This thesis explores the prospect of a waveguide device for optical trapping and Raman spectroscopy of single biological nanoparticles. The aim of the work is to develop a Raman-on-chip device capable of training and measuring single particles in individual trapping sites, such that the throughput of the device can be increased through parallelization. The challenge posed by the induced Raman ...

Purpose - The purpose of the present study was to investigate the health and exercise performance effects of street football training on very small pitches surrounded by boards in young habitually active men in comparison to small-sided football training on grass.<p> <p>Methods - Thirty-nine habitually active men (30.7 ± 6.7 years, 90.9 ± 16.6 kg, 183.8 ± 4.5 cm, 39.6 ± 6.0 mL/min/kg) were randomly ...

Norwegian work on microdata started out with the full count 1801 census and census and vital records from around the capital. Today, most census and ministerial records from 1801 until the mid-20th century have been scanned, transcriptions are being completed, much is encoded and made available via the websites of the Digital National Archives and UiT The Arctic University of Norway. This article ...

Spam emails pose a substantial cybersecurity danger, necessitating accurate classification to reduce unwanted messages and mitigate risks. This study focuses on enhancing spam email classification accuracy using stacking ensemble machine learning techniques.We trained and tested five classifiers: logistic regression, decision tree, K-nearest neighbors (KNN), Gaussian naive Bayes and AdaBoost. To ...

<p>Super-resolution optical microscopy (SRM) holds great promise for the advancement of life sciences, unlocking the secrets of the minute machinery composing living organisms. While broadly accepted in cell biology, the existing SRM methods haven’t effectively breached relevant fields such as histological practice, mainly due to the complexity, elevated costs, limited throughput, and incompatibility ...

INTRODUCTION - Our main objective was to investigate whether retinal neurodegeneration, estimated from lower thickness of inner retinal layers, was associated with incident all-cause dementia and Alzheimer's disease (AD).<p> <p>METHODS - We performed an individual participant data meta-analysis using unpublished data from four prospective cohort studies with a total of 69,955 participants (n = ...

Introduction - Insights into real-world treatment of atopic dermatitis (AD) are relevant to clinical decision making. The aim of this analysis was to characterize patients who receive dupilumab for AD in a real-world setting.<p> <p>Methods - The GLOBOSTAD registry is an ongoing, longitudinal, prospective, observational study of patients with AD who receive dupilumab according to country-specific ...

Venous thromboembolism (VTE) is a leading cause of preventable deaths in hospitals, and its incidence is not decreasing despite extensive efforts in clinical and laboratory research. Venous thrombi are primarily formed in the valve pockets of deep veins, where activated monocytes play a crucial role in bridging innate immune activation and hemostatic pathways through the production of inflammatory ...

Limb-girdle muscular dystrophy R9 (LGMDR9) is a progressive and disabling genetic muscle disease. Sleep is relevant in the patient care as it impacts on health, functioning, and well-being. LGMDR9 may potentially afect sleep by physical or emotional symptoms, myalgia, or sleep-disordered breathing (SDB) through cardiorespiratory involvement. The objective was to investigate the occurrence of ...

Background Reirradiation is a potentially useful option for many patients with recurrent cancer, aiming at cure or symptom palliation, depending on disease/recurrence type and stage. The purpose of this follow-up study to a previous review from 2016 was to summarize all recently published randomized trials. Points of interest again included identifcation of methodological strengths and weaknesses, ...