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Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38 MAPK-MK2 axis and affects NF-κB-mediated transcription
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-09)Steroid receptor coactivator-3 (SRC-3) regulates the activity of both nuclear hormone receptors and a number of key transcription factors. It is implicated in the regulation of cell proliferation, inflammation and in the progression of several common cancers including breast, colorectal and lung tumors. Phosphorylation is an important regulatory event controlling the activities of SRC-3. Serine 857 ... -
Neural network based country wise risk prediction of COVID-19
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-16)The recent worldwide outbreak of the novel coronavirus (COVID-19) has opened up new challenges to the research community. Artificial intelligence (AI) driven methods can be useful to predict the parameters, risks, and effects of such an epidemic. Such predictions can be helpful to control and prevent the spread of such diseases. The main challenges of applying AI is the small volume of data and the ... -
Lærere i nye roller som oversettere: Hvilket handlingsrom har de for utvikling?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-07)<p>This article contributes to considerations about the development of the teaching profession. The study focuses on teachers in new roles – teachers who practice in the school while also being responsible for school development in their subject field. The empirical material in this longitudinal study includes interviews with three groups of teachers; from the project Matematikk i nord (2007–2011), ... -
Soft thresholding schemes for multiple signal classification algorithm
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-28)Multiple signal classification algorithm (MUSICAL) exploits temporal fluctuations in fluorescence intensity to perform super-resolution microscopy by computing the value of a super-resolving indicator function across a fine sample grid. A key step in the algorithm is the separation of the measurements into signal and noise subspaces, based on a single user-specified parameter called the threshold. ... -
Deep Generative Models in Credit Scoring
(Doctoral thesis; Doktorgradsavhandling, 2021-02-05)Banks need to develop effective credit scoring models to better understand the relationship between customer information and the customer's ability to repay the loan. The output of such a model is called the default probability and is used to rank loan applications in terms of their creditworthiness. The focus of this thesis is to develop novel credit scoring methodologies that solve well-known ... -
Nurturing pedagogical praxis through deliberative communication
(Chapter; Bokkapittel, 2020)Previous research has identified a need to critically investigate the formative aspects of different teaching practices in light of the purpose of higher education to educate students’ with a capacity to act in a professionally responsible manner in preparation for the world of work. This chapter is a case study of one experienced academic developer (AD) who collaborates with an educational leader ... -
Iscenesatt ulikhet. Internasjonalt samarbeid i teaterutdanninger
(Chapter; Bokkapittel, 2019-09-17)Denne artikkelen tar utgangspunkt i et samarbeidsprosjekt mellom teaterutdanningene ved et russisk og et norsk universitet og diskuterer hvordan ulikhet og uenighet om teatertradisjoner og undervisningsfilosofi kan brukes som en ressurs. I diskusjonen benyttes teori om demokrati og utdanning og teori om uenighetsfellesskap. Erfaringene oppsummeres med at trygge rammer, fleksibilitet og vektlegging ... -
Drama og teater som tilnærming i aksjonsforskning - å øve på framtida.
