Blar i forfatter "Bakksjø, Ragna-Johanne"

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    • Exploring Klebsiella pneumoniae in Healthy Poultry Reveals High Genetic Diversity, Good Biofilm-Forming Abilities and Higher Prevalence in Turkeys Than Broilers 

      Franklin-Alming, Fiona; Kaspersen, Håkon; Hetland, Marit A. K.; Bakksjø, Ragna-Johanne; Nesse, Live L.; Leangapichart, Thongpan; Löhr, Iren Høyland; Telke, Amar; Sunde, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-07)
      Klebsiella pneumoniae is a well-studied human pathogen for which antimicrobial resistant and hypervirulent clones have emerged globally. K. pneumoniae is also present in a variety of environmental niches, but currently there is a lack of knowledge on the occurrence and characteristics of K. pneumoniae from non-human sources. Certain environmental niches, e.g., animals, may be associated with high ...

    • A nationwide genomic study of clinical Klebsiella pneumoniae in Norway 2001–15: introduction and spread of ESBLs facilitated by clonal groups CG15 and CG307 

      Fostervold, Aasmund; Hetland, Marit Andrea Klokkhammer; Bakksjø, Ragna-Johanne; Bernhoff, Eva; Holt, Kathryn E.; Samuelsen, Ørjan; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn; Wyres, Kelly L.; Löhr, Iren Høyland (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-22)
      Objectives: To use the nationwide Norwegian surveillance programme on resistant microbes in humans (NORM) to address longitudinal changes in the population structure of Klebsiella pneumoniae isolates from 2001–15, focusing on the emergence and dissemination of ESBL-producing K. pneumoniae in Norway.<p> <p>Methods: Among blood (n = 6124) and urinary tract (n = 5496) surveillance isolates from ...

    • Risk of death in Klebsiella pneumoniae bloodstream infections is associated with specific phylogenetic lineages 

      Fostervold, Aasmund; Raffelsberger, Niclas Peter; Hetland, Marit; Bakksjø, Ragna-Johanne; Bernhoff, Eva; Samuelsen, Ørjan; Sundsfjord, Arnfinn Ståle; Afset, Jan Egil; Berntsen, Christopher Friis; Bævre-Jensen, Roar Magne; Ebbesen, Marit Helen; Gammelsrud, Karianne Wiger; Guleng, Anja D.; Handal, Nina; Jakovljev, Aleksandra; Johal, Simreen Kaur; Marvik, Åshild; Natvik, Ane Kristine; Sandnes, Rolf-Arne; Tofteland, Ståle; Bjørnholt, Jørgen; Löhr, Iren Høyland (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-02)
      Background: Klebsiella pneumoniae species complex (KpSC) bloodstream infections (BSIs) are associated with considerable morbidity and mortality, particularly in elderly and multimorbid patients. Multidrugresistant (MDR) strains have been associated with poorer outcome. However, the clinical impact of KpSC phylogenetic lineages on BSI outcome is unclear. <p> <p>Methods: In an 18-month nationwide ...

    • Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17 

      Hetland, Marit; Hawkey, Jane; Bernhoff, Eva; Bakksjø, Ragna-Johanne; Kaspersen, Håkon; Rettedal, Siren; Sundsfjord, Arnfinn; Holt, Kathryn E.; Löhr, Iren Høyland (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-18)
      Klebsiella pneumoniae sequence type (ST) 17 is a global problem clone that causes multidrug-resistant (MDR) hospital infections worldwide. In 2008–2009, an outbreak of MDR ST17 occurred at a neonatal intensive care unit (NICU) in Stavanger, Norway. Fifty-seven children were colonized. We observed intestinal persistence of ST17 in all of the children for up to two years after hospital discharge. ...