Blar i forfatter "Vineis, Paolo"

Viser treff 21-40 av 60

    • Dietary folate intake and pancreatic cancer risk: Results from the European prospective investigation into cancer and nutrition 

      Park, Jin Young; Bueno-de-Mesquita, Hendrik Bastiaan; Ferrari, Pietro; Weiderpass, Elisabete; de Batlle, Jordi; Tjønneland, Anne; Kyrø, Cecilie; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Kritikou, Maria; Masala, Giovanna; Pala, Valeria; Tumino, Rosario; Panico, Salvatore; Peeters, Petra H.; Skeie, Guri; Merino, Susana; Duell, Eric J.; Rodríguez-Barranco, Miguel; Dorronsoro, Miren; Chirlaque, Maria-Dolores; Ardanaz, Eva; Gylling, Björn; Schneede, Jørn; Ericson, Ulrika; Sternby, Hanna; Khaw, Kay-Tee; Bradbury, Kathryn E.; Huybrechts, Inge; Aune, Dagfinn; Vineis, Paolo; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-04)
      Pancreatic cancer (PC) has an exceptionally low survival rate and primary prevention strategies are limited. Folate plays an important role in one‐carbon metabolism and has been associated with the risk of several cancers, but not consistently with PC risk. We aimed to investigate the association between dietary folate intake and PC risk, using the standardised folate database across 10 European ...

    • DNA methylation and associated gene expression in blood prior to lung cancer diagnosis in the Norwegian Women and Cancer cohort 

      Sandanger, Torkjel M; Nøst, Therese Haugdahl; Guida, Florence; Rylander, Charlotta; Campanella, Gianluca; Muller, David C; Van Dongen, Jenny; Boomsma, Dorret I; Johansson, Mattias; Vineis, Paolo; Vermeulen, Roel; Lund, Eiliv; Chadeau-Hyam, Marc (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-13)
      The majority of lung cancer is caused by tobacco smoking, and lung cancer-relevant epigenetic markers have been identified in relation to smoking exposure. Still, smoking-related markers appear to mediate little of the effect of smoking on lung cancer. Thus in order to identify disease-relevant markers and enhance our understanding of pathways, a wide search is warranted. Through an epigenome-wide ...

    • DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk 

      Baglietto, Laura; Ponzi, Erica; Haycock, Philip; Hodge, Allison; Bianca Assumma, Manuela; Jung, Chol-Hee; Chung, Jessica; Fasanelli, Francesca; Guida, Florence; Campanella, Gianluca; Chadeau-Hyam, Marc; Grankvist, Kjell; Johansson, Mikael; Ala, Ugo; Provero, Paolo; Wong, Ee Ming; Joo, Jihoon; English, Dallas R.; Kazmi, Nabila; Lund, Eiliv; Faltus, Christian; Risch, Angela; Barrdahl, Myrto; Sandanger, Torkjel M; Southey, Melissa C.; Giles, Graham G.; Johansson, Mattias; Vineis, Paolo; Polidoro, Silvia; Relton, Caroline L.; Severi, Gianluca (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-15)
      DNA methylation changes are associated with cigarette smoking. We used the Illumina Infinium HumanMethylation450 array to determine whether methylation in DNA from pre‐diagnostic, peripheral blood samples is associated with lung cancer risk. We used a case‐control study nested within the EPIC‐Italy cohort and a study within the MCCS cohort as discovery sets (a total of 552 case‐control pairs). We ...

    • DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility 

      Ambatipudi, Srikant; Horvath, Steve; Perrier, Flavie; Cuenin, Cyrille; Hernandez-Vargas, Hector; Le Calvez-Kelm, Florence; Durand, Geoffroy; Byrnes, Graham; Ferrari, Pietro; Bouaoun, Liacine; Sklias, Athena; Chajès, Véronique; Overvad, Kim; Severi, Gianluca; Baglietto, Laura; Clavel-Chapelon, Françoise; Kaaks, Rudolf; Barrdahl, Myrto; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Naska, Androniki; Masala, Giovanna; Agnoli, Claudia; Polidoro, Silvia; Tumino, Rosario; Panico, Salvatore; Dollé, Martijn; Peeters, Petra H.M.; Onland-Moret, N. Charlotte; Sandanger, Torkjel M; Nøst, Therese Haugdahl; Weiderpass, Elisabete; Quirós, José Ramón; Agudo, Antonio; Rodriguez-Barranco, Miguel; Huerta Castaño, José María; Barricarte, Aurelio; Fernández, Ander Matheu; Travis, Ruth C.; Vineis, Paolo; Muller, David C.; Riboli, Elio; Gunter, Marc; Romieu, Isabelle; Herceg, Zdenko (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-28)
      Aim of the study: A vast majority of human malignancies are associated with ageing, and age is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing, known as ‘epigenetic clock’, has been linked with cancer risk factors. This study aimed to evaluate whether the epigenetic clock is associated with breast cancer risk susceptibility and to identify potential epigenetics-based ...

    • Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking 

      Petrovic, Dusan; Bodinier, Barbara; Dagnino, Sonia; Whitaker, Matthew; Karimi, Maryam; Campanella, Gianluca; Nøst, Therese Haugdahl; Polidoro, Silvia; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Lund, Eiliv; Dugué, Pierre-Antoine; Giles, Graham G; Severi, Gianluca; Southey, Melissa; Vineis, Paolo; Stringhini, Silvia; Bochud, Murielle; Sandanger, Torkjel M; Vermeulen, Roel CH; Guida, Florence; Chadeau-Hyam, Marc (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-20)
      Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of CpG sites predicting lung cancer and explored the role of smoking in these associations. We analysed CpGs in relation to lung cancer in participants from two nested case–control studies, using (LASSO)-penalised ...

    • Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis 

      van Veldhoven, Karin; Polidoro, Silvia; Baglietto, Laura; Severi, Gianluca; Sacerdote, Carlotta; Panico, Salvatore; Mattiello, Amalia; Palli, Domenico; Masala, Giovanna; Krogh, Vittorio; Agnoli, Claudia; Tumino, Rosario; Frasca, Graziella; Flower, Kirsty; Curry, Ed; Orr, Nicholas; Tomczyk, Katarzyna; Jones, Michael E.; Ashworth, Alan; Swerdlow, Anthony; Chadeau-Hyam, Marc; Lund, Eiliv; Garcia-Closas, Montserrat; Sandanger, Torkjel M; Flanagan, James M.; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-04)
      Background: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast cancer. We report on three independent prospective nested case-control studies from the European ...

    • Fiber intake modulates the association of alcohol intake with breast cancer 

      Romieu, Isabelle; Ferrari, Pietro; Chajès, Véronique; de Batlle, Jordi; Biessy, Carine; Scoccianti, Chiara; Dossus, Laure; Boutron, Marie Christine; Bastide, Nadia; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Gils, Carla H.; Peeters, Petra H.; Lund, Eiliv; Skeie, Guri; Weiderpass, Elisabete; Quirós, J Ramón; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sánchez, María-José; Duell, Eric J.; Amiano Etxezarreta, Pilar; Borgquist, Signe; Hallmans, Göran; Johansson, Ingegerd; Nilsson, Lena Maria; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Murphy, Neil; Wark, Petra A.; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-06)
      Alcohol intake has been related to an increased risk of breast cancer (BC) while dietary fiber intake has been inversely associated to BC risk. A beneficial effect of fibers on ethanol carcinogenesis through their impact on estrogen levels is still controversial. We investigated the role of dietary fiber as a modifying factor of the association of alcohol and BC using data from the European Prospective ...

    • Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort 

      Engeset, Dagrun; Braaten, Tonje; Teucher, Birgit; Kuhn, Tilman; Bueno-de-Mesquita, HB; Leenders, Max; Agudo, Antonio; Bergmann, Manuela M; Valanou, Elisavet; Naska, Androniki; Trichopoulou, Antonia; Key, Timothy J; Crowe, Francesca L; Overvad, Kim; Sonestedt, Emily; Mattiello, Amalia; Peeters, Petra H; Wennberg, Maria; Jansson, Jan Håkan; Boutron-Ruault, Marie-Christine; Dossus, Laure; Dartois, Laureen; Li, Kuanrong; Barricarte, Aurelio; Ward, Heather; Riboli, Elio; Agnoli, Claudia; Huerta, Jose Maria; Sanchez, Maria-Jose; Tumino, Rosario; Altzibar, Jone M; Vineis, Paolo; Masala, Giovanna; Ferrari, Pietro; Muller, David C; Johansson, Mattias; Luisa Redondo, M; Tjønneland, A; Olsen, Anja; Olsen, Karina Standahl; Brustad, Magritt; Skeie, Guri; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study 

      Hanley-Cook, Giles T.; Huybrechts, Inge; Biessy, Carine; Remans, Roseline; Kennedy, Gina; Deschasaux-Tanguy, Mélanie; Murray, Kris A.; Touvier, Mathilde; Skeie, Guri; Kesse-Guyot, Emmanuelle; Argaw, Alemayehu; Casagrande, Corinne; Nicolas, Geneviève; Vineis, Paolo; Millett, Christopher J.; Weiderpass, Elisabete; Ferrari, Pietro; Dahm, Christina C.; Bueno-De-Mesquita, H. Bas; Sandanger, Torkjel M; Ibsen, Daniel B.; Freisling, Heinz; Ramne, Stina; Jannasch, Franziska; van der Schouw, Yvonne T.; Schulze, Matthias B.; Tsilidis, Konstantinos K.; Tjønneland, Anne; Ardanaz, Eva; Bodén, Stina; Cirera, Lluís; Gargano, Giuliana; Halkjær, Jytte; Jakszyn, Paula; Johansson, Ingegerd; Katzke, Verena; Masala, Giovanna; Panico, Salvatore; Rodriguez-Barranco, Miguel; Sacerdote, Carlotta; Srour, Bernard; Tumino, Rosario; Riboli, Elio; Gunter, Marc J.; Jones, Andrew D.; Lachat, Carl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background<p> <p>Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets ...

    • Food processing and cancer risk in Europe: results from the prospective EPIC cohort study 

      Kliemann, Nathalie; Rauber, Fernanda; Bertazzi Levy, Renata; Viallon, Vivian; Vamos, Eszter P; Cordova, Reynalda; Freisling, Heinz; Casagrande, Corinne; Nicolas, Genevieve; Aune, Dagfinn; Tsilidis, Konstantinos K; Heath, Alicia; Schulze, Matthias B; Jannasch, Franziska; Srour, Bernard; Kaaks, Rudolf; Rodriguez-Barranco, Miguel; Tagliabue, Giovanna; Agudo, Antonio; Panico, Salvatore; Ardanaz, Eva; Chirlaque, María-Dolores; Vineis, Paolo; Tumino, Rosario; Perez-Cornago, Aurora; Andersen, Julie Louise Munk; Tjønneland, Anne; Skeie, Guri; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J; Millett, Christopher; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-06)
      Background - Food processing has been hypothesised to play a role in cancer development; however, data from large-scale epidemiological studies are scarce. This study investigated the association between dietary intake according to amount of food processing and risk of cancer at 25 anatomical sites using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.<p> ...

    • Human endogenous retroviruses and cancer prevention: evidence and prospects 

      Cegolon, Luca; Salata, Cristiano; Weiderpass, Elisabete; Vineis, Paolo; Palu, Giorgio; Mastrangelo, Giuseppe (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Cancer is a significant and growing problem worldwide. While this increase may, in part, be attributed to increasing longevity, improved case notifications and risk-enhancing lifestyle (such as smoking, diet and obesity), hygiene-related factors resulting in immuno-regulatory failure may also play a major role and call for a revision of vaccination strategies to protect against a range of cancers ...

    • Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts 

      Fasanelli, Francesca; Baglietto, Laura; Ponzi, Erica; Guida, Florence; Campanella, Gianluca; Johansson, Mattias; Grankvist, Kjell; Johansson, Mikael; Assumma, Manuela Bianca; Naccarati, Alessio; Chadeau-Hyam, Marc; Ala, Ugo; Faltus, Christian; Kaaks, Rudolf; Risch, Angela; De Stavola, Bianca; Hodge, Allison; Giles, Graham G.; Southey, Melissa C.; Relton, Caroline L.; Haycock, Philip C.; Lund, Eiliv; Polidoro, Silvia; Sandanger, Torkjel M; Severi, Gianluca; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-15)
      DNA hypomethylation in certain genes is associated with tobacco exposure but it is unknown whether these methylation changes translate into increased lung cancer risk. In an epigenome-wide study of DNA from pre-diagnostic blood samples from 132 case–control pairs in the NOWAC cohort, we observe that the most significant associations with lung cancer risk are for cg05575921 in AHRR (OR for 1 s.d.=0.37, ...

    • IARC monographs: 40 years of evaluating carcinogenic hazards to humans 

      Pearce, Neil; Blair, Aaron; Vineis, Paolo; Ahrens, Wolfgang; Andersen, Aage; Anto, Josep M.; Armstrong, Bruce K.; Baccarelli, Andrea A.; Beland, Frederick A.; Berrington, Amy; Bertazzi, Pier Alberto; Birmbaum, Linda S.; Brownson, Ross C.; Bucher, John R.; Cantor, Kenneth P.; Cardis, Elisabeth; Cherrie, John W.; Christiani, David C.; Cocco, Pierluigi; Coggon, David; Comba, Pietro; Demers, Paul A.; Dement, John M.; Douwes, Jerouen; Eisen, Ellen A.; Engel, Lawrence S.; Fenske, Richard A.; Fleming, Lora E.; Fletcher, Tony; Fontham, Elizabeth; Forastiere, Francesco; Frentzel-Beyme, Rainer; Fritschi, Lin; Gerin, Michel; Goldberg, Marcel; Grandjean, Philippe; Grimsrud, Tom Kristian; Gustavsson, Per; Haines, Andy; Hartge, Patricia; Hansen, Johnni; Hauptmann, Michael; Heederick, Dick; Hemminki, Kari; Hemon, Denis; Hertz-Picciotto, Irva; Hoppin, Jane A.; Huff, James; Jarvholm, Bengt; Kang, Daehee; Karagas, Margaret R.; Kjærheim, Kristina; Kjuus, Helge; Kogevinas, Manolis; Kriebel, David; Kristensen, Petter; Kromhout, Hans; Laden, Francine; Lebailly, Pierre; LeMasters, Grace; Lubin, Jay H.; Lynch, Charles F.; Lynge, Elsebeth; ‘t Mannetje, Andrea; McMichael, Anthony J.; McLaughlin, John R.; Marrett, Loraine; Martuzzi, Marco; Merchant, James A.; Merler, Enzo; Merletti, Franco; Miller, Anthony; Mirer, Franklin E.; Monson, Richard; Nordby, Karl-Christian; Olshan, Andrew F.; Parent, Marie-Elise; Perera, Frederica P.; Perry, Melissa J.; Pesatori, Angela Cecilia; Pirastu, Roberta; Porta, Miquel; Pukkala, Eero; Rice, Carol; Richardson, David B.; Ritter, Leonard; Ritz, Beate; Ronckers, Cecile M.; Rushton, Lesley; Rusiecki, Jennifer A.; Rusyn, Ivan; Samet, Jonathan M.; Sandler, Dale P.; de Sanjose, Silvia; Schernhammer, Eva; Costantini, Adele Seniori; Seixas, Noah; Shy, Carl; Siemiatycki, Jack; Silverman, Debra T.; Simonato, Lorenzo; Smith, Allan H.; Smith, Martyn T.; Spinelli, John J.; Spitz, Margaret R.; Stallones, Lorann; Stayner, Leslie T.; Steenland, Kyle; Stenzel, Mark; Stewart, Bernard W.; Stewart, Patricia A.; Symanski, Elaine; Terracini, Benedetto; Tolbert, Paige E.; Vainio, Harri; Vena, John; Vermeulen, Roel; Victora, Cesar G.; Ward, Elizabeth M.; Weinberg, Clarice R.; Weisenburger, Dennis; Wesseling, Catharina; Weiderpass, Elisabete; Zahm, Shelia Hoar (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-24)
      Background: Recently, the International Agency for Research on Cancer (IARC) Programme for the Evaluation of Carcinogenic Risks to Humans has been criticized for several of its evaluations, and also for the approach used to perform these evaluations. Some critics have claimed that failures of IARC Working Groups to recognize study weaknesses and biases of Working Group members have led to inappropriate ...

