Recent additions

  • Role of the Complement System in the Pathogenesis of Venous Thromboembolism 

    Høiland, Ina Isabella (Doctoral thesis; Doktorgradsavhandling, 2019-04-02)
    Venous thromboembolism (VTE) is a common disease with serious short- and long-term complications. VTE is a collective term for deep vein thrombosis (DVT) and pulmonary embolism (PE) and is the third most common cardiovascular disease, causing significant morbidity and mortality. Despite preventive strategies, the incidence of VTE has been stable or increasing slightly during the last decades, affecting ...
  • Expression and functional properties of selected miRNAs in human cancer tissue and cancer cell lines 

    Johannessen, Charles Walquist (Doctoral thesis; Doktorgradsavhandling, 2019-03-01)
    MicroRNAs (miRNAs) are small non-coding RNAs (ncRNAs) involved in the regulation of gene expression, and they are often seen dysregulated in cancer. For this reason, it is of great scientific interest to study these ncRNAs to better understand their distribution in human tissues and their mode of function. Based on a comprehensive miRNA microarray from 108 breast cancers in the Norwegian Woman and ...
  • In Home we trust. An ethnographic study of mental health and the use of traditional medicine in a North Norwegian community 

    Kiil, Mona Anita (Doctoral thesis; Doktorgradsavhandling, 2019-05-24)
    Traditional healing practices used when faced with illness or crisis, exist in many North Norwegian communities. Northern Troms has a historical multi-ethnicity of Sami, Kven and Norwegian. The notion of culture appears ambivalent and ambiguous, particularly concerning the Sami identity, but cultural diversity is nevertheless manifested through the use of traditional healing practices such as reading. ...
  • ‘Will I get cancer again?’ An ethnography of worries, healing landscapes and sensation-to-symptom processes among people living in the aftermath of cancer in rural Norway 

    Skowronski, Magdalena (Doctoral thesis; Doktorgradsavhandling, 2019-04-29)
    <p>Today, 71% of those who are diagnosed with cancer live five years or longer after treatment. Although the level of mortality varies considerably between different cancer diagnoses, the total number of people who recover after cancer is increasing. There is a need to gain knowledge on how people who live in the aftermath of cancer treatment experience health and illness, bodily sensations, everyday ...
  • Oral health in Russian young adults: A study on determinants of dental health, dental anxiety, and oral health-related quality of life in medical and dental students in North-West Russia 

    Drachev, Sergei N. (Doctoral thesis; Doktorgradsavhandling, 2019-03-29)
    <p><i>Background:</i> Dental caries and periodontal diseases are the most common oral diseases, affecting millions of people worldwide. These diseases are highly preventable; therefore any measures that promote oral health (OH) should be implemented at the community and individual level. Although programmes designed to prevent OH problems often focus on children, young adults aged 18-25 years are ...
  • Immune Infiltration and Clinical Outcome in Non-Small Cell Lung Cancer 

    Rakaee, Mehrdad (Doctoral thesis; Doktorgradsavhandling, 2019-03-12)
    Lung cancer is the cancer responsible for the most deaths worldwide. Treatment is multimodal and based on information specific to the tumor (histology, stage, biology and genetics aberrations) and patient-related factors. During the last decade, the arrival of novel targeted therapies and immunotherapy, has led to a paradigm shift in the management of lung cancer. In this regard, assessment of tumor ...
  • Epidemiology of cervical cancer and high risk of HPV infection with a focus on Arkhangelsk City and County, Northwest Russia 

    Roik, Elena Evgenievna (Doctoral thesis; Doktorgradsavhandling, 2019-01-25)
    Human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide. It is also known as important risk factor for cervical cancer. Generally speaking, finding any cancer at an early stage is often believed to be the most important factor for longer survival. However, age at diagnosis, residence (i.e., accessibility to health care) and cell type of the tumor (less or ...
  • Cognitive function and mild cognitive impairment in a general population: roles of cardiovascular and genetic risk factors and magnetic resonance volumetry. The Tromsø Study 

    Rogne, Sigbjørn Olav (Doctoral thesis; Doktorgradsavhandling, 2018-12-14)
    Alzheimers sykdom er den vanligste årsaken til demens, dernest karsykdom som forårsaker vaskulær demens. De fleste som får Alzheimers demens etter 65 års alder (late onset Alzheimer’s Disease, LOAD), har ikke sykdommen i familien fra tidligere. Men opptil 25 % av dem som får LOAD, har biologiske slektninger med LOAD. Personer i familier med opphopning av LOAD, har økt risiko for å få LOAD. Det er ...
  • Overweight/obesity, body composition and bone mass in late adolescence: the relation with birth weight, childhood body mass index and growth. The Tromsø Study: Fit Futures, a longitudinal cohort study 

    Evensen, Elin Kristin (Doctoral thesis; Doktorgradsavhandling, 2019-02-07)
    <i>Background and aim</i>: High prevalence of childhood overweight/obesity is a major health concern due to related immediate and long-term health problems. Early identification of children at risk is of interest, as preventing or delaying the onset of obesity may influence future health. The aim of this thesis was to study how early life factors such as birth weight, childhood body mass index (BMI, ...
  • Three essays on measuring health-related quality of life: external and internal relationships of the EQ-5D-5L 

