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dc.contributor.authorHikmat, Omar
dc.contributor.authorVederhus, Bente Johanne
dc.contributor.authorBenestad, Merete Roineland
dc.contributor.authorEngeset, Ida Malen E.
dc.contributor.authorKlingenberg, Claus
dc.contributor.authorRasmussen, Magnhild
dc.contributor.authorTallaksen, Chantal
dc.contributor.authorBrodtkorb, Eylert
dc.contributor.authorElgen, Irene Bircow
dc.contributor.authorBindoff, Laurence
dc.date.accessioned2020-10-14T16:20:03Z
dc.date.available2020-10-14T16:20:03Z
dc.date.issued2020-09-23
dc.description.abstractWe aimed to assess the impact of POLG disease on mental health and quality of life in 15 patients using the Symptom Checklist-90-R (SCL-90-R)and Short-Form 36 HealthSurvey (RAND-36). Wefound increased scores in all nine subscales of SCL-90-R, particularly phobic anxiety, depression and somatization. Further, patients reported considerably lower scores in all RAND-36 domains. This study revealed a global decline in mental health and poor quality of life in patients with POLG disease and highlights the need for increased awareness andsystematic assessment in order to improve their quality of life and mental health.en_US
dc.identifier.citationHikmat, Vederhus, Benestad, Engeset, Klingenberg, Rasmussen, Tallaksen, Brodtkorb, Elgen, Bindoff. Mental health and health related quality of life in mitochondrial POLG disease. Mitochondrion (Amsterdam. Print). 2020;55:95-99en_US
dc.identifier.cristinIDFRIDAID 1838583
dc.identifier.doi10.1016/j.mito.2020.09.005
dc.identifier.issn1567-7249
dc.identifier.issn1872-8278
dc.identifier.urihttps://hdl.handle.net/10037/19604
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalMitochondrion (Amsterdam. Print)
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2020 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700en_US
dc.subjectVDP::Medisinske Fag: 700en_US
dc.titleMental health and health related quality of life in mitochondrial POLG diseaseen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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