    • Identifying and correcting epigenetics measurements for systematic sources of variation 

      Perrier, Flavie; Novoloaca, Alexei; Ambatipudi, Srikant; Baglietto, Laura; Ghantous, Akram; Perduca, Vittorio; Barrdahl, Myrto; Harlid, Sophia; Ong, Ken K; Cardona, Alexia; Polidoro, Silvia; Nøst, Therese Haugdahl; Overvad, Kim; Omichessan, Hanane; Dollé, Martijn; Bamia, Christina; Huerta, José María; Vineis, Paolo; Herceg, Zdenko; Romieu, Isabelle; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-21)
      <i>Background</i>: Methylation measures quantified by microarray techniques can be affected by systematic variation due to the technical processing of samples, which may compromise the accuracy of the measurement process and contribute to bias the estimate of the association under investigation. The quantification of the contribution of the systematic source of variation is challenging in datasets ...

    • Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries : a prospective study 

      Lund, Eiliv; Vineis, Paolo; Hoek, Gerald; Krzyzanowski, Michal; Vigna-Taglianti, Federica; Veglia, Fabrizio; Airoldi, Luisa; Raaschou-Nielsen, Ole; Clavel-Chapelon, Francoise; Linseisen, Jacob; Boeing, Heiner; Trichopoulou, Antonia; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Agudo, Antonio; Martinez, Carmen; Dorronsoro, Miren; Barricarte, Aurelio; Cirera, Lluis; Quiros, J Ramon; Berglund, Gøran; Manjer, Jonas; Forsberg, Bertil; Day, Nicholas E.; Key, Tim J.; Kaaks, Rudolf; Saracci, Rodolfo; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2007-02-15)
      Background: Several countries are discussing new legislation on the ban of smoking in public places, and on the acceptable levels of traffic-related air pollutants. It is therefore useful to estimate the burden of disease associated with indoor and outdoor air pollution. Methods: We have estimated exposure to Environmental Tobacco Smoke (ETS) and to air pollution in never smokers and ex-smokers ...

    • Measured adiposity in relation to head and neck cancer risk in the European prospective investigation into cancer and nutrition. 

      Ward, Heather A.; Wark, Petra A.; Muller, David C.; Steffen, Annika; Johansson, Mattias; Norat, Teresa; Gunter, Marc J.; Overvad, Kim; Dahm, Christina C; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Mesrine, Sylvie; Brennan, Paul; Freisling, Heinz; Li, Kuanrong; Kaaks, Rudolf; Trichopoulou, Antonia; Lagiou, Pagona; Panico, Salavatore; Grioni, Sara; Tumino, Rosario; Vineis, Paolo; Palli, Domenico; Peeters, Petra H.M.; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Agudo, Antonio; Quirós, José Ramón; Larrañaga, Nerea; Ardanaz, Eva; Huerta, José María; Sánchez, María-José; Laurell, Göran; Johansson, Ingegerd; Westin, Ulla; Wallström, Peter; Bradbury, Kathryn E.; Wareham, Nicholas J.; Khaw, Kay-Tee; Pearson, Clare; Boeing, Heiner; Riboli, Elio (Journal article; Tidsskriftartikkel, 2017-06)
      <b>Background</b>: Emerging evidence from cohort studies indicates that adiposity is associated with greater incidence of head and neck cancer. However, most studies have used self-reported anthropometry which is prone to error.<br><b>Methods</b>: Among 363,094 participants in the European Prospective Investigation into Cancer and Nutrition study (EPIC) with measured anthropometry, there were 837 ...