    Gamst-Klaussen, Thor (Doctoral thesis; Doktorgradsavhandling, 2019-01-18)
    The use of quality-adjusted life years (QALYs) as a commensurable health outcome measure has been encouraged by health authorities in many countries in order to aid decisions on healthcare priorities. A key methodological challenge is to estimate the weights used for valuing health-related quality of life, i.e. the “Q” in QALY, based on people’s preferences. Such generic preference-based measures ...
  • Systems Epidemiology Approach in Endometrial Cancer. The NOWAC Study 

    Gavrilyuk, Oxana (Doctoral thesis; Doktorgradsavhandling, 2018-12-12)
    Endometrial cancer (EC) is one of the most common gynecologic cancers with extensively rising incidence worldwide. Norway is among the countries with the highest rates of EC. Although, most of the established risk factors for EC are well described, there are few studies from Norway investigating them in a cohort design. Moreover, modern clinical medicine, especially oncology, is moving towards ...
  • Hearing in rock musicians 

    Størmer, Carl Christian Lein (Doctoral thesis; Doktorgradsavhandling, 2018-12-14)
    Musicians are known to have an increased prevalence of hearing loss and tinnitus due to noise-induced cochlear damage. Rock music is popularly considered a major culprit in terms of excessive sound levels, but the literature on hearing in rock musicians is sparse. In this dissertation the hearing levels of a large number of rock musicians are assessed in relation to factors such as degree of exposure, ...
  • Arterial cardiovascular diseases and risk of venous thromboembolism 

    Rinde, Ludvig Balteskard (Doctoral thesis; Doktorgradsavhandling, 2018-12-12)
    Despite differences in epidemiology, pathology, and treatment, growing evidence suggests a bidirectional relationship between venous thromboembolism (VTE), a collective term for pulmonary embolism (PE) and deep vein thrombosis (DVT), and arterial cardiovascular diseases (CVD, i.e., myocardial infarction [MI] and ischemic stroke). The aim of this thesis was to investigate the impact of atherosclerosis, ...
  • Family and community involvement in Indigenous social work. A comparative study 

    Nygård, Reidunn Håøy (Doctoral thesis; Doktorgradsavhandling, 2018-12-07)
    This thesis investigates the relevance of family and community involvement for culturally adequate social work in Indigenous communities. The study is qualitative and comparative. I compare social work within Indigenous communities in Norway and Montana with the aim of adding to the available knowledge regarding culturally adequate social work in these communities. The thesis consists of three ...
  • The hemodynamic aspects of pharmacological manipulation of cardiac contractility and vascular resistance in rewarming from hypothermia 

    Håheim, Brage (Doctoral thesis; Doktorgradsavhandling, 2018-12-07)
    <p><i>Paper I</i> <br>To describe hemodynamic response and phosphorylation of cardiac troponin I during rewarming from deep, stable hypothermia with use of the calcium sensitizer and PDE3 inhibitor levosimendan, compared to animals given placebo. <p> <p><i>Paper II</i> <br>To describe hemodynamic response to lowered systemic vascular resistance by nitroprusside administration during rewarming ...
  • Studies in pathways to care - duration of untreated psychosis and its determining factors in early psychosis 

    Kvig, Erling Inge (Doctoral thesis; Doktorgradsavhandling, 2018-11-23)
    Mange pasienter med en førstegangspsykose får behandling sent i forløpet og har en lang varighet av ubehandlet psykose (VUP). Forsinket behandling kan skyldes både indre (lidelse og pasient relaterte) og ytre (tjeneste og systemrelaterte) faktorer. Til tross for at nyere forskning har dokumentert at en stor del av forsinkelsen skjer mens pasienten mottar behandling i spesialisthelsetjenesten, så er ...
  • Sex differences in pain, fear of pain and placebo analgesia 

    Vambheim, Sara Magelssen (Doctoral thesis; Doktorgradsavhandling, 2018-11-13)
    The hypothesis that males are more responsive to placebo treatment than females was tested experimentally in this thesis. The hypothesis was confirmed and the results showed that the sex difference was related to a difference in males’ and females’ stress response after placebo treatment. Placebo responses on pain unpleasantness and the P2 component was found in males, but not in females. The ...
  • Self-regulating Physical and Mental Activities: Intensive Longitudinal Intervention Studies of Physical Fitness and Happiness 

    Thorsteinsen, Kjærsti (Doctoral thesis; Doktorgradsavhandling, 2018-11-29)
    Being active is a primary necessity in life, but it is also an essential part of what makes life worth living. This thesis explored goal pursuit activities people might not experience as pleasant in the moment, but where the self-chosen activities are still considered good and worthwhile. We hypothesized that online self-regulation interventions would be effective in increasing effortful physical ...
  • Biology of mesenchymal stromal cells: Chondrogenesis, paracrine signalling and cartilage repair 

    Islam, Md Ashraful (Doctoral thesis; Doktorgradsavhandling, 2018-10-12)
    The management of articular cartilage lesions is one of the weighty challenges for orthopaedic surgeons. The use of mesenchymal stem/stromal cells (MSCs) has demonstrated as an alternative cell source for cartilage repair due to their multilineage differentiation potential and hypoimmunogenic properties. Despite the advances in cartilage repair techniques, there is no consensus relating to the most ...
  • Coffee and cancer 

    Lukic, Marko (Doctoral thesis; Doktorgradsavhandling, 2018-10-12)
    <p>You cannot imagine powering through the day without your favorite beverage being on your desk all the time. Have you ever wondered what the consequences might be? </p> <p>It seems that even before you have opened your eyes, there’s already a kettle on the stove or the coffee machine is purring. On the way to work, you have another cup to go from the nearby coffee chop. Long meetings demand ...

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