Dey, Hymonti; Simonovic, Danijela; Hagen, Ingrid Sofie Norberg-Schulz; Vasskog, Terje; Fredheim, Elizabeth G. Aarag; Blencke, Hans-Matti; Anderssen, Trude; Strøm, Morten B.; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-10)
We have synthesised short analogues of the marine antimicrobial peptide Turgencin A
from the colonial Arctic ascidian Synoicum turgens. In this study, we focused on a central, cationic
12-residue Cys-Cys loop region within the sequence. Modified (tryptophan- and arginine-enriched)
linear peptides were compared with Cys-Cys cyclic derivatives, and both linear and Cys-cyclic
peptides were N-terminally ...