    • Mediating Role of Lifestyle Behaviors in the Association between Education and Cancer: Results from the European Prospective Investigation into Cancer and Nutrition 

      Macciotta, Alessandra; Catalano, Alberto; Giraudo, Maria Teresa; Weiderpass, Elisabete; Ferrari, Pietro; Freisling, Heinz; Colorado-Yohar, Sandra M.; Santiuste, Carmen; Amiano, Pilar; Heath, Alicia K.; Ward, Heather A.; Christakoudi, Sofia; Vineis, Paolo; Singh, Deependra; Vaccarella, Salvatore; Schulze, Matthias B.; Hiensch, Anouk E.; Monninkhof, Evelyn M.; Katzke, Verena; Kaaks, Rudolf; Tumino, Rosario; Lazzarato, Fulvio; Milani, Lorenzo; Agudo, Antonio; Dahm, Christina C.; Baglietto, Laura; Perduca, Vittorio; Severi, Gianluca; Grioni, Sara; Panico, Salvatore; Ardanaz, Eva; Borch, Kristin Benjaminsen; Benebo, Faith Owunari; Braaten, Tonje; Sánchez, Maria-Jose; Giachino, Claudia; Sacerdote, Carlotta; Ricceri, Fulvio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-09)
      Background: Many studies have shown that socioeconomic position (SEP) is associated with the incidence of malignant tumors at different sites. This study aims to estimate the association between educational level (as proxy for SEP) and cancer incidence and to understand whether the observed associations might be partially explained by lifestyle behaviors.<p> <p>Methods: The analyses were performed ...

    • Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia 

      Berndt, Sonja I.; Camp, Nicola J.; Skibola, Christine F.; Vijai, Joseph; Wang, Zhaoming; Gu, Jian; Nieters, Alexandra; Kelly, Rachel S; Smedby, Karin E.; Monnereau, Alain; Cozen, Wendy; Cox, Angela; Wang, Sophia S.; Lan, Qing; Teras, Lauren R; Machado, Moara; Yeager, Meredith; Brooks-Wilson, Angela R.; Hartge, Patricia; Purdue, Mark P.; Birmann, Brenda M.; Vajdic, Claire M.; Cocco, Pierluigi; Zhang, Yawei; Giles, Graham G.; Zeleniuch-Jacquotte, Anne; Lawrence, Charles; Montalvan, Rebecca; Burdett, Laurie; Hutchinson, Amy; Ye, Yuanqing; Call, Timothy G.; Shanafelt, Tait D.; Novak, Anne J.; Kay, Neil E.; Liebow, Mark; Cunningham, Julie M.; Allmer, Cristine; Hjalgrim, Henrik; Adami, Hans-Olov; Melbye, Mads; Glimelius, Bengt; Chang, Ellen T.; Glenn, Martha; Curtin, Karen; Cannon-Albright, Lisa A.; Diver, W Ryan; Link, Brian K.; Weiner, George J.; Conde, Lucia; Bracci, Paige M.; Riby, Jacques; Arnett, Donna K.; Zhi, Degui; Leach, Justin M.; Holly, Elizabeth A.; Jackson, Rebecca D.; Tinker, Lesley F.; Benavente, Yolanda; Sala, Nuria; Casabonne, Delphine; Becker, Nikolaus; Boffetta, Paolo; Brennan, Paul; Foretova, Lenka; Maynadie, Marc; McKay, James; Staines, Anthony; Chaffee, Kari G.; Achenbach, Sara J.; Vachon, Celine M.; Goldin, Lynn R.; Strom, Sara S.; Leis, Jose F.; Weinberg, J. Brice; Caporaso, Neil E.; Norman, Aaron D.; De Roos, Anneclaire J.; Morton, Lindsay M.; Severson, Richard K.; Riboli, Elio; Vineis, Paolo; Kaaks, Rudolph; Masala, Giovanna; Weiderpass, Elisabete; Chirlaque, Maria-Dolores; Vermeulen, Roel C.H.; Travis, Ruth C.; Southey, Melissa C.; Milne, Roger L.; Albanes, Demetrius; Virtamo, Jarmo; Weinstein, Stephanie; Clavel, Jacqueline; Zheng, Tongzhang; Holford, Theodore R.; Villano, Danylo J.; Maria, Ann; Spinelli, John J.; Gascoyne, Randy D.; Connors, Joseph M.; Bertrand, Kimberly A.; Giovannucci, Edward; Kraft, Peter; Kricker, Anne; Turner, Jenny; Ennas, Maria Grazia; Ferri, Giovanni M.; Miligi, Lucia; Liang, Liming; Ma, Baoshan; Huang, Jinyan; Crouch, Simon; Park, Ju-Hyun; Chatterjee, Nilanjan; North, Kari E.; Snowden, John A.; Wright, Josh; Fraumeni, Joseph F.; Offit, Kenneth; Wu, Xifeng; De Sanjose, Silvia; Cerhan, James R.; Chanock, Stephen J.; Rothman, Nathaniel; Slager, Susan L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-09)
      Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy with strong heritability. To further understand the genetic susceptibility for CLL and identify common loci associated with risk, we conducted a meta-analysis of four genome-wide association studies (GWAS) composed of 3,100 cases and 7,667 controls with follow-up replication in 1,958 cases and 5,530 controls. Here we report three new ...

