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Use of health and dental care services in adults with intellectual disability in relation to age and intellectual disability levels
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-18)Background - This study investigates the use of health and dental care services in adults with intellectual disability in the last 12 months according to Norwegian recommendations and in relation to age and intellectual disability levels.<p> <p>Method - A cross-sectional community-based survey including 214 participants (56% men). POMONA health indicators were used for data collection.<p> <p>Results ... -
Clash of Identities: Ontological (In)Securities of Afghanistan and Pakistan, and the Repercussions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-16)The notion of security denotes freedom from threats. Ontological security implies emancipation from threats to core values that identify a person or a state. This article demonstrates the Pak-Afghan relationship as a case in point. It offers a relatively new perspective for understanding the continued contentious relationship between Afghanistan and Pakistan. It argues that the Pashtun state ... -
The European Union's responses to the COVID-19 crisis: How to fight a pandemic with the internal market
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)In a liberalized market economy, states tend to purchase supplies required for producing publicly funded services, such as healthcare, from the markets instead of producing them themselves. The availability of critical supplies thus becomes a question of supply-side availability and supply chain management, and therefore their availability is conceptualized in terms of security of supply. The European ... -
Cigarette Smoking and Endometrial Cancer Risk: Observational and Mendelian Randomization Analyses
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-16)Background: Current epidemiologic evidence indicates that smoking is associated with a lower endometrial cancer risk. However, it is unknown if this association is causal or confounded. To further elucidate the role of smoking in endometrial cancer risk, we conducted complementary observational and Mendelian randomization (MR) analyses.<p> <p>Methods: The observational analyses included 286,415 ... -
Ten-year tenure as a physician CEO at a Nordic university hospital: Five lessons learnt
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-21)Background - I was a 42-year-old neurosurgeon with experience as department head when I took chair as chief executive officer (CEO) at the University Hospital of North Norway to lead a comprehensive organisational and financial restructuring. This article aims to develop lessons learnt during my 10-year tenure.<p> <p>Methods - I restructured the organisation and hired a new executive team. We ... -
Veien videre for samisk reiseliv og kreative næringer
(Research report; Forskningsrapport, 2022)Hvordan kan en tettere sammenkobling mellom samiske kreative næringer og reiseliv bidra til nytenking om bærekraft, innovasjon og formidling av samisk kunnskap om natur og kultur – og slik bidra til utvikling av mat- og kulturopplevelser som gagner mangfoldet i Sápmi. -
Homesteading in the Arctic: The Logic Behind, and Prospects for, Russia’s ’Hectare in the Arctic’ Program
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022)Moscow launched its “Hectare in the Arctic” program in summer 2021, allowing Russian nationals to obtain a free hectare of land in the country’s northern regions. This plan is the latest attempt to address the chronic problem of outmigration and to attract new settlers to the Russian Arctic. Yet, multiple obstacles stand in the way of making the scheme a viable demographic solution. The primary ... -
Corrigendum to “Clinical reasoning in traditional medicine exemplified by the clinical encounter of Korean medicine” [Integr Med Res 2021: 10; 100641]
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-22)The authors regret that the funding number was incorrectly published in the above article. It is now reproduced correctly below. The authors would like to apologize for any inconvenience caused. -
Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-01)Bacterial and mitochondrial DNA, sharing an evolutionary origin, act as danger-associated molecular patterns in infectious and sterile inflammation. They both contain immunomodulatory CpG motifs. Interactions between CpG motifs and the complement system are sparsely described, and mechanisms of complement activation by CpG remain unclear. Lepirudin-anticoagulated human whole blood and plasma were ... -
Cohort profile: the Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) - a national research and quality registry with a biomaterial collection
