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dc.contributor.authorHalvorsen, Kjell H.
dc.contributor.authorLandmark, Cecilie Johannessen
dc.contributor.authorGranås, Anne Gerd
dc.date.accessioned2017-02-15T09:35:24Z
dc.date.available2017-02-15T09:35:24Z
dc.date.issued2016-06
dc.description.abstractIntroduction. Antiepileptic drugs (AEDs) are used to treat different conditions in elderly patients and are among the drug classes most susceptible to be involved in drug-drug interactions (DDI). The aim of the study was to describe and compare use of AEDs between home care service and nursing home patients, as these patients are not included in nationwide databases of drug utilization. In the combined population, we investigate DDI of AEDs with other central nervous system- (CNS-) active drugs and DDIs involving AEDs in general. Materials and Methods. Point-prevalence study of Norwegian patients in home care services and nursing homes in 2009. At the patient level, we screened for different DDIs involving AEDs. Results. In total, 882 patients (7.8%) of 11,254 patients used AEDs and number of users did not differ between home care services and nursing homes (8.2% versus 7.7%). In the combined population, we identified 436 potential DDIs in 45% of the patients. Conclusions. In a large population of elderly, home care service and nursing home patients do not differ with respect to exposure of AEDs but use more AEDs as compared to the general population of similar age. The risk of DDIs with AEDs and other CNS-active drugs should be taken into consideration and individual clinical evaluations are assessed in this population.en_US
dc.descriptionPublished version, source at: <a href=http://dx.doi.org/10.1155/2016/5153093>http://dx.doi.org/10.1155/2016/5153093</a>en_US
dc.identifier.cristinIDFRIDAID 1374902
dc.identifier.doi10.1155/2016/5153093
dc.identifier.issn2090-1348
dc.identifier.issn2090-1356
dc.identifier.urihttps://hdl.handle.net/10037/10298
dc.language.isoengen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.journalEpilepsy Research and Treatment
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710en_US
dc.subjectVDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710en_US
dc.titlePrevalence of Different Combinations of Antiepileptic Drugs and CNS Drugs in Elderly Home Care Service and Nursing Home Patients in Norwayen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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