    • Methodological issues in a prospective study on plasma concentrations of persistent organic pollutants and pancreatic cancer risk within the EPIC cohort 

      Gasull, Magda; Pumarega, José; Kiviranta, Hannu; Rantakokko, Panu; Raaschou-Nielsen, Ole; Bergdahl, Ingvar A.; Sandanger, Torkjel M; Goñi, Fernando; Cirera, Lluís; Donat-Vargas, Carolina; Alguacil, Juan; Iglesias, Mar; Tjønneland, Anne; Overvad, Kim; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Johnson, Theron; Kühn, Tilman; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Verschuren, Monique; Vermeulen, Roel; Rylander, Charlotta; Nøst, Therese Haugdahl; Rodriguez-Barranco, Miguel; Molinuevo, Amaia; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sund, Malin; Key, Tim; Ye, Weimin; Jenab, Mazda; Michaud, Dominique; Matullo, Giuseppe; Canzian, Federico; Kaaks, Rudolf; Nieters, Alexandra; Nöthlings, Ute; Jeurnink, Suzanne; Chajes, Veronique; Matejcic, Marco; Gunter, Marc; Aune, Dagfinn; Riboli, Elio; Agudo, Antoni; Gonzalez, Carlos Alberto; Weiderpass, Elisabete; Bueno-de-Mesquita, Hendrik Bastiaan; Duell, Eric J.; Vineis, Paolo; Porta, Miquel (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-23)
      <i>Background</i> - The use of biomarkers of environmental exposure to explore new risk factors for pancreatic cancer presents clinical, logistic, and methodological challenges that are also relevant in research on other complex diseases.<p> <p><i>Objectives</i> - First, to summarize the main design features of a prospective case-control study –nested within the European Prospective Investigation ...

    • Modifiable causes of premature death in middle-age in Western Europe: Results from the EPIC cohort study 

      Muller, David C.; Murphy, Neil; Johansson, Mattias; Ferrari, Pietro; Tsilidis, Konstantinos K.; Boutron-Ruault, Marie-Christine; Clavel, Francoise; Dartois, Laureen; Li, Kuanrong; Kaaks, Rudolf; Weikert, Cornelia; Bergmann, Manuela; Boeing, Heiner; Tjønneland, Anne; Overvad, Kim; Redondo, María-Luisa; Agudo, Antonio; Molina-Portillo, Elena; Altzibar, Jone M.; Cirera, Lluis; Ardanaz, Eva; Khaw, Kay-Tee; Wareham, Nicholas J.; Key, Timothy J.; Travis, Ruth C.; Bamia, Christina; Orfanos, Philippos; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Verschuren, W.M. Monique; Struijk, Ellen A.; Peeters, Petra H.; Engström, Gunnar; Melander, Olle; Sund, Malin; Weiderpass, Elisabete; Skeie, Guri; Lund, Eiliv; Norat, Teresa; Gunter, Marc; Riboli, Elio; Brennan, Paul (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-14)
      Background<br> Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, hypertension, obesity, physical inactivity, alcohol and poor diet towards risk of premature death.<br> Methods<br> We analysed data from 264,906 European adults from the ...