• All that glitters is not gold: high uptake on PSMA PET in non-prostate cancers does not mean that treatment with [<177Lu]Lu-PSMA-radioligand will be successful 

      Bogsrud, Trond; Engelsen, Ola; Lu, Thi Thu Thuy; Stensvold, Andreas; Johnson, Derek R.; Burkett, Brian J.; Kendi, Ayse Tuba; Pandey, Mukesh K.; Sundset, Rune; Durski, Jolanta M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-15)
      Background The main objective is to discuss why treatment of non-prostate cancers with [<sup>177</sup>Lu]Lu-PSMAradioligand achieved only low tumor dose in most published cases, despite high uptake on PSMA PET. We use a patient with renal cell carcinoma as an illustrative example. Furthermore, we discuss how the problem with early washout and low tumor dose might be overcome by using a radionuclide ...