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Sykepleieres opplevelser av utfordrende atferd og voldsepisoder hos pasienter med demens i skjermede sykehjemsavdelinger
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-08)Bakgrunn: Sykepleiere i skjermede sykehjemsavdelinger skårer høyt på stress og emosjonelle krav. De opplever mer vold, trusler og uønsket seksuell oppmerksomhet fra pasienter enn andre yrkesutøvere. <p> <p>Hensikten: med denne studien er å belyse faktorer som sykepleierne opplever som emosjonelt belastende relatert til utfordrende atferd hos pasienter med demens i skjermede sykehjemsavdelinger, ... -
The novel bacteriocin romsacin from Staphylococcus haemolyticus inhibits Gram-positive WHO priority pathogens
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-31)Staphylococcus haemolyticus is an increasingly relevant nosocomial pathogen. The combination of multi-drug resistance and ability to form biofilms makes S. haemolyticus infections difficult to treat. Bacteriocins are ribosomally synthesized antimicrobial peptides produced by bacteria to inhibit growth of often closely related bacteria. Due to differences in the modes of action between bacteriocins ... -
Helsepersonells prevensjonsveiledning – en kvalitativ studie av unge kvinners erfaringer med prevesjonsveiledning og valg av prevensjonsmiddel
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-01)En stor andel unge kvinner i Norge bruker prevensjon og har oppsøkt helsepersonell for å få prevensjonsveiledning og resept på prevensjonsmidler. På tross av dette er det utført lite forskning i Norge som undersøker kvinners erfaringer med prevensjonsveiledning, og hva som påvirker deres valg av prevensjonsmiddel. Hensikten med studien var å få kunnskap om hvilke erfaringer unge kvinner har med å ... -
Beliefs about mental health in incarcerated males: a qualitative interview study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-14)Introduction: Beliefs about mental health are shaped by the sociocultural context. Prisons have unique environmental and social features, and the prevalence of mental health problems in incarcerated populations is exceptionally high. These features make prisons especially interesting settings for exploring health beliefs. The aim of this study was to explore the conceptualizations of mental health ... -
Optical Constituent Concentrations and Uncertainties Obtained for Case 1 and 2 Waters From a Spectral Deconvolution Model Applied to In Situ IOPs and Radiometry
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-01)A spectral deconvolution model (SDM) for inversion of light absorption, a(λ) and backscattering, bb(λ), to estimate concentrations of chlorophyll (CHL), colored dissolved organic material (CDOM) and non-biogenic mineral suspended solids (MSS) in offshore and shelf waters is presented. This approach exploits the spectral information embedded in the ratio bb(λ)/a(λ), without the need to know each ... -
Cognitive Neuroscience Perspectives on Language Acquisition and Processing
(Journal article; Tidsskriftartikkel, 2023-11-21)<p>The earliest investigations of the neural implementation of language started with examining patients with various types of disorders and underlying brain damage. The advent of neuroimaging tools in the twentieth century drastically changed the landscape of the field of the (cognitive) neuroscience of language, expanding the variety and depth of research questions one could ask without being ... -
Comprehensive Analysis of Solar Panel Performance and Correlations with Meteorological Parameters
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-08)To mitigate the adverse effects of fossil fuel-based energy, mankind is in constant search of clean and cost-effective sources of energy, such as solar energy. The economic viability of a power plant to harness solar energy mostly depends on the efficiency of solar panels. Investigations over the years show that the solar panel efficiency significantly depends on the different meteorological parameters. ... -
Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-24)Background - A new Chronic Kidney Disease Epidemiology Collaboration equation without the race variable has been recently proposed (CKD-EPIAS). This equation has neither been validated outside USA nor compared with the new European Kidney Function Consortium (EKFC) and Lund-Malmö Revised (LMREV) equations, developed in European cohorts.<p> <p>Methods - Standardized creatinine and measured glomerular ... -
C1 inhibitor deficiency enhances contact pathway–mediated activation of coagulation and venous thrombosis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-11)C1 inhibitor (C1INH) is a multifunctional serine protease inhibitor that functions as a major negative regulator of several biological pathways, including the contact pathway of blood coagulation. In humans, congenital C1INH deficiency results in a rare episodic bradykinin-mediated swelling disorder called hereditary angioedema (HAE). Patients with C1INH deficiency–associated HAE (C1INH-HAE) have ... -
Local management of the COVID-19 pandemic in Norway: a longitudinal interview study of municipality chief medical officers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-12)Objective - To explore the experiences and views of Norwegian Municipality Chief Medical Officers (MCMOs) on preparedness, collaboration, and organization during the COVID-19 pandemic to gain insight into local crisis management of value for future pandemic responses.<p> <p>Design - Longitudinal qualitative interview study. We conducted semi-structured digital interviews with nine MCMOs working ... -
