Blar i forfatter "Håberg, Asta"
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Anatomical variations in the circle of Willis are associated with increased odds of intracranial aneurysms: The Tromsø study
Hindenes, Lars Bakke; Ingebrigtsen, Tor; Isaksen, Jørgen Gjernes; Håberg, Asta; Johnsen, Liv-Hege; Herder, Marit; Mathiesen, Ellisiv B.; Vangberg, Torgil Riise (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-25)Purpose: Studies on patients suggest an association between anatomical variations in the Circle of Willis (CoW) and intracranial aneurysms (IA), but it is unclear whether this association is present in the general population. In this cross-sectional population study, we investigated the associations between CoW anatomical variations and IA.<p> <p>Methods: We included 1667 participants from a ... -
Both brain size and biological sex contribute to variation in white matter microstructure in middle-aged healthy adults
Eikenes, Live; Visser, Eelke; Vangberg, Torgil Riise; Håberg, Asta (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-03)Whether head size and/or biological sex influence proxies of white matter (WM) microstructure such as fractional anisotropy (FA) and mean diffusivity (MD) remains controversial. Diffusion tensor imaging (DTI) indices are also associated with age, but there are large discrepancies in the spatial distribution and timeline of age-related differences reported. The aim of this study was to evaluate the ... -
Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study
van Veen, Ernest; Van Der Jagt, Mathieu; Cnossen, Maryse C.; Maas, Andrew I. R.; De Beaufort, Inez D.; Menon, David K.; Citerio, Giuseppe; Stocchetti, Nino; Rietdijk, Wim J. R.; van Dijck, Jeroen T. J. M.; Kompanje, Erwin J. O.; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Roise, Olav; Skandsen, Toril; Håberg, Asta; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-16)<p><i>Background</i>: We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation.</p> <p><i>Methods</i>: Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study centers completed several questionnaires (response rate: 99%).</p> <p><i>Results</i>: Regarding practices around ... -
Echoes from Intrinsic Connectivity Networks in the Subcortex
Groot, Josephine Maria; Miletic, Steven; Isherwood, Scott J.S.; Tse, Desmond H.Y.; Habli, Sarah; Håberg, Asta; Forstmann, Birte U.; Bazin, Pierre-Louis; Mittner, Matthias Bodo (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)Decades of research have greatly improved our understanding of intrinsic human brain organization in terms of functional networks and the transmodal hubs within the cortex at which they converge. However, substrates of multinetwork integration in the human subcortex are relatively uncharted. Here, we leveraged recent advances in subcortical atlasing and ultra-high field (7 T) imaging optimized for ... -
Five years of exercise intervention at different intensities and development of white matter hyperintensities in community dwelling older adults, a Generation 100 sub-study
Arild, Anette; Vangberg, Torgil Riise; Nikkels, Hanne; Lydersen, Stian; Wisløff, Ulrik; Stensvold, Dorthe; Håberg, Asta (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-18)We investigated if a five-year supervised exercise intervention with moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT) versus control; physical activity according to national guidelines, attenuated the growth of white matter hyperintensities (WMH). We hypothesized that supervised exercise, in particular HIIT, reduced WMH growth. Older adults from the general ... -
Post-Concussion Symptoms in Complicated vs. Uncomplicated Mild Traumatic Brain Injury Patients at Three and Six Months Post-Injury: Results from the CENTER-TBI Study
Voomolen, DC; Haagsma, JA; Polinder, Suzanne; Maas, AIR; Steyerberg, Ewout W; Vulekovic, Peter; Sewalt, CA; Gravesteijn, BY; Covic, Amra; Andelic, Nada; Plass, AM; von Steinbüchel, Nicole; Vik, Anne; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin Kordasti; Helseth, Eirik; Skandsen, Toril; Røise, Olav; Håberg, Asta; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-08)Abstract The aim of this study was to assess the occurrence of post-concussion symptoms and post-concussion syndrome (PCS) in a large cohort of patients after complicated and uncomplicated mild traumatic brain injury (mTBI) at three and six months post-injury. Patients were included through the prospective cohort study: Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI). Patients ... -
Predicting recovery in patients with mild traumatic brain injury and a normal CT using serum biomarkers and diffusion tensor imaging (CENTER-TBI): an observational cohort study
Richter, Sophie; Winzeck, Stefan; Correia, Marta M.; Czeiter, Endre; Whitehouse, Daniel; Kornaropoulos, Evgenios N.; Williams, Guy B.; Verheyden, Jan; Das, Tilak; Tenovuo, Olli; Posti, Jussi P.; Vik, Anne; Moen, Kent Gøran; Håberg, Asta; Wang, Kevin; Buki, Andras; Maas, Andrew; Steyerberg, Ewout; Menon, David K; Newcombe, Virginia F.J.; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Azouvi, Philippe; Bellander, Bo-michael; Benali, Habib; Caccioppola, Alessio; Calappi, Emiliana; Carbonara, Marco; Citerio, Giuseppe; Clusmann, Hans; Coburn, Mark; Coles, Jonathan; Correia, Marta; De Keyser, Véronique; Degos, Vincent; Depreitere, Bart; Eikenes, Live; Ezer, Erzsébet; Foks, Kelly; K Frisvold, Shirin; Galanaud, Damien; Ghuysen, Alexandre; Glocker, Ben; Haitsma, Iain; Helseth, Eirik; Nordhøy, Wibeke; Røe, Cecilie; Røise, Olav; Skandsen, Toril (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-08)Background - Even patients with normal computed tomography (CT) head imaging may experience persistent symptoms for months to years after mild traumatic brain injury (mTBI). There is currently no good way to predict recovery and triage patients who may benefit from early follow-up and targeted intervention. We aimed to assess if existing prognostic models can be improved by serum biomarkers or ... -
