Blar i forfatter "Pettersen, Torkild"
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Improving and utilizing functional in vitro cAMP assay in pursuit to discover allosteric modulators of the GABAB receptor
Pettersen, Torkild (Mastergradsoppgave; Master thesis, 2021-07-05)The GABAergic system is the main inhibitory neuronal system utilized within the central nervous system (CNS). γ-aminobutyric acid (GABA) is the fundamental neurotransmitter which transmit inhibitory signals through GABA receptors, the ionotropic GABAA and GABAC receptors; and the metabotropic G-protein coupled receptor GABAB receptor. Disruption of this system is associated with a range of psychiatric ...