Although great progress has been made in the fine-tuning of diplotypes, there is still a need to further improve the predictability of individual phenotypes of pharmacogenetically relevant enzymes. The aim of this study was to analyze the additional contribution of sex and variants identified by exome chip analysis to the metabolic ratio of five probe drugs. A cocktail study applying dextromethorphan, ...

A number of tourists visit churches on their holiday without being religious or having any religious motivation. If religion is not important for the visit, what is then central to the tourist experience, and how do tourists describe their church visit? In this article, I examine tourists’ church visits and the meaning it gives. In a setting characterized through tourism and religion, and with ...

Several studies have noted that the International Seabed Authority (ISA) scores low on public participation. However, none have studied the efforts of non-governmental organizations to exert influence on the ISA’s rulemaking processes. I examine how environmental NGOs and private mining contractors attempt to sway one narrow, but existential, part of the ISA’s draft exploitation regulations between ...

A good and accessible biomarker is of great clinical value in neuroendocrine tumor (NET) patients, especially considering its frequently indolent nature and long-term follow-up. Plasma chromogranin A (CgA) and 5-hydroxyindoleacetic acid (5-HIAA) are currently used as biomarkers in NET, but their sensitivity and specificity are restricted. 5-HIAA is the main metabolite of serotonin, an important ...

Teacher Education (TE) in Norway has developed with a strong emphasis on the research-based and practice-oriented professionalization of TE programs led by universities and university colleges. In the past decade, national reforms have emphasized the development of research competence for student teachers, enabling them to continually develop their own and the school’s collective practices. Center ...

In this paper, we introduce some new weighted maximal operators of the Fejér means of the Walsh–Fourier series. We prove that for some “optimal” weights, these new operators indeed are bounded from the martingale Hardy space H_p(G)to the Lebesgue space L_p(G), for 0 < p < 1/2. Moreover, we also prove sharpness of this result. As a consequence, we obtain some new and well-known ...

In the summer of 2020, ESA changed the orbit of CryoSat-2 to align periodically with NASA's ICESat-2 mission, a campaign known as CRYO2ICE, which allows for near-coincident CryoSat-2 and ICESat-2 observations in space and time over the Arctic until summer 2022, where the CRYO2ICE Antarctic campaign was initiated. This study investigates the Arctic CRYO2ICE radar and laser freeboards acquired by ...

A singular <i>k</i>-tuple of a tensor T of format (<i>n₁</i>, ..., <i>n</i>_<i><k></i>) is essentially a complex critical point of the distance function from <i>T</i> constrained to the cone of tensors of format (<i>n</i>₁, ..., <i>n_k</i>) of rank at most one. A generic tensor has finitely many complex singular <i>k</i>-tuples, and their number depends only ...

Purpose Group B streptococcus (GBS) colonizes the gastrointestinal and vaginal mucosa in healthy adults, but has also become an increasing cause of invasive infection. The aims of this study were to describe the incidence and factors associated with the occurrence of invasive GBS disease in adults in Norway. Methods We performed a nationwide retrospective case–control study of invasive GBS infections ...

Bygg- og anleggsbransjen utgjør en svært risikabel arbeidsplass, noe som gjenspeiler seg i omfanget av arbeidsulykker. Av berørte parter er utenlandske, og spesielt polske arbeidere, overrepresentert på skadestatistikken i forbindelse med de mest alvorlige arbeidsulykkene (Mostue et al., 2022). For å sikre en trygg arbeidsplass for alle aktører anses det som nødvendig å drive kontinuerlig ...