Blar i forfatter "Markussen, Fredrik Andreas Fasth"

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    • c-fos induction in the choroid plexus, tanycytes and pars tuberalis is an early indicator of spontaneous arousal from torpor in a deep hibernator 

      Markussen, Fredrik Andreas Fasth; Cázarez-Márquez, Fernando; Melum, Vebjørn Jacobsen; Hazlerigg, David Grey; Wood, Shona Hiedi (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-23)
      Hibernation is an extreme state of seasonal energy conservation, reducing metabolic rate to as little as 1% of the active state. During the hibernation season, many species of hibernating mammals cycle repeatedly between the active (aroused) and hibernating (torpid) states (T–A cycling), using brown adipose tissue (BAT) to drive cyclical rewarming. The regulatory mechanisms controlling this process ...

    • Hibernation in European Hamsters (Cricetus crisetus): An assessment of brain permeability during torpor-arousal cycling 

      Markussen, Fredrik Andreas Fasth (Master thesis; Mastergradsoppgave, 2020-05-22)
      Hibernation is a physiological and behavioural adaptation that permits survival during seasonal periods of energy shortage via a combination of pre-hibernal energy storage and hibernal metabolic depression, i.e. torpor. The central mechanisms in the brain that control torpor expression and arousal from it has been under investigation since the dawn of hibernation research but remains unknown. Recent ...

    • Hypothalamic tanycytes as mediators of maternally programmed seasonal plasticity 

      Melum, Vebjørn Jacobsen; Sáenz de Miera, Cristina; Markussen, Fredrik Andreas Fasth; Cazarez Marquez, Fernando; Jaeger, Catherine; Sandve, Simen Rød; Simonneaux, Valérie; Hazlerigg, David Grey; Wood, Shona Hiedi (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-12)
      In mammals, maternal photoperiodic programming (MPP) provides a means whereby juvenile development can be matched to forthcoming seasonal environmental conditions.<sup>1–4</sup> This phenomenon is driven by in utero effects of maternal melatonin<sup>5–7</sup> on the production of thyrotropin (TSH) in the fetal pars tuberalis (PT) and consequent TSH receptor-mediated effects on tanycytes lining ...