Blar i forfatter "Aas, Monica"

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    • Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders 

      Reponen, Elina Johanna; Dieset, Ingrid; Tesli, Martin Steen; Mørch, Ragni Helene; Aas, Monica; Vedal, Trude Seselie Jahr; Haug, Elisabeth; Drange, Ole Kristian; Steen, Nils Eiel; Hope, Sigrun; Szabo, Attila; Gohar, Sherif Mostafa Mohamed Ahmed; Wedervang-Resell, Kirsten; Djurovic, Srdjan; Melle, Ingrid; Aukrust, Pål; Andreassen, Ole Andreas; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-10)
      <p><i>Background:</i> Cardiovascular disease (CVD) is a major cause of premature death in patients with psychotic disorders, where dyslipidemia occurs frequently. In the pathogenesis of these serious mental disorders, a low-grade inflammation seems to be a possible contributor. Concurrently, systemic inflammation and its interplay with dyslipidemia is a central driver in the pathogenesis of CVD. We ...

    • Cortisol and C-reactive protein (CRP) regulation in severe mental disorders 

      Inova, Amina; Birkenæs, Viktoria; Quintana, Daniel; Ormerod, Monica Bettina E. Greenwood; Ueland, Torill; Ueland, Thor; Djurovic, Srdjan; Andreassen, Ole; Steen, Nils Eiel; Aas, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-12-25)
      Background - People with schizophrenia (SZ) and bipolar disorder (BD) show abnormalities in the biological stress system and low-grade inflammation. However, whether the hypothalamic-pituitary-adrenal (HPA) axis-immune regulation is disrupted in SZ and BD, is yet to be determined.<p> <p>Methods - Cortisol and C-reactive protein (CRP) were measured in blood samples collected at or before 10 am in ...

    • Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers 

      Reponen, Elina Johanna; Ueland, Thor; Rokicki, Jaroslav; Bettella, Francesco; Aas, Monica; Werner, Maren C. F.; Dieset, Ingrid; Steen, Nils E.; Andreassen, Ole A.; Tesli, Martin Steen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-05)
      Individuals with schizophrenia and bipolar disorder are at an increased risk of cardiovascular disease (CVD), and a range of biomarkers related to CVD risk have been found to be abnormal in these patients. Common genetic factors are a putative underlying mechanism, alongside lifestyle factors and antipsychotic medication. However, the extent to which the altered CVD biomarkers are related to genetic ...

    • Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders 

      Aas, Monica; Dieset, Ingrid; Mørch, Ragni Helene; Steen, Nils Eiel; Hope, Sigrun; Reponen, Elina Johanna; Anderssen, Jannicke Fjæra; Ueland, Thor; Aukrust, Pål; Melle, Ingrid; Agartz, Ingrid; Andreassen, Ole Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-17)
      <p><i>Background - </i>Although several studies have found reduced plasma BDNF levels in patients with severe mental disorders, the sample sizes have been small and have exhibited variation and heterogeneity. Furthermore, long-term neurobiological changes following childhood trauma and clinical severity have been linked to a reduction in BDNF levels. Accordingly, we aim to clarify, using the largest ...