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dc.contributor.authorNieder, Carsten
dc.contributor.authorKämpe, Thomas A
dc.date.accessioned2021-04-15T13:19:30Z
dc.date.available2021-04-15T13:19:30Z
dc.date.issued2020-03-04
dc.description.abstractBackground/Aim: Recent studies suggested that patients with oligometastases have a better prognosis compared with those who have widespread dissemination. In both groups, radiotherapy is a commonly applied treatment. Patient-reported symptoms might depend on the burden of disease. Possibly, oligometastatic patients report lower scores for symptoms, such as fatigue or reduced appetite, which tend to worsen as the disease progresses to a later stage. Therefore, we analyzed the symptom scores in two groups of patients with or without oligometastatic disease. Patients and Methods: A retrospective study was performed in 83 patients who received palliative, non-ablative radiotherapy for distant metastases. The Edmonton Symptom Assessment Scale (ESAS) was employed to assess the pre-radiotherapy symptoms. Results: The oligometastatic group was smaller than anticipated (n=11). The ESAS score differences were not statistically significant. However, oligometastatic patients reported less fatigue, pain and dry mouth (p<0.2). They also had a better performance status. The median survival of oligometastatic patients was longer (8.1 vs. 5.5 months, p=0.17), in the absence of ablative metastases-directed treatment. Conclusion: The oligometastatic state is not a major contributor to the variable patient-reported symptom scores.en_US
dc.identifier.citationNieder C, Kämpe TA. Symptom burden in patients with oligometastases at the start of palliative radiotherapy. Anticancer Research. 2020;40(3):1551-1554en_US
dc.identifier.cristinIDFRIDAID 1809289
dc.identifier.doi10.21873/anticanres.14101
dc.identifier.issn0250-7005
dc.identifier.issn1791-7530
dc.identifier.urihttps://hdl.handle.net/10037/20894
dc.language.isoengen_US
dc.publisherInternational Institute of Anticancer Researchen_US
dc.relation.journalAnticancer Research
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserveden_US
dc.subjectVDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710en_US
dc.subjectVDP::Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710en_US
dc.titleSymptom burden in patients with oligometastases at the start of palliative radiotherapyen_US
dc.type.versionacceptedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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