Now showing items 1-20 of 444

    • Academic performance and student dropout. Results from two studies in upper secondary and higher education in Northern Norway 

      Sæle, Rannveig Grøm (Doctoral thesis; Doktorgradsavhandling, 2016-08-19)
      Education is important for the individual and for society. One of the most important and stable predictors of educational dropout is academic performance, typically measured by grades. This thesis aims to investigate factors related to academic performance and student dropout. It comprises two projects. The first project, Young Will (Ung vilje), is based on a sample of adolescents entering upper ...
    • Active Placebo - The relation of treatment expectancies to active analgesic treatments 

      Bjørkedal, Espen (Doctoral thesis; Doktorgradsavhandling, 2016-11-25)
      The placebo analgesic effect refers to the improvement in a group receiving an inert treatment compared to a group receiving no treatment. Conversely, nocebo hyperalgesia refers to the worsening in a group receiving an inert treatment compared to a no treatment control group. The hypothesis that active treatments, e.g. a drug, enhance the placebo effect has received some support but rarely been ...
    • Activity related pain in patients with musculoskeletal disorders : an explorative study 

      Damsgård, Elin (Doctoral thesis; Doktorgradsavhandling, 2010-02-26)
      Chronic musculoskeletal pain is a common health problem and a major cause for disability pension in Norway. Increased pain and fear related to general activity and exercise may be a barrier to rehabilitation of patients with chronic muscular-skeletal disorders. <br>The aim of the present research was to investigate the occurrence of activity related pain, and to explore its association with fear, ...
    • The ACUFLASH study. Acupuncture treatment for postmenopausal hot flashes : can traditional Chinese acupuncture in addition to self-care reduce hot flash frequency and intensity, compared with self-care alone? 

      Borud, Einar Kristian (Doctoral thesis; Doktorgradsavhandling, 2010-04-16)
      Introduction. Hot flashes and night sweats are the most prevalent symptoms in menopause. Hormone therapy with oestrogen is considered the most effective treatment. However, recent research show that long term use of oestrogen increases the risk of serious adverse effects, and women and their health care providers are looking for alternatives. Acupuncture is one of the most frequently used complementary ...
    • Acupuncture for postoperative morbidities in children, and placebo by proxy 

      Liodden, Ingrid (Doctoral thesis; Doktorgradsavhandling, 2016-04-29)
      Acupuncture may be beneficial for the prevention of postoperative nausea and vomiting in children and is associated with minor adverse events. The two RCTs in this dissertation investigated the effects of acupuncture by means of a pragmatic randomised controlled trial design. Placebo effects are affected by patient expectancy towards the treatment. The present survey explored the placebo effects ...
    • Acute heart failure syndromes : treatment, outcomes and pathophysiological aspects of inflammation and vascular function 

      Hermansen, Stig Eggen (Doctoral thesis; Doktorgradsavhandling, 2012-11-01)
      Akutt hjertesvikt, spesielt ved sirkulatorisk kollaps, er en dramatisk tilstand med høy dødelighet. Forekomsten av akutt hjertesvikt er økende og tilgjengelig kunnskap om sykdomsmekanismene samt medisinsk behandling er begrenset.De siste tiår har det vært en revolusjonerende utvikling i behandlingen av og overlevelsen ved iskemisk hjertesykdom og akutt hjerteinfarkt. Tilsvarende utvikling har det ...
    • Adolescents and self-harm. A study of factors associated with suicide and use of health care services following self-harm in national representative populations of Norwegian adolescents 

      Fadum, Elin Anita (Doctoral thesis; Doktorgradsavhandling, 2017-01-11)
      This thesis uses data recorded in Norwegian governmental health registers, as well as data collected in a nationwide school survey carried out in Norway, to study risk factors for suicide and factors associated with the use of health services following self-harm in adolescents. Paper I examined suicide in a population of half a million men with physician-diagnosed minor or major mental health ...
    • Adolescents´ lifestyle and bone health. The Tromsø Study, Fit Futures 

      Winther, Anne (Doctoral thesis; Doktorgradsavhandling, 2015-12-16)
      Med data fra folkehelseundersøkelsen Fit Futures har vi sammenlignet norske ungdommers beintetthet med internasjonale referanseverdier og undersøkt sammenhengen mellom livsstilsfaktorer og beintetthet. Til tross for at Norges eldre er på verdenstoppen når det gjelder beinskjørhet (osteoporose) og beinbrudd, har dagens ungdommer like høy eller høyere beintetthet som jevngamle ungdommer i Europa ...
    • Advanced flow cytometry to study signaling pathways and predict outcome in B cell malignancies 

      Blix, Egil Støre (Doctoral thesis; Doktorgradsavhandling, 2015-01-16)
    • Advanced Non-small Cell Lung Cancer Effects of Chemotherapy and Impact on Health Related Quality of Life 

      Helbekkmo, Nina (Doctoral thesis; Doktorgradsavhandling, 2009-03-13)
      Avhandlingen presenterer behandlingseffekt, bivirkninger og livskvalitet hos lungekreftpasienter som får moderne cellegiftbehandling. Pasientene med performance status (PS) 2 er etterpå vurdert separat. <br><br>Avhandlingens tittel er ”Advanced non-small cell Lung Cancer – Effects of Chemotherapy and Impact on Health Related Quality of Life”. Den ble forsvart for graden PhD 13.03.2009. På verdensbasis ...
    • Age-related macular degeneration: Prevalence and risk factors - a cross-sectional study : The Tromsø Study 2007/2008 