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-08)Purpose - The Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) was established to harmonise and improve the quality of diagnostic practice across clinics assessing persons with cognitive symptoms in Norwegian specialist healthcare units and to establish a large research cohort with extensive clinical data.<p> <p>Participants - The registry recruits patients who are referred ... -
Kjønnsstratifiserte analyser i norske behandlingsstudier: en systematisk kartleggingsoversikt
(Research report; Forskningsrapport, 2022)Biologisk kjønn har betydning for kliniske utfall, og kunnskap om kjønnsforskjeller i behandlingsutfall kan bidra til sikrere og mer tilpasset behandling for pasienter. Hensikten med denne kartleggingsoversikten var å undersøke bruken av kjønnsstratifiserte analyser i studier på effekt av behandling i en norsk sammenheng.<p> <p>Vi utførte en kartleggingsoversikt. Det er en type kunnskapsoppsummering ... -
Impulse-driven oscillations of the near-Earth's magnetosphere
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-09)It is argued that a simple model based on magnetic image arguments suffices to give a convincing insight into both the basic static as well as some transient dynamic properties of the near-Earth's magnetosphere, particularly accounting for damped oscillations being excited in response to impulsive perturbations. The parameter variations of the frequency are given. Qualitative results can also be ... -
Nasjonale og regionale melde- og varselordninger for uønskede hendelser i pasientbehandlingen: systematisk oversikt
(Research report; Forskningsrapport, 2022)Alle virksomheter som yter helse- og omsorgstjenester skal arbeide systematisk for å redusere risiko for pasientskade som følge av tjenesteytelsen eller mangel på ytelse. Likevel oppstår uønskede hendelser av varierende alvorlighetsgrad. Anslagsvis rammer uønskede hendelser én av ti pasienter i norske sykehus. Norske virksomheter som yter helse- og omsorgstjenester plikter å varsle om alvorlige ... -
Samisk: láibi og gáhkku
(Conference object; Konferansebidrag, 2022) -
Utvalgt forskning om melde- og varselordninger i helse- og omsorgstje-nesten: forenklet metodevurdering – kartlegging
(Research report; Forskningsrapport, 2022-10)En nylig utført systematisk oversikt viste at det ikke finnes forskning som har undersøkt effekten av nasjonale og regionale, generelle melde- og varselordninger på alvorlige hendelser i helse- og omsorgstjenesten. Derfor var det hensiktsmessig å undersøke forskning som har sett på tilgrensende problemstillinger.<p> <p>Formålet med dette arbeidet var å kartlegge studier om mulige sammenhenger ... -
Association of Klotho protein levels and KL-VS heterozygosity with Alzheimer disease and amyloid and tau burden
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-22)Importance Identification of proteins and genetic factors that reduce Alzheimer disease (AD) pathology is of importance when searching for novel AD treatments. Heterozygosity of the KL-VS haplotype has been associated with reduced amyloid and tau burden. Whether this association is mediated by the Klotho protein remains unclear. Objectives To assess concentrations of Klotho in cerebrospinal ... -
Longitudinal Predictors of Listening Comprehension in Bilingual Primary School-Aged Children
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-17)Research on monolingual children has shown that listening comprehension is predicted by a range of language and cognitive skills; less is known about predictors of listening comprehension in bilingual children and about the role of language input. This study presents longitudinal data on predictors of English listening comprehension in 100 bilingual children between the ages of 5;8 and 6;8 years. ... -
Circulating Isovalerylcarnitine and Lung Cancer Risk: Evidence from Mendelian Randomization and Prediagnostic Blood Measurements
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-04)Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies.<p> <p>Materials and Methods: We used Mendelian randomization (MR) to screen 207 metabolites for their role in lung cancer predisposition using independent genome-wide association studies (GWAS) of blood ... -
Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)<p><b> Background:</b> The effect of a fourth dose of COVID-19 vaccine on the risk of death in the oldest and frailest individuals is unknown. <p><b> Methods</b> Two matched cohorts were formed using Swedish nationwide registers. In the first, residents of long-term care facilities (LTCFs) given a fourth dose of an mRNA vaccine from 1 January 2022 onwards were matched 1:1 on birth year and ... -
Sex differences in arterial hypertension
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-22)There is strong evidence that sex chromosomes and sex hormones influence blood pressure (BP) regulation, distribution of cardiovascular (CV) risk factors and co-morbidities differentially in females and males with essential arterial hypertension. The risk for CV disease increases at a lower BP level in females than in males, suggesting that sex-specific thresholds for diagnosis of hypertension may ...