The prognostic importance of traumatic axonal injury on early MRI: the Trondheim TAI-MRI grading and quantitative models
Moen, Kent Gøran; Flusund, Anne-Mari Holte; Moe, Hans Kristian; Andelic, Nada; Skandsen, Toril; Håberg, Asta; Kvistad, Kjell Arne; Olsen, Øystein E.; Saksvoll, Elin Hildrum; Abel-Grüner, Sebastian; Anke, Audny Gabriele Wagner; Follestad, Turid; Vik, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-19)Objectives We analysed magnetic resonance imaging (MRI) findings after traumatic brain injury (TBI) aiming to improve the grading of traumatic axonal injury (TAI) to better reflect the outcome.<p> <p>Methods Four-hundred sixty-three patients (8–70 years) with mild (n = 158), moderate (n = 129), or severe (n = 176) TBI and early MRI were prospectively included. TAI presence, numbers, and volumes ... -
Repeat traumatic brain injury exacerbates acute thalamic hyperconnectivity in humans
Woodrow, Rebecca E; Menon, David K.; Stamatakis, Emmanuel A; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Azouvi, Philippe; Bellander, Bo-Michael; Benali, Habib; Buki, Andras; Caccioppola, Alessio; Calappi, Emiliana; Carbonara, Marco; Citerio, Giuseppe; Clusmann, Hans; Coburn, Mark; Coles, Jonathan; Correia, Marta; Czeiter, Endre; De Keyser, Véronique; Degos, Vincent; Depreitere, Bart; Eikenes, Live; Ezer, Erzsébet; Foks, Kelly; K Frisvold, Shirin; Galanaud, Damien; Ghuysen, Alexandre; Glocker, Ben; Håberg, Asta; Haitsma, Iain; Helseth, Eirik; Hutchinson, Peter J; Kornaropoulos, Evgenios; Kovács, Noémi; Kowark, Ana; Laureys, Steven; Ledoux, Didier; Lingsma, Hester; Maas, Andrew IR; Manley, Geoffrey; Menon, David K; Menovsky, Tomas; Misset, Benoit; Muraleedharan, Visakh; Nakken, Ingeborg; Newcombe, Virginia; Nordhøy, Wibeke; Skandsen, Toril; Vik, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-28)Repeated mild traumatic brain injury is of growing interest regarding public and sporting safety and is thought to have greater adverse or cumulative neurological effects when compared with single injury. While epidemiological links between repeated traumatic brain injury and outcome have been investigated in humans, exploration of its mechanistic substrates has been largely undertaken in animal ... -
Spousal bereavement and its effects on later life physical and cognitive capability: the Tromsø study
Strand, Bjørn Heine; Håberg, Asta; Eyjólfsdóttir, Harpa Sif; Kok, Almar; Skirbekk, Vegard Fykse; Huxhold, Oliver; Løset, Gøril Kvamme; Lennartsson, Carin; Schirmer, Henrik; Herlofson, Katharina; Veenstra, Marijke (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-09)Spousal bereavement is associated with health declines and increased mortality risk, but its specific impact on physical and cognitive capabilities is less studied. A historical cohort study design was applied including married Tromsø study participants (N=5739) aged 50–70 years with baseline self-reported overall health and health-related factors and measured capability (grip strength, finger ... -
Systemic inflammation persists the first year after mild traumatic brain injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study
Chaban, Viktoriia; Clarke, Gerard; Skandsen, Toril; Islam, Rakibul; Einarsen, Cathrine Elisabeth; Vik, Anne; Damås, Jan Kristian; Mollnes, Tom Eirik; Håberg, Asta; Pischke, Soeren (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-03)Innate immune activation has been attributed a key role in traumatic brain injury (TBI) and successive morbidity. In mild TBI (mTBI), however, the extent and persistence of innate immune activation are unknown. We determined plasma cytokine level changes over 12 months after an mTBI in hospitalized and non-hospitalized patients compared with community controls; and examined their associations to ... -
Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study
Huijben, Jilske A.; Volovici, Victor; Cnossen, Maryse C.; Haitsma, Iain K.; Stocchetti, Nino; Maas, Andrew I. R.; Menon, David K.; Ercole, Ari; Citerio, Giuseppe; Nelson, David; Polinder, Suzanne; Steyerberg, Ewout W.; Lingsma, Hester F.; van der Jagt, Mathieu; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Roise, Olav; Skandsen, Toril; Håberg, Asta; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-13)<p><i>Background</i>: General supportive and preventive measures in the intensive care management of traumatic brain injury (TBI) aim to prevent or limit secondary brain injury and optimize recovery. The aim of this survey was to assess and quantify variation in perceptions on intensive care unit (ICU) management of patients with TBI in European neurotrauma centers.</p> <p><i>Methods</i>: We ... -
Variations in the Circle of Willis in a large population sample using 3D TOF angiography: The Tromsø Study
Hindenes, Lars Bakke; Håberg, Asta; Johnsen, Liv-Hege; Mathiesen, Ellisiv B.; David, Robben; Vangberg, Torgil Riise (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-03)The main arteries that supply blood to the brain originate from the Circle of Willis (CoW). The CoW exhibits considerable anatomical variations which may have clinical importance, but the variability is insufficiently characterised in the general population. We assessed the anatomical variability of CoW variants in a community-dwelling sample (N = 1,864, 874 men, mean age = 65.4, range 40–87 years), ...