      Erke, Maja Gran (Doctoral thesis; Doktorgradsavhandling, 2013-05-30)
      Age-related macular degeneration (AMD) is an important cause of visual impairment and blindness worldwide. The number of people affected by the disease is expected to rise due to increasing longevity. Development of adequate eye care for these patients should be based on knowledge about the prevalence of AMD. Further, preventive measures are the best strategy for any disease. The aims of this ...
    • Alcohol prevention among adolescents - A study on determinants and parental influence 

      Adolfsen, Frode (Doctoral thesis; Doktorgradsavhandling, 2018-03-09)
      The main goal of this thesis was to evaluate the effectiveness of an alcohol prevention program both for parents and adolescents in Norway.The aim of the first study was to estimate the prevalence of alcohol drinking among Norwegian adolescents, as well as to identify determinants associated with early onset of drinking and test models for predicting early onset. The study showed that approximately ...
    • Allosteric modulation of GABAergic and glutamatergic metabotropic receptors 

      Freyd, Thibaud (Doctoral thesis; Doktorgradsavhandling, 2018-09-10)
      G-protein coupled receptors (GPCRs) are targets for 1/3 of the drugs available on the market making research on this class of proteins a very hot topic in the field of drug discovery. γ-amino butyric acid (GABA) and glutamate are respectively the main inhibitory and the main excitatory neurotransmitters in the mammalian central nervous system (CNS). The GABAB receptor (GABAB-R) and the metabotropic ...
    • Alterations in the renal microenvironment during the development of lupus nephritis : longditudinal studies in a murine model of systemic lupus erythematosus 

      Tveita, Anders Aune (Doctoral thesis; Doktorgradsavhandling, 2010-12-15)
      Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that predominantly affects young women. Knowledge of the processes underlying the development of autoimmunity as well as end-organ disease manifestations is limited. One of the major contributors to morbidity and mortality in SLE patients is the development of nephritis. Using a murine model of SLE we have characterized ...
    • Ambiguity and professional accountability in physiotherapy practice. Acquired brain injury rehabilitation across health care levels 

      Irgens, Eirik Lind (Doctoral thesis; Doktorgradsavhandling, 2019-09-10)
      At the time of this study, the Norwegian health care system was in the middle of the implementation of the Coordination reform, initiated in 2012 due to insufficient coordination and an increase in health care service expenditure. Earlier hospital discharge and increased municipal responsibilities for rehabilitation following acquired brain injuries (ABI) challenge the traditional rehabilitation ...
    • Analysis of the Vibrionaceae pan-genome 

      Kahlke, Tim (Doctoral thesis; Doktorgradsavhandling, 2013-06-21)
      In the presented work the bacterial family Vibrionaceae was used as a model to investigate bacterial diversity on a gene level and to analyze the underlying concepts of bacterial niche adaptation and evolution. For this, the genomes of a diverse dataset of 64 Vibrionaceae isolates from various environments and temperature zones were analyzed using existing as well as newly developed bioinformatics ...
    • Androgen receptor CAG and GGN polymorphisms in vivo and in vitro 

      Skjærpe, Paal André (Doctoral thesis; Doktorgradsavhandling, 2012-09-21)
      Mannens testosteronnivå påvirkes av genetiske variasjoner i androgenreseptorens lengde selv om sammenhangen er beskjeden. Studier på celler har også vist at den vanligste androgenreseptoren lengden er den mest effektive. I studien Androgen receptor CAG og GGN polymorfier in vivo og in vitro har vi studert sammenhengen mellom genetiske variasjoner i androgenreseptorens lengde og testosteronnivåer ...
    • Angiogenic biomarkers in prostate cancer - A study into the prognostic significance of angiogenesis related growth factor ligands and receptors and miR-205 in a cohort of Norwegian prostatectomy patients 

      Nordby, Yngve (Doctoral thesis; Doktorgradsavhandling, 2018-05-03)
      Background: Prostate cancer is a heterogeneous disease, ranging from indolent and slow growing, to aggressive and lethal. Due to insufficient prognostic tools, there is a significant overtreatment of patients with harmless disease. Differentiating which patients benefit from radical treatments remains a huge challenge, and there is an urgent need to find new and better prognostic tools that may aid ...
    • Angiogenic markers as prognostic factors in non-small cell lung cancer (NSCLC) 

      Stenvold, Helge (Doctoral thesis; Doktorgradsavhandling, 2014-01-31)
    • Angiotensin II and heart remodelling : role of ischemia, gender and pregnancy 

      Aljabri, Mohammad Belal (Doctoral thesis; Doktorgradsavhandling, 2011-05-26)
      In this thesis different factors that promote or inhibit heart remodelling induced by angiotensin II were studied. The following conclusions can be drawn: 1. The presence of elevated levels of Ang II in the perfusion buffer did not increase myocardial injury during ischemia-reperfusion. However, the ability to protect the heart by ischemic postconditioning was lost. This seemed to be due to ...