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dc.contributor.authorJohansen, Jeanette Schultz
dc.contributor.authorHavnes, Kjerstin
dc.contributor.authorHalvorsen, Kjell H.
dc.contributor.authorHaustreis, Stine-Mari
dc.contributor.authorSkaue, Lillann Wilsgård
dc.contributor.authorKamycheva, Elena
dc.contributor.authorMathiesen, Liv
dc.contributor.authorViktil, Kirsten Kilvik
dc.contributor.authorGranås, Anne Gerd
dc.contributor.authorGarcia, Beate Hennie
dc.date.accessioned2018-04-23T09:15:44Z
dc.date.available2018-04-23T09:15:44Z
dc.date.issued2018-01-23
dc.description.abstract<p><i>Introduction:</i> Drug-related problems (DRPs) are common in the elderly, leading to suboptimal therapy, hospitalisations and increased mortality. The integrated medicines management (IMM) model is a multifactorial interdisciplinary methodology aiming to optimise individual medication therapy throughout the hospital stay. IMM has been shown to reduce readmissions and drug-related hospital readmissions. Using the IMM model as a template, we have designed an intervention aiming both to improve medication safety in hospitals, and communication across the secondary and primary care interface. This paper presents the study protocol to explore the effects of the intervention with regard to healthcare use, health-related quality of life (HRQoL) and medication appropriateness in elderly patients. <p><i>Methods and analysis:</i> A total of 500 patients aged ≥70 years will be included and randomised to control (standard care) or intervention group (1:1). The intervention comprises five steps mainly performed by pharmacists: (1) medication reconciliation at admission, (2) medication review during hospital stay, (3) patient counselling about the use of medicines, (4) a comprehensible and patientfriendly medication list with explanations in discharge summary and (5) postdischarge phone calls to the primary care level. The primary outcome is the difference between intervention and control patients in the rate of emergency medical visits (acute readmissions and visits to emergency department) 12 months after discharge. Secondary outcomes include length of index hospital stay, time to first readmission, mortality, hip fractures, strokes, medication changes, HRQoL and medication appropriateness. Patient inclusion started in September 2016. <p><i>Ethics and dissemination:</i> The trial was approved by the Norwegian Centre for Research Data and the Norwegian Data Protection Authority. We aim to publish the results in international peer-reviewed open access journals, at national and international conferences, and as part of two PhD theses.en_US
dc.description.sponsorshipThe Northern Norway Regional Health Authority grant number HST1314-16. The publication fund of UiT—The Arctic University of Norway.en_US
dc.identifier.citationJohansen, J. S., Havnes, K., Halvorsen, K. H., Haustreis, S-M., Skaue, L. W., Kamycheva, E., ... Garcia, B. H. (2018). Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial. BMJ Open, 1-7. http://doi.org/10.1136/bmjopen-2017-020106en_US
dc.identifier.cristinIDFRIDAID 1567109
dc.identifier.doi10.1136/bmjopen-2017-020106
dc.identifier.issn2044-6055
dc.identifier.urihttps://hdl.handle.net/10037/12569
dc.language.isoengen_US
dc.publisherBMJ Publishing Groupen_US
dc.relation.ispartofJohansen, J.S. (2022). Optimizing medication therapy in older hospitalized patients. Identifying potentially inappropriate medications and testing an interdisciplinary intervention. (Doctoral thesis). <a href=https://hdl.handle.net/10037/26022>https://hdl.handle.net/10037/26022</a>.
dc.relation.ispartofHavnes, K. (2022). Optimising drug therapy in older patients. Exploring different approaches across the patient pathway. (Doctoral thesis). <a href=https://hdl.handle.net/10037/27431>https://hdl.handle.net/10037/27431</a>
dc.relation.journalBMJ Open
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710::Farmakologi: 728en_US
dc.subjectVDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710::Pharmacology: 728en_US
dc.titleInterdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trialen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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