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dc.contributor.authorBystad, Martin
dc.contributor.authorStorø, Benedicte Haug
dc.contributor.authorGundersen, Nina
dc.contributor.authorLarsen Wiik, Ida Karine
dc.contributor.authorNordvang, Lene
dc.contributor.authorGrønli, Ole
dc.contributor.authorRasmussen, Ingrid Daae
dc.contributor.authorAslaksen, Per M.
dc.date.accessioned2021-01-23T15:19:01Z
dc.date.available2021-01-23T15:19:01Z
dc.date.issued2020-10-01
dc.description.abstractThe aim of this study was to investigate whether transcranial Direct Current Stimulation (tDCS) could improve verbal memory functions in healthy old and younger participants. We hypothesized that active tDCS led to significantly improved memory function, compared to placebo tDCS. Forty healthy participants (20 old and 20 younger participants) were included in the study. We applied a novel stimulation protocol, where six sessions of anodal tDCS were administrated during two consecutive days. Each tDCS session lasted 30 min. The current intensity was 2mA and the stimulation area was the left temporal lobe at T3 in the 10–20 EEG system. Immediate recall, delayed recall and recognition memory were assessed with California Verbal Learning Test II (CVLT-II) and executive functions were assessed with the Trail Making Test (TMT) before the first tDCS session and after the last tDCS session. Half of the participants received placebo tDCS, whereas the other half received active tDCS. We did not reveal any significant differences between active and placebo tDCS in memory functions. However, there was a significant difference between active and placebo tDCS in executive function measured by the Trail Making Test (TMT). This experimental study failed to reveal significant differences between active and placebo accelerated tDCS for verbal memory functions. However, accelerated tDCS was found to be well-tolerated in this study.en_US
dc.identifier.citationBystad, Storø, Gundersen, Larsen Wiik, Nordvang, Grønli, Rasmussen, Aslaksen. Can accelerated transcranial direct current stimulation improve memory functions? An experimental, placebo-controlled study. Heliyon. 2020;6(10)en_US
dc.identifier.cristinIDFRIDAID 1836805
dc.identifier.doi10.1016/j.heliyon.2020.e05132
dc.identifier.issn2405-8440
dc.identifier.urihttps://hdl.handle.net/10037/20436
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalHeliyon
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2020 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Neurology: 752en_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Nevrologi: 752en_US
dc.titleCan accelerated transcranial direct current stimulation improve memory functions? An experimental, placebo-controlled studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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