Blar i forfatter Prosjektoppgave forskerlinja i medisin "Selli, Anders Lund"
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Treatment of Cardiovascular Dysfunction With PDE5-Inhibitors – Temperature Dependent Effects on Transport and Metabolism of cAMP and cGMP
Selli, Anders Lund (Master thesis; Mastergradsoppgave, 2023-10-21)Introduction: Cardiovascular dysfunction is a potentially lethal complication of hypothermia. Due to a knowledge gap, pharmacological interventions are not recommended at core temperatures below 30°C. Yet, further cooling is induced in surgical procedures and survival of accidental hypothermia is reported after rewarming from below 15°C, advocating a need for evidence-based treatment guidelines. In ...