English
norskEffects of a parent-administered exercise program in the neonatal intensive care unit: Dose does matter-a randomized controlled trial
Permanent link
https://hdl.handle.net/10037/20909
Date
2020-04-06Type
Journal articleTidsskriftartikkel
Peer reviewed
Abstract
Objective - The objectives of this study were to examine the effectiveness of a parent-administered exercise program in the NICU on motor outcome at 3 months corrected age (CA) and the effect of dosing on motor performance.
Design - This was a randomized clinical trial. Setting The study was conducted at 3 university hospitals in Tromsø, Trondheim, and Oslo, Norway.
Participants - A total of 153 infants with gestational age <32 weeks at birth were randomly assigned to intervention or control groups.
Intervention - A 3-week parent-administered intervention designed to facilitate movements in preterm infants was performed in the NICU. Parents were asked to administer the intervention 10 minutes twice a day.
Measurements - Test of Infant Motor Performance (TIMP) was used to assess short-term outcome at 3 months CA.
Results - No significant difference in the TIMP z-score was found between intervention and control groups at follow-up 3 months CA, but a significant positive relationship was found between total intervention dose and TIMP z-scores. The adjusted odds of having a clinical z-score < 0 at 3 months CA was about 6 times higher for infants with less than median intervention time than for infants with a longer intervention time.
Limitations - The number of infants born before 28 weeks was small. A spillover effect in favor of the control group was possible. We do not know if the infants received physical therapy after discharge from the hospital.
Conclusions - There was no difference in motor performance between the intervention group and the control group at 3 months CA. However, an increased intervention dose was positively associated with improved motor outcome.