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dc.contributor.authorRoswall, Nina
dc.contributor.authorLi, Yingjun
dc.contributor.authorSandin, Sven
dc.contributor.authorStröm, Peter
dc.contributor.authorAdami, Hans Olov
dc.contributor.authorWeiderpass, Elisabete
dc.date.accessioned2018-02-06T10:00:15Z
dc.date.available2018-02-06T10:00:15Z
dc.date.issued2017-01
dc.description.abstractObjective:<br>Most studies on obesity and mortality use a single anthropometric measure. Less is known about the effects of weight change on mortality. This study examined changes in body mass index (DBMI) and waist circumference (DWC) and subsequent all-cause and cause-specific mortal ity.<br>Methods:<br>The study was conducted in the Women’s Lifestyle and Health cohort, using self-reported anthropometric measures from 1991 to 1992 and 2003. Hazard ratios of mortality and 95% confidence intervals were calculated using Cox proportional hazards models. DBMI and DWC were examined in quartiles of absolute and relative change, with the second quartile (moderate gain) as the reference.<br>Results:<br>There was a higher risk of death in the first quartile of relative DBMI: HR 1.28 (1.04–1.56). Absolute DBMI suggested the same pattern, but the result was non significant. DWC was not associated with mortality. In cause-specific analyses, the association remained significant for cancer mortality only. In sensitivity analyses excluding the first 5 years of follow-up, the association was, however, attenuated.<br>Conclusions:<br>This study found a higher risk of death among women in the first quartile of relative DBMI compared with the second. It was driven by cancer mortality but may be ascribed to reverse causality. DWC was not associated with mortality.en_US
dc.descriptionAccepted manuscript version. Published version available in <a href=http:dx.doi.org/10.1002/oby.21675>Obesity. (2017);25(1):215-222</a>en_US
dc.identifier.citationRoswall, N., Li, Y., Sandin, S., Ström, P., Adami, H.O., Weiderpass, E. Changes in body mass index and waist circumference and concurrent mortality among Swedish women. Obesity. 2017;25(1):215-222en_US
dc.identifier.cristinIDFRIDAID 1463189
dc.identifier.doi10.1002/oby.21675
dc.identifier.issn1930-7381
dc.identifier.issn1930-739X
dc.identifier.urihttps://hdl.handle.net/10037/12093
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.journalObesity
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en_US
dc.titleChanges in body mass index and waist circumference and concurrent mortality among Swedish womenen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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