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dc.contributor.authorSormunen, Jorma
dc.contributor.authorTalibov, Madar
dc.contributor.authorSparén, Pär
dc.contributor.authorMartinsen, Jan Ivar
dc.contributor.authorWeiderpass, Elisabete
dc.contributor.authorPukkala, Eero
dc.date.accessioned2019-03-11T14:02:48Z
dc.date.available2019-03-11T14:02:48Z
dc.date.issued2018-07-23
dc.description.abstractThe evidence that prostate cancer is associated to physical inactivity is inconsistent. We studied the association of perceived physical workload (PPWL) at work and incidence of prostate cancer in a case-control setting. We used data from the Nordic Occupational Cancer study from Finland and Sweden. Five population controls were selected for each prostate cancer patient, matched on age and country. We had 239,835 cases and 1,199,175 controls in our study. For each case and control we estimated cumulative PPWL based on probability, level and duration of PPWL using the NOCCA Job Exposure Matrix. We then stratified individuals as having no exposure (reference category), low physical activity (below 50th percentile of the exposed), moderate exposure (50th-90th percentile) and high exposure (90th percentile and higher). The hazard ratios for prostate cancer from the lowest to highest cumulative PPWL levels were 0.90 (95% confidence interval 0.89-0.91), 0.88 (0.87-0.89) and 0.93 (0.92-0.95). There was no statistically significant dose response effect of PPWL on prostate cancer incidence. Inclusion of socioeconomic status in the model did not substantially change the result. The results were similar before Prostate Specific Antigen (PSA) testing and during the years of PSA testing in these countries. In summary, individuals with physical strain at work had a lower risk of invasive prostate cancer as compared to individuals without physical strain at work.en_US
dc.descriptionSource at <a href=https://doi.org/10.22034/APJCP.2018.19.8.2331>https://doi.org/10.22034/APJCP.2018.19.8.2331. </a>en_US
dc.identifier.citationSormunen, J., Talibov, M., Sparén, P., Martinsen, J.I., Weiderpass, E. & Pukkala, E. (2018). Perceived physical strain at work and incidence of prostate cancer - A case-control study in Sweden and Finland. <i>Asian Pacific Journal of Cancer Prevention, 19</i>(8), 2331-2335. https://doi.org/10.22034/APJCP.2018.19.8.2331en_US
dc.identifier.cristinIDFRIDAID 1607730
dc.identifier.doi10.22034/APJCP.2018.19.8.2331
dc.identifier.issn1513-7368
dc.identifier.urihttps://hdl.handle.net/10037/14938
dc.language.isoengen_US
dc.publisherWest Asia Organization for Cancer Preventionen_US
dc.relation.journalAsian Pacific Journal of Cancer Prevention
dc.rights.accessRightsopenAccessen_US
dc.subjectEpidemiologyen_US
dc.subjectinvasive prostate canceren_US
dc.subjectphysical workloaden_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en_US
dc.titlePerceived physical strain at work and incidence of prostate cancer - A case-control study in Sweden and Finlanden_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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