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Deciphering human cell type enriched transcriptomes across tissue types and the functional study of the endothelial enriched protein KANK3
(Doctoral thesis; Doktorgradsavhandling, 2023-11-13)The identification of cell type-specific genes and their modification under certain conditions is essential for our understanding of the human body. Such knowledge also allows us to study the function of uncharacterised genes in the correct cell type. Single-cell RNA sequencing (scRNAseq) can be used to profile different cell types, but cell removal and processing can introduce artifacts. In the ... -
Introduction: Research, Education, and Self-Determination in Sámi and Indigenous Journalism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022)This article advances the critical importance of Indigenous journalism – both as a field and practice – for Indigenous peoples’ right to self-determination. The co-authors demonstrate this through discussions of education, scholarship, and dissemination. We begin with a review of the current state of Indigenous journalism education while making a strong case for the continued development and advancement ... -
An Integrative Taxonomic Survey of Benthic Foraminiferal Species (Protista, Rhizaria) from the Eastern Clarion-Clipperton Zone
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-24)The abyssal Pacific Clarion Clipperton Zone (CCZ) hosts vast, commercially valuable seafloor deposits of polymetallic nodules. Foraminifera (testate protists) dominate benthic communities in this region. Here, we present a taxonomic survey, combining morphological and genetic data and focussing on mainly meiofauna-sized Foraminifera from the eastern CCZ. Sequences obtained from >100 specimens, the ... -
Interactive effects of ocean acidification and temperature on oxygen uptake rates in Calanus hyperboreus nauplii
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-26)The Arctic region is undergoing rapid and significant changes, characterized by high rates of acidification and warming. These transformations prompt critical questions about the resilience of marine communities in the face of environmental change. In the Arctic, marine zooplankton and in particular calanoid copepods play a vital role in the food web. Changes in environmental conditions could ... -
Role of grandparents in risky health behavior transmission: A study on smoking behavior in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-22)Exploring the role of grandparents in the intergenerational transmission of risky health behaviors, specifically smoking, this study aims to examine the differential influence of maternal and paternal grandparents on their grandchildren's smoking behavior in adulthood. Utilizing the Tromsø Study's unique three-generational dataset from Tromsø, Norway, we employ a control function approach. The ... -
Barents-2.5km v2.0: an operational data-assimilative coupled ocean and sea ice ensemble prediction model for the Barents Sea and Svalbard
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-22)An operational ocean and sea ice forecast model, Barents-2.5, is implemented for short-term forecasting at the coast off northern Norway, the Barents Sea, and the waters around Svalbard. Primary forecast parameters are sea ice concentration (SIC), sea surface temperature (SST), and ocean currents. The model also provides input data for drift modeling of pollutants, icebergs, and search-and-rescue ... -
Prevalence of malnutrition among older adults in a population-based study - The HUNT Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-19)Background Malnutrition is common in older adults and is associated with increased morbidity and mortality rates. Aim The aim of the study is to describe the prevalence of malnutrition based on low BMI, involuntary weight loss, and reduced food intake, in a Norwegian population of community-dwelling older adults and older adults living in nursing homes. Methods This population-based study ... -
Evaluation of meso- and microplastic ingestion by the northern fulmar through a non-lethal sampling method
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-11)An increasing number of organisms from the polar regions are reported contaminated by plastic. Rarely a nonkilling sampling method is used. In this study we wanted to assess plastic levels using stomach flushing and evaluate the method suitability for further research and monitoring. The stomach of 22 fulmars from Bjørnøya, Svalbard, were flushed with water in the field. On return to the laboratory, ... -
Copepods’ true colors: astaxanthin pigmentation as an indicator of fitness
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-08)Pigmentation is often overlooked in zooplankton, since these organisms are mostly colorless to fit the translucid water medium. However, one of the dominant zooplankton taxa in aquatic ecosystems—copepods—often show a bright red-orange or blue coloration owing to the accumulation of carotenoid pigments in some parts of their bodies. Even though there are many functional traits describing copepod’s ... -
Meaning of wellness in caring science based on Rodgers's evolutionary concept analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-28)Background: Wellness is a holistic, multidimensional, and process-oriented property on a continuum. It has been used interchangeably with and is undifferentiated from concepts such as health and well-being without an in-depth clarification of its theoretical foundations and a reflection on its meaning. The concept of wellness is frequently used, but its definition remains unclear.<p> <p>Aim: To ... -
