• Characterization of the circadian clock in Hooded Seals (Cystophora Cristata) and its interaction with mitochondrial metabolism A multi-tissue comparison and cell culture approach 

      Kante, Fayiri (Master thesis; Mastergradsoppgave, 2021-06-02)
      Circadian rhythms regulate living organisms over a 24h period. From daily activity to cellular function. The polar regions are subject to different photoperiods across the year, which impact the environmental conditions on a seasonal and daily basis. Evidence of crosstalk between circadian core clock genes and hypoxia with genes involved the mitochondrial dynamics, as well as oxygen sensing, provide ...
    • Circadian coupling of mitochondria in a deep-diving mammal 

      Ciccone, Chiara; Kante, Fayiri; Folkow, Lars; Hazlerigg, David Grey; West, Alexander Christopher; Wood, Shona Hiedi (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-08)
      Regulation of mitochondrial oxidative phosphorylation is essential to match energy supply to changing cellular energy demands, and to cope with periods of hypoxia. Recent work implicates the circadian molecular clock in control of mitochondrial function and hypoxia sensing. Because diving mammals experience intermittent episodes of severe hypoxia, with diel patterning in dive depth and duration, ...