• Five-Year Risk of Cardiovascular Events after Transient Ischemic Attack: Results from a Prospective Cohort 

      Ildstad, Fredrik; Wethal, Torgeir; Ellekjær, Hanne; Lydersen, Stian; Mollnes, Tom Eirik; Ueland, Thor; Aukrust, Pål; Indredavik, Bent (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-10)
      Objectives. There are few contemporary, prospective studies reporting on the long-term risk of stroke and other cardiovascular (CV) events after transient ischemic attack (TIA). The primary aim was to examine the risk of new CV events within 5 years after TIA. The secondary aim was to identify baseline predictors of long-term CV events, including inflammatory biomarkers in a subgroup analysis. ...
    • Rationale and design of the PRevention of cArdiac Dysfunction during Adjuvant breast cancer therapy (PRADA II) trial: a randomized, placebo-controlled, multicenter trial 

      Mecinaj, Albulena; Gulati, Geeta; Heck, Siri Lagethon; Holte, Espen; Fagerland, Morten Wang; Larsen, Alf Inge; Blix, Egil Støre; Geisler, Jürgen; Wethal, Torgeir; Omland, Torbjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-27)
      Background - Recent advances in the treatment algorithms of early breast cancer have markedly improved overall survival. However, anthracycline- and trastuzumab-associated cardiotoxicity may lead to dose-reduction or halt in potentially life-saving adjuvant cancer therapy. Early initiated neurohormonal blockade may prevent or attenuate the cardiotoxicity-induced reduction in cardiac function, but ...