(Chapter; Bokkapittel, 2020-12-23)In this chapter, we ask how drama and theatre can be a useful approach to action research processes. We focus on interventions, using teacher education as an arena for development. The empirical point of view is based on several research and developmental projects over years, together with two examples from recent developmental work. Our theoretical framework is based on theories of learning and ... -
Mangfoldsperspektiver i forskning på vold i nære relasjoner
(Chapter; Bokkapittel, 2020-06-10)Most research on domestic violence has focused on violence against women in a gender perspective. However, there has been an increasing understanding of the importance of other social dimensions in order to understand the nature and impact of the violence. The aim of this chapter is to explore the current status of research on domestic violence in a diversity perspective. We argue that dimensions like ... -
The 1st Agriculture-Vision Challenge: Methods and Results
(Chapter; Bokkapittel, 2020-07-28)The first Agriculture-Vision Challenge aims to encourage research in developing novel and effective algorithms for agricultural pattern recognition from aerial images, especially for the semantic segmentation task associated with our challenge dataset. Around 57 participating teams from various countries compete to achieve state-of-the-art in aerial agriculture semantic segmentation. The Agriculture-Vision ... -
Description of the uEMEP_v5 downscaling approach for the EMEP MSC-W chemistry transport model
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-11)A description of the new air quality downscaling model – the urban EMEP (uEMEP) and its combination with the EMEP MSC-W model (European Monitoring and Evaluation Programme Meteorological Synthesising Centre West) – is presented. uEMEP is based on well-known Gaussian modelling principles. The uniqueness of the system is in its combination with the EMEP MSC-W model and the “local fraction” calculation ... -
Plasmid Identification and Plasmid-Mediated Antimicrobial Gene Detection in Norwegian Isolates
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-27)Norway is known for being one of the countries with the lowest levels of antimicrobial resistance (AMR). AMR, through acquired genes located on transposons or conjugative plasmids, is the horizontal transmission of genes required for a given bacteria to withstand antibiotics. In this work, bioinformatic analysis of whole-genome sequences and hybrid assembled data from Escherichia coli, and Klebsiella ... -
Associations of accelerometer-determined physical activity and sedentary behavior with sarcopenia and incident falls over 12 months in community-dwelling Swedish older adults
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-05)<i>Objective</i>: To determine associations of accelerometer-determined time and bouts of sedentary behavior, light physical activity (PA) and moderate-to-vigorous PA (MVPA) with sarcopenia and incident falls over 12 months. <p> <p><i>Methods</i>:A total of 3334 Swedish 70-year-olds were assessed for sarcopenia, as defined by the revised definition of the European Working Group on Sarcopenia in ... -
Post-stroke health-related quality of life at 3 and 12 months and predictors of change in a Danish and Arctic Norwegian Region
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-30)Objectives: To investigate changes in health-related quality of life between 3- and 12-months post-stroke in a north Norwegian and a Danish region that organize their rehabilitation services differently, and to identify clinically relevant predictors of change. Design: Prospective multicentre cohort study. Subjects: In total, 304 patients with first-ever stroke (male sex 59%, mean age 68.7 years) ... -
Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-21)Structural features of proton-deficient heteroaromatic natural products, such as the breitfussins, can severely complicate their characterization by NMR spectroscopy. For the breitfussins in particular, the constitution of the five-membered oxazole central ring cannot be unequivocally established via conventional NMR methods when the 4′-position is halogenated. The level of difficulty is exacerbated ... -
Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-12)Non‐homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double‐strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J recombination to increase the repertoire of B and T cell receptors. DSBs are also generated during the class switch recombination (CSR) process in mature B lymphocytes, providing ... -
Time trends in the effects of mindfulness-based cognitive therapy for depression: A meta-analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-21)Recent studies suggest that the effects of cognitive therapies for depression show systematic changes over time. A meta‐analysis was conducted to explore the temporal development of the effect of mindfulness‐based cognitive therapy (MBCT) for current depression in studies that used the Beck Depression Inventory (BDI) or the Hamilton Depression Rating Scale (HDRS) as outcome measures. A systematic ... -
Cyberbullying status and mental health in Norwegian adolescents
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)The aim of the present study was to examine how the cyberbullying status (not involved, cyber‐victim only, cyberbully only, cyber‐victim and bully) is related to the mental health of the adolescents when controlled for traditional bullying experience. We also examined the potential moderator sex on the relationship between cyberbullying status and mental health. Univariate analyses of variance were ... -
The 9+ screening test score does not predict injuries in elite floorball players
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-05)We aimed to examine whether the 9+ screening test score could predict injuries in elite floorball players. Eighty‐four elite floorball players participated in the study. At baseline, two physiotherapists assessed the participants using the 9+ screening test. The test score reflects strength, stability, mobility, and functional movement pattern with an emphasis on the lower body and core. Injuries ... -
Recommendations for initial examination, differential diagnosis, and management of concussion and other head injuries in high-level football
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-17)Head injuries can result in substantially different outcomes, ranging from no detectable effect to transient functional impairments to life‐threatening structural lesions. In high‐level international football (soccer) tournaments, on average, one head injury occurs in every third match. Making the diagnosis and determining the severity of a head injury immediately on‐pitch or off‐field is a major ...