Prognostic factors and independent validation of a risk stratification model in octogenarian patients irradiated for brain metastases
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-25)Background/Aim: This study aimed at validation of a prognostic model, originally developed by Rades et al., in an age-restricted, particularly vulnerable subgroup of patients with brain metastases, because international variations in clinical practice and survival outcomes may impact on the performance of survival prediction tools. Patients and Methods: Retrospectively, data from a single institution ... -
Independent validation of a risk stratification model predicting survival in elderly patients irradiated for bone metastases
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02)Background/Aim: Many patients with bone metastases receive palliative radiotherapy. However, treatment personalization tools are needed, due to heterogeneous survival. The aim of this study was to analyze the validity of the prognostic survival model, originally developed by Rades et al., because international variations in clinical practice and survival outcomes may impact on the performance of ... -
The LabPS score: Inexpensive, Fast, and Site-agnostic Survival Prediction
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04)Objectives: To provide a widely applicable, blood-biomarker-based and performance-status-based prognostic model, which predicts the survival of patients undergoing palliative non-brain radiotherapy. This model has already been examined in a cohort of patients treated for brain metastases and performed well.<p> <p>Methods: This was a retrospective single-institution analysis of 375 patients, ... -
Patterns of Care and Survival in Cancer Patients with Brain Metastases Receiving Immune Checkpoint Inhibitors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-15)Introduction: Immune checkpoint inhibitors (ICIs) have become a mainstay of treatment for different cancer types. The purpose of this study was to evaluate patterns of care and overall survival (OS) after diagnosis of brain metastases in patients managed with ICI as component of care. Methods: This was a retrospective cohort study. Fifty patients were included (34 with brain metastases at first ... -
Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-01)Background - von Willebrand factor (VWF) and its cleaving protease, ADAMTS-13, form a pivotal axis that regulates hemostasis. However, the role of the VWF-ADAMTS-13 axis in the risk of future venous thromboembolism (VTE) is unknown.<p> <p>Objectives - To investigate whether plasma ADAMTS-13 levels and an imbalance with VWF levels, assessed as the VWF/ADAMTS-13 ratio, are associated with the risk ... -
Complement factors B, D, C3bBbP and risk of future venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-07)The complement system appears to be involved in the pathogenesis of venous thromboembolism (VTE).<p> <p>We investigated the association of complement factors (CF) B, D, and the alternative pathway convertase, C3bBbP, measured at inclusion, with the risk of future VTE in a nested case-control study; 380 VTE patients and 804 age- and sex-matched controls derived from the Tromsø study. Odds ratios ... -
‘PISA effects’ on Norwegian education. A critical realist perspective
(Doctoral thesis; Doktorgradsavhandling, 2024-02-09)<p>The objective of the thesis is to examine, from a critical realist perspective and by using Margaret Archer’s conceptual framework, possible effects that the Programme for International Student Assessment (PISA) test has on the Norwegian education system and on school personnel. The intention has been to reconceptualise the notion of ‘PISA effects’ both at the systemic (macro) and individual ... -
PISA and Teachers’ Reflexivities. A Mixed Methods Case Study
(Journal article; Tidsskriftartikkel, 2024-01-12)Neoliberal educational reforms include extensive use of standardized tests. We examine the Program for International Student Assessment (PISA) initiated and developed by the Organization for Economic Cooperation and Development (OECD). Examining previous research on teachers’ reactions to neoliberal reforms altering their work context, we have identified three theoretical frameworks in use: labour ... -
Psychoactive substances and previous hospital admissions, triage and length of stay in rural injuries: a prospective observational study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-27)Background - Patients admitted to hospital after an injury are often found to have used psychoactive substances prior to the injury. The aim of this study was to investigate the associations between psychoactive substances (alcohol, psychoactive medicinal drugs and illicit drugs) and previous hospital admissions, triage and length of stay in the arctic Norwegian county of Finnmark.<p> <p>Methods ... -
CSF, Blood, and MRI Biomarkers in Skogholt’s Disease—A Rare Neurodegenerative Disease in a Norwegian Kindred
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-26)Skogholt’s disease is a rare neurological disorder that is only observed in a small Norwegian kindred. It typically manifests in adulthood with uncharacteristic neurological symptoms from both the peripheral and central nervous systems. The etiology of the observed cerebral white matter lesions and peripheral myelin pathology is unclear. Increased cerebrospinal fluid (CSF) concentrations of protein ...
