with POLG disease from seven European countries, we identified those who had SE. The age of SE onset, accompanying ...
  • TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery 

    Saha, Bhaskar; Olsvik, Hallvard Lauritz; Williams, Geneva L.; Oh, Seeun; Evjen, Gry; Sjøttem, Eva Synnøve; Mandell, Michael A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-29)
    Ubiquitination of mitochondrial proteins provides a basis for the downstream recruitment of mitophagy machinery, yet whether ubiquitination of the machinery itself contributes to mitophagy is unknown. Here, we show that K63-linked polyubiquitination of the key mitophagy regulator TBK1 is essential for its mitophagy functions. This modification is catalyzed by the ubiquitin ligase TRIM5a and is ...

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