The snow crab (<i>Chionoecetes opilio</i>) is an invasive species new to the Barents Sea that expands its geographic range by larval drift and adult migration. To evaluate the potential spreading of the species in the Barents Sea, we investigated temperature selection and the final thermal preferendum (FTP) of nine adult males in a free choice horizontal temperature gradient (~ 1.0–5.5 °C) for 24 ...

<i>Background</i> - DNA methylation changes in peripheral blood have recently been identified in relation to lung cancer risk. Some of these changes have been suggested to mediate part of the effect of smoking on lung cancer. However, limitations with conventional mediation analyses mean that the causal nature of these methylation changes has yet to be fully elucidated.<p> <p><i>Methods</i> - We ...

Reglene om anke til lagmannsretten ble revidert da tvisteloven ble vedtatt i 2005, men mye tyder på at revisjonen ikke har virket helt etter hensikten. Reglene har flere ganger senere blitt foreslått endret. I denne artikkelen blir det argumentert for at det bør gjøres mer grunnleggende endringer av ankereglene enn det som hittil har blitt vurdert. Forfatterne hevder at de norske ankereglene i for ...

In mammals, melatonin is responsible for the synchronisation of seasonal cycles to the solar year. Melatonin is secreted by the pineal gland with a profile reflecting the duration of the night and acts via the pituitary pars tuberalis (PT), which in turn modulates hypothalamic thyroid hormone status via seasonal changes in the production of locally‐acting thyrotrophin. Recently, we demonstrated that, ...

<i>Objective:</i> - The chemokine CXCL16 (C-X-C motif ligand 16) is a scavenger receptor for OxLDL (oxidized low-density lipoproteins) and involved in inflammation at sites of atherosclerosis. This study aimed to investigate the association of CXCL16 with clinical outcome in patients with acute coronary syndrome.<p> <p><i>Approach and Results:</i> - Serial measurements of CXCL16 were performed ...

<i>Background</i> - In different models of hypoxia, blockade of opioid or N-methyl-D-aspartate (NMDA) receptors shows cardio- and neuroprotective effects with a consequent increase in animal survival. The aim of the study was to investigate effects of pre-treatment with Morphine or Ketamine on hemodynamic, acid-base status, early survival, and biochemical markers of brain damage in a rat model of ...

<i>Background</i> - Symptoms of anxiety and depression are common mental health problems in children and are often referred to as internalizing symptoms. Youth with such symptoms are at greater risk for poor academic achievement, school non-completion, and future mental health problems, all of which, lead to public health consequences and costs to society. The aim of the current study was to ...

This chapter discusses first the value of enshrining children’s rights in national Constitutions in addition to implementing the United Nations Convention of the Rights of the Child. Second, it gives a brief introduction to the Nordic countries, their societies and legal systems, such as the Nordic welfare model, court systems and the sources of law. An introduction is also given to Nordic constitutional ...

The prometastatic stroma generated through tumor cells/host cells interaction is critical for metastatic growth. To elucidate the role of ICAM-1 on the crosstalk between tumor and primary liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), implicated in tumor adhesion and angiogenesis, we performed <i>in vitro</i> cocultures and an <i>in vivo</i> model of liver metastasis ...

Autophagosome formation depends on a carefully orchestrated interplay between membrane-associated protein complexes. Initiation of macroautophagy/autophagy is mediated by the ULK1 (unc-51 like autophagy activating kinase 1) protein kinase complex and the autophagy-specific class III phosphatidylinositol 3-kinase complex I (PtdIns3K-C1). The latter contains PIK3C3/VPS34, PIK3R4/VPS15, BECN1/Beclin 1 ...