Loss of species and genetic diversity during colonization: Insights from acanthocephalan parasites in northern European seals
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-19)Studies on host–parasite systems that have experienced distributional shifts, range fragmentation, and population declines in the past can provide information regarding how parasite community richness and genetic diversity will change as a result of anthropogenic environmental changes in the future. Here, we studied how sequential postglacial colonization, shifts in habitat, and reduced host ... -
Validation of forearm fracture diagnoses in administrative patient registers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-24)Summary The validity of forearm fracture diagnoses recorded in fve Norwegian hospitals was investigated using image reports and medical records as gold standard. A relatively high completeness and correctness of the diagnoses was found. Algorithms used to defne forearm fractures in administrative data should depend on study purpose.<p> <p>Purpose In Norway, forearm fractures are routinely recorded ... -
Early screening outcomes before, during, and after a randomized controlled trial with digital breast tomosynthesis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-01)Purpose: To describe and compare early screening outcomes before, during and after a randomized controlled trial with digital breast tomosynthesis (DBT) including synthetic 2D mammography versus standard digital mammography (DM) (To-Be 1) and a follow-up cohort study using DBT (To-Be 2). <p><p>Methods: Retrospective results of 125,020 screening examinations from four consecutive screening rounds ... -
Effect of Pharmacological Treatment of Attention-Deficit/Hyperactivity Disorder on Criminality
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-27)Objective: Criminality rates are higher among persons with attention-deficit/hyperactivity disorder (ADHD), and evidence that medication reduces crime is limited. Medication rates between clinics vary widely even within universal health care systems, partly because of providers’ treatment preferences. We used this variation to estimate causal effects of pharmacological treatment of ADHD on 4-year ... -
Effect of ADHD medication on risk of injuries: a preference-based instrumental variable analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-24)ADHD is associated with an increased risk of injury. Causal evidence for efects of pharmacological treatment on injuries is scarce. We estimated efects of ADHD medication on injuries using variation in provider preference as an instrumental variable (IV). Using Norwegian registry data, we followed 8051 patients who were diagnosed with ADHD aged 5 to 18 between 2009 and 2011 and recorded their ADHD ... -
Tromsø dialect
(Master thesis; Mastergradsoppgave, 1989-09)The Tromsø dialect situation today is probably typical of many Northern Norwegian town dialects. It has developed from an old local non-standard speech variety which was very similar to the present local rural dialects. What clearly distinguishes the modern town version, as spoken by young people today, from the old one, however, is the inclusion of a significant number of bokmål features. This study ... -
Myfood24 på norsk: et selvadministrert digitalt 24-timers kostintervju
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-16)Innen ernæringsepidemiologien er vi i stor grad avhengige av å estimere inntak av mat og næringsstoffer basert på selvrapportering, til tross for at denne tilnærmingen er beheftet med målefeil. Graden av målefeil har betydning for analyser og tolkning av resultater, så metodene vi bruker bør være så valide som mulig. Å utvikle brukervennlige kostholdsmetoder som reduserer belastning for deltaker kan ... -
Change in Climate Sensitivity and Its Dependence on the Lapse-Rate Feedback in 4 x CO2 Climate Model Experiments
(Journal article; Tidsskriftartikkel, 2022-04-19)Robust estimates of climate sensitivity are important for decision-making on mitigation of climate change. However, climate sensitivity and its governing processes are still subject to large uncertainty. Recently it has been established that climate sensitivity changes over time in numerical climate model experiments with abrupt quadrupling of the CO<sub>2</sub> concentration. Here we conduct an ... -
Kunnskapsoverføring i beredskapsorganisasjoner i Longyeabyen, Svalbard - En kvalitativ studie av forvaltningen av taus kunnskap i beredskapsorganisasjoner preget av høy turnover
(Master thesis; Mastergradsoppgave, 2023-07-13)Svalbard er et lite arktisk øysamfunn som betegnes som et rotasjonssamfunn. Høy turnover av ansatte i Longyearbyens beredskapsorganisasjoner har gjentatte ganger blitt fremhevet som en utfordring for erfarings- og kunnskapsoverføring (DSB, 2016), og for kontinuiteten i arbeidet med samfunnssikkerhet- og beredskap. Etter det fatale snøskredet i 2015 ble etablering av en systematikk som ivaretar ... -
Felles situasjonsforståelse og styring under kriser
(Master thesis; Mastergradsoppgave, 2023-06-30)Natt til 30.desember 2020 gikk det et kvikkleireskred i Gjerdrum og en lang og krevende redningsaksjon ble satt i gang. Redningsaksjonen involverte en rekke aktører, både offentlige, private og frivillige organisasjoner. Samvirke er et sentralt begrep i slike redningsaksjoner. Kvikkleireskredet på Gjerdrum viste hvordan det norske beredskapssamvirket fungerer på sitt beste. I tillegg til et godt ...