Blar i forfatter "Schäfer, Stephan Martin Gastón"

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    • A Phase 1b PK/PD Study to Demonstrate Antigen Elimination with RLYB212, a Monoclonal Anti-HPA-1a Antibody for FNAIT Prevention 

      Geisen, Christof; Fleck, Erika; Schäfer, Stephan Martin Gastón; Walter, Carmen; Braeuninger, Susanne; Jensen, Jens Søndergaard; Sheridan, Douglas; Patki, Kiran; Armstrong, Róisín; Skogen, Bjørn; Behrens, Frank; Seifried, Erhard; Kjeldsen-Kragh, Jens; Kjær, Mette; Köhm, Michaela (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-12)
      Background - Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a rare bleeding disorder of the fetus/newborn caused by development of maternal alloantibodies against fetal human platelet antigens (HPAs), predominantly HPA-1a. Currently there are no treatments available to prevent maternal alloimmunization to HPAs or FNAIT.<p> <p>Methods - This proof-of-concept study (EudraCT Number: ...