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dc.contributor.authorHansen, Tonje Elisabeth
dc.contributor.authorEvjenth, Bjørg
dc.contributor.authorHolt, jan
dc.date.accessioned2019-05-24T11:24:03Z
dc.date.available2019-05-24T11:24:03Z
dc.date.issued2018-10-01
dc.description.abstract<p><i>Aim - </i>The aim of this study was to identify possible risk factors for current asthma revealed by two studies in Northern Norway in 1985 and 2008 and to evaluate these factors contributing to the increased prevalence of asthma over these 23 years. <p><i>Methods - </i>As part of the ‘Asthma and allergy study among schoolchildren in Nordland county’ we performed a case–control study (70.0% attendance) comparing 153 children with current asthma (cases) to their non‐asthmatic controls. The results from this 2008 study were compared to a similar case–control study (93.2% attendance) performed in 1985 based on 62 current asthmatics. <p><i>Results - </i>In 1985, the most important risk factors for current asthma were repeated lower respiratory tract infections (LRTIs) with adjusted odds ratio (aOR) 52.11, together with urticaria ever and atopic disease in the family. In 2008, the most important risk factors were food allergy with aOR 7.06, LRTIs during the first three years of life with aOR 5.80 and hospitalisation caused by LRTIs. <p><i>Conclusion - </i>In both studies, LRTI was the most important risk factor for current asthma. Whether or not LRTIs have contributed to the increased asthma prevalence in this population over 23 years remains unresolved.en_US
dc.description.sponsorshipNorthern Norway Regional health Authority (Helse Nord RHF)en_US
dc.descriptionThis is the peer reviewed version of the following article: Hansen, T.E., Evjenth, B. & Holt, J. (2018). Lower respiratory tract infections appear to be the most important risk factor for current asthma in subarctic schoolchildren. <i>Acta Paediatrica, 108</i>(5), 911-919, which has been published in final form at <a href=https://doi.org/10.1111/apa.14603>https://doi.org/10.1111/apa.14603</a>. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.en_US
dc.identifier.citationHansen, T.E., Evjenth, B. & Holt, J. (2018). Lower respiratory tract infections appear to be the most important risk factor for current asthma in subarctic schoolchildren. <i>Acta Paediatrica, 108</i>(5), 911-919. https://doi.org/10.1111/apa.14603en_US
dc.identifier.cristinIDFRIDAID 1674393
dc.identifier.doi10.1111/apa.14603
dc.identifier.issn0803-5253
dc.identifier.issn1651-2227
dc.identifier.urihttps://hdl.handle.net/10037/15379
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.ispartofHansen, T.E. (2019). The prevalence and possible risk factors of asthma in a subarctic child population. A study of asthma and allergy among schoolchildren i Nordland county. (Doctoral thesis). <a href=https://hdl.handle.net/10037/15313>https://hdl.handle.net/10037/15313</a>
dc.relation.journalActa Paediatrica
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Epidemiology medical and dental statistics: 803en_US
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Epidemiologi medisinsk og odontologisk statistikk: 803en_US
dc.subjectAsthmaen_US
dc.subjectCase-controlen_US
dc.subjectRisk factorsen_US
dc.subjectSchoolchildrenen_US
dc.subjectSubarcticen_US
dc.titleLower respiratory tract infections appear to be the most important risk factor for current asthma in subarctic schoolchildren.en_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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