Show simple item record

dc.contributor.authorO'Doherty, Mark G.
dc.contributor.authorCairns, Karen
dc.contributor.authorO'Neill, Vikki
dc.contributor.authorLamrock, Felicity
dc.contributor.authorJørgensen, Torben
dc.contributor.authorBrenner, Hermann
dc.contributor.authorSchöttker, Ben
dc.contributor.authorWilsgaard, Tom
dc.contributor.authorSiganos, Galatios
dc.contributor.authorKuulasmaa, Kari
dc.contributor.authorBoffetta, Paolo
dc.contributor.authorTrichopoulou, Antonia
dc.contributor.authorKee, Frank
dc.date.accessioned2017-03-11T09:15:09Z
dc.date.available2017-03-11T09:15:09Z
dc.date.issued2016-01-18
dc.description.abstractSeldom have studies taken account of changes in lifestyle habits in the elderly, or investigated their impact on disease-free life expectancy (LE) and LE with cardiovascular disease (CVD). Using data on subjects aged 50+ years from three European cohorts (RCPH, ESTHER and Tromsø), we used multi-state Markov models to calculate the independent and joint effects of smoking, physical activity, obesity and alcohol consumption on LE with and without CVD. Men and women aged 50 years who have a favourable lifestyle (overweight but not obese, light/moderate drinker, non-smoker and participates in vigorous physical activity) lived between 7.4 (in Tromsø men) and 15.7 (in ESTHER women) years longer than those with an unfavourable lifestyle (overweight but not obese, light/moderate drinker, smoker and does not participate in physical activity). The greater part of the extra life years was in terms of “disease-free” years, though a healthy lifestyle was also associated with extra years lived after a CVD event. There are sizeable benefits to LE without CVD and also for survival after CVD onset when people favour a lifestyle characterized by salutary behaviours. Remaining a non-smoker yielded the greatest extra years in overall LE, when compared to the effects of routinely taking physical activity, being overweight but not obese, and drinking in moderation. The majority of the overall LE benefit is in disease free years. Therefore, it is important for policy makers and the public to know that prevention through maintaining a favourable lifestyle is “never too late”.en_US
dc.description.sponsorshipData used throughout the present study are derived from the CHANCES project. This work was supported by funding from the European Community’s Seventh Framework Programme (FP7/2007–2013) (Grant Number HEALTH-F3-2010-242244). The ESTHER study was funded by the Baden-Württemberg state Ministry of Science, Research and Arts (Stuttgart, Germany), the Federal Ministry of Education and Research (Berlin, Germany) and the Federal Ministry of Family Affairs, Senior Citizens, Women and Youth (Berlin, Germany).en_US
dc.descriptionSource: <a href=http://dx.doi.org/10.1007/s10654-015-0112-8>doi: 10.1007/s10654-015-0112-8</a>en_US
dc.identifier.citationO’Doherty, M.G., Cairns, K., O’Neill, V. et al. Eur J Epidemiol (2016) 31: 455. doi:10.1007/s10654-015-0112-8en_US
dc.identifier.cristinIDFRIDAID 1417669
dc.identifier.doi10.1007/s10654-015-0112-8
dc.identifier.issn0393-2990
dc.identifier.issn1573-7284
dc.identifier.urihttps://hdl.handle.net/10037/10570
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.relation.journalEuropean Journal of Epidemiology
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750en_US
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Epidemiologi medisinsk og odontologisk statistikk: 803en_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Epidemiology medical and dental statistics: 803en_US
dc.titleEffect of major lifestyle risk factors, independent and jointly, on life expectancy with and without cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES)en_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


File(s) in this item

Thumbnail

This item appears in the following collection(s)